Gene Information

Name : pyk (THEYE_A0679)
Accession : YP_002248521.1
Strain : Thermodesulfovibrio yellowstonii DSM 11347
Genome accession: NC_011296
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 674086 - 675504 bp
Length : 1419 bp
Strand : +
Note : identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064

DNA sequence :
ATGAAAAAAGCCAAGATTGTCTGTACAATAGGTCCTTCTTCCGAAAACAGAGAAATAATTCGCAGGATGATAGAAAGCGG
AATGGATGTAGCAAGACTCAATTTTTCACATGGTAATTATGAATGGTTTGAAAATATTATAAAAACAATCCGAGAAGAAG
CAAAAAACATTAAAAAATCAATAGCTATCTTACAAGACCTTCAGGGAGTTAAAATTAGAATAAGTGATGTGGAAAATGAA
GAAATTCACTTAAATGATGGAATGATAGTAGAAATTTATTCTGGTAACGAAGTTTCAAACACAAATAGAATCTTTATTTC
TTATCCATCCCTGATAGAAGATGTAGAGCCTGGAGAAGATATTCTAATAGATGATGGAATTTTGAAAATTAAAGTAATTG
ATAAACTTCAAGATAGATTAATTGGACAAGTCATAGAAGGAGGGATTCTTAAATCCAGAAAAGGTATAAATCTTCCATTT
ACAAGAACTTCTATAAGTTCTTTTACAGAAAAAGATAAATCTGATCTTCTTTTCGGAATTAAAATGGATGTGGACTATGT
TGCTGTATCCTTTGTAAGAAATGCAGATGATATTGAATTAATTAAAGAATGGGCAAATGAAAAAAATATTGTTCTACCTC
CTGTAATTGCTAAGATAGAAAAAAGAGAGGCGCTCAAAAAAATTCATGAAATTCTTGATGTCACTGATGGAATAATGGTA
GCCAGAGGAGATCTTGGCGTTGAACTTCCTGCTGAAGAAGTTCCCTTTTATCAAAAGATGCTTATAGATATTGCAAATCA
AAGGAAAAAGATTGTTATAACAGCAACACAGATGCTTGAATCAATGACAGAACATTCAAGACCAACCAGAGCAGAAGCAA
GTGATGTTGCAAATGCGGTTCTTGACGGAACAGATGCGCTTATGCTTTCTGCAGAGACAGCCAGCGGAAAATATCCTGTT
GAATCAGTTAAAACAATGAGTTCAATTATAAGTTTTACAGAAGAAAGTTTTTCAGATAAAATTGCTACTGCATTTAAAGT
TAGTAAATATTTTCCTGAAGCTATTGCCTCGGGAGCTGTTAGAGTAGCTCAGGATATAGAAGCAAAAGCTATTGTTGTTT
TTACTTACTCAGGATTTTCAGCATTGCTTATTTCTAAACTGAGACCTTTTATGCCTGTAGTAGCATTTACTCCTGATGAA
AAGGTATACAGAAGACTCTCACTTTTATGGGCTGTTATCCCTATGCACATATCTAAAAAAATTGATATGATAGACAATTT
ATTTTTAAAAGAAACTGAAACAGAACTGAAAAAATTAAATCTTGTTAAAGATGGTGATGCAGTTGTATTTGTAGCGAGTT
CGCCTTTTTTAGGAAACAGAAATGTGGTAAGACTTCATAAGGTTGGTGATCCTTTATAA

Protein sequence :
MKKAKIVCTIGPSSENREIIRRMIESGMDVARLNFSHGNYEWFENIIKTIREEAKNIKKSIAILQDLQGVKIRISDVENE
EIHLNDGMIVEIYSGNEVSNTNRIFISYPSLIEDVEPGEDILIDDGILKIKVIDKLQDRLIGQVIEGGILKSRKGINLPF
TRTSISSFTEKDKSDLLFGIKMDVDYVAVSFVRNADDIELIKEWANEKNIVLPPVIAKIEKREALKKIHEILDVTDGIMV
ARGDLGVELPAEEVPFYQKMLIDIANQRKKIVITATQMLESMTEHSRPTRAEASDVANAVLDGTDALMLSAETASGKYPV
ESVKTMSSIISFTEESFSDKIATAFKVSKYFPEAIASGAVRVAQDIEAKAIVVFTYSGFSALLISKLRPFMPVVAFTPDE
KVYRRLSLLWAVIPMHISKKIDMIDNLFLKETETELKKLNLVKDGDAVVFVASSPFLGNRNVVRLHKVGDPL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-67 41
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 8e-68 41
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 8e-68 41
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 3e-67 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_002248521.1 pyruvate kinase VFG0479 Protein 4e-68 41