Gene Information

Name : DICTH_1370 (DICTH_1370)
Accession : YP_002251189.1
Strain : Dictyoglomus thermophilum H-6-12
Genome accession: NC_011297
Putative virulence/resistance : Virulence
Product : negative regulator of genetic competence ClpC/mecB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1305503 - 1307974 bp
Length : 2472 bp
Strand : -
Note : identified by match to protein family HMM PF00004; match to protein family HMM PF02151; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728

DNA sequence :
ATGATGGATAAACTAACACAAAGAGCATACAGAGTACTACTCTTAGCACAGGAGGAGGCACGTAGACTTAACTATTCTAC
AGTAGGAACAGAGCATATTCTCTTAGGGTTGATTCGTGAGGAAGGAGGTATAGCTGCTCAAGTTCTTATAAATCTAGGTC
TTGATCTAAATCATCTTAGGAATGAGATAGAAAGATTAATAGGACGTGGAGATGGTACCTCCTATGGAGCACTTCCCTTC
ACTTCGAGAGCAAAGAAGGTATTGGAATATGCTTCCGAATCTGCCCAAGAACTTAATCATAACTATATTGGAACTGAGCA
TTTGCTTCTTGGTTTATTAAAAGAAGGTGAAGGTGTAGCAGCTCATGTTTTGGAGGGAATGGGAGTAAGGTTGGAGGATG
TTACTATAGAGATATTGAAACTTCTTGGCGAACCTATAGATCCGACTAAGATAAGAGGTAGACAACAAATGAATACTTCT
ACCAATAATTCTTTAAAGAAGAAGCGCACAGTTACAGCAACCTTAGACGAGTTTGGTAGAGATCTAACTCAACTTGCAAG
ACAAGGGAAATTAGATCCTATTATTGGGAGAGAGAAAGAATTAGAAAGAATAATTCAAATTCTTAGTAGAAGAACTAAAA
ATAATCCTGTTCTAGTGGGCGAACCTGGAGTTGGTAAGACAGCTATAGTAGAAGGGCTTGCCCAAAAGATAGTGGAAGGG
GATGTCCCTGATACCTTGTTAAACAAGAGGATAGTTGCTATTGATATGGGAAGCATTGTGGCTGGTACGAAGTATAGAGG
TGAGTTTGAAGAAAGAATGCAGAGAATTATCGAAGAAGTTAAAATGGCAAAGGATGTCATTCTATTTATAGATGAGATTC
ATACTCTGGTAGGAGCAGGAGCAGCAGAAGGAGCGGTTGATGCAGCAAATATTTTGAAGCCCTCCTTAGCAAAGGGGGAG
ATACAGCTAATAGGTGCTACTACTCCTTCTGAATATAGAAAGTATATTGAAAAAGATGGTGCTTTAGAGAGAAGATTCCA
GCCTATAATGGTTGATGAGCCAACTCCCGAAGAAACTATTCAGATATTAAAAGGGTTGAAAGAGAGATATGAAAATTATC
ATAGGGTAAAAATTACCGATGAGGCTATAGAAGAAGCGGTCAAATTATCAGTGAGATATATAACTGATAGATTCTTGCCT
GATAAGGCAATAGATGTGATAGATGAAGCTTCTGCAAGGGTAAGATTAAGAAAGCAAAAGAATACAGCTCAGAGTAATTT
AGAACTTGAATTGGCGAGAATAAGAGAGCAAAAAGAAATTGCTATAAGAAATCAGGCCTTTGAAAGAGCAGCTCAATTGA
GAGATGAAGAAAGAAAGATTGAAGAATATCTTAGAAATTTCATAGATACAACTGCTCCTTCTAACTTTGGAGTGGTAACT
CCAGAGGATGTGGCTCAGGTTGTAGCGACTTGGACTGGAATACCTGTAGCTCAGCTTCTCATTGAAGAAAGAGAAAGATT
GTTAAGAATGGAAGAAGAGCTTCATAAAAGGATTATTTCTCAAGATGAGGCTGTAAGAGTAGTATCTAGAGCTATAAGAA
GATCAAGATCTGGATTAAAAGATCCTAGAAGACCTATAGGGGTATTCATGTTTTTAGGCCCAACGGGTGTTGGTAAGACC
GAGCTTGCAAGAGCTCTTGCAGAGTATCTCTTTGGGAATGAAAATGCTCTGATTAGATTCGATATGTCAGAATTTATGGA
GAAACATACAGTCTCAAGATTAATTGGTGCTCCTCCAGGATATGTAGGATATGAGGAGGGTGGTCAACTTACTGAAAAGG
TTCATAGAAGACCTTATTCGGTTATTCTCTTAGATGAGATAGAAAAAGCTCATAGTGATGTTTTCAATATTCTTTTGCAA
ATAATGGATGAAGGTCAACTTACAGATGGTCATGGTAGAAGGGTAAGCTTCAAAAATACCATACTAATAATGACTTCTAA
TTTTGGTGCAGAATACTTTAAGCAAGAGGCAAGTATAGGTTTTGCTTCCAAAGAAGACAGGGAGAAGTCTTTTGATAAGA
TAAAAGAATTGATTTTGAGTGAGATGAAGAAATACTTCAGGCCAGAATTTCTGAATAGGCTTGATGAGATCGTGTTCTTC
AGGCCACTTACTAAAGATGATCTAAAGCAGATTTTAGAGCTACTGTTAAAACCAGTTAGAGAGAGATTGAGAGAGAAGAG
ATTAGATTTAGAAATAAGTGACGAGGTCAAAGAGTTCTTGCTTGAGAAGGGTTATGATCCTCAATATGGTGCAAGACCTC
TAAAGAGGACAATTCAATACTATATGGAAGATCCTTTGGCAGAATTTATACTTCAAGGAGAGTTCAAAGAAGGAGATGTT
ATAAAAGCAGAACTTGATAAGAAAGGAAATATAGTTTTTAGAAAGTTGGCTTTTGCAAAAGAGCCTTCATAG

Protein sequence :
MMDKLTQRAYRVLLLAQEEARRLNYSTVGTEHILLGLIREEGGIAAQVLINLGLDLNHLRNEIERLIGRGDGTSYGALPF
TSRAKKVLEYASESAQELNHNYIGTEHLLLGLLKEGEGVAAHVLEGMGVRLEDVTIEILKLLGEPIDPTKIRGRQQMNTS
TNNSLKKKRTVTATLDEFGRDLTQLARQGKLDPIIGREKELERIIQILSRRTKNNPVLVGEPGVGKTAIVEGLAQKIVEG
DVPDTLLNKRIVAIDMGSIVAGTKYRGEFEERMQRIIEEVKMAKDVILFIDEIHTLVGAGAAEGAVDAANILKPSLAKGE
IQLIGATTPSEYRKYIEKDGALERRFQPIMVDEPTPEETIQILKGLKERYENYHRVKITDEAIEEAVKLSVRYITDRFLP
DKAIDVIDEASARVRLRKQKNTAQSNLELELARIREQKEIAIRNQAFERAAQLRDEERKIEEYLRNFIDTTAPSNFGVVT
PEDVAQVVATWTGIPVAQLLIEERERLLRMEEELHKRIISQDEAVRVVSRAIRRSRSGLKDPRRPIGVFMFLGPTGVGKT
ELARALAEYLFGNENALIRFDMSEFMEKHTVSRLIGAPPGYVGYEEGGQLTEKVHRRPYSVILLDEIEKAHSDVFNILLQ
IMDEGQLTDGHGRRVSFKNTILIMTSNFGAEYFKQEASIGFASKEDREKSFDKIKELILSEMKKYFRPEFLNRLDEIVFF
RPLTKDDLKQILELLLKPVRERLREKRLDLEISDEVKEFLLEKGYDPQYGARPLKRTIQYYMEDPLAEFILQGEFKEGDV
IKAELDKKGNIVFRKLAFAKEPS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 54

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
DICTH_1370 YP_002251189.1 negative regulator of genetic competence ClpC/mecB VFG0079 Protein 0.0 56
DICTH_1370 YP_002251189.1 negative regulator of genetic competence ClpC/mecB VFG0080 Protein 8e-149 51