Gene Information

Name : COPRO5265_0118 (COPRO5265_0118)
Accession : YP_002246488.1
Strain : Coprothermobacter proteolyticus DSM 5265
Genome accession: NC_011295
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 113946 - 115481 bp
Length : 1536 bp
Strand : +
Note : identified by match to protein family HMM PF00117; match to protein family HMM PF00958; match to protein family HMM TIGR00884; match to protein family HMM TIGR00888

DNA sequence :
ATGAAACGAGAAGGAGTAGCTGTTATTGATTTTGGAGGGCAGTATGCGCACCTGATAAGTCGGCGCATCAGGGATTTAGG
TGTTTACGCAGAGATTGTTCCTTATTGGCGGTGGCAGGAAGTACTTGACGACCCCTTGGTGAAAGCCGTTGTGCTTTCTG
GAGGTCCTGCCTCAGTTTATGACGAAAACGCACCTCAGTTGCCAGTTGAGTTTTTCAGCAACGTTACCAAGCCAGTGCTA
GGCATCTGCTACGGTGCCCAGCTCATGGCACATTTGCTCGGTGGCAAGGTAGGCCCTGCCCCTGGTGGTGAATACGGTAG
AACCAAACTTGTTGTAAAAAACTCTGAGCCACTTTTCACTGGCACTCCAACTGCGCAGGATGTGTGGATGAGCCACGGAG
ACCAAGTAGTGGAGCTGCCCAGCGGGTTTGAAGTAAGTGCAAGCACGGAGCATTGCCGTTTAGCAGCATTTCAAAAGGAG
CCTTTGTTTTTTGCTGTGCAGTTTCACCCTGAGGTGGCTCATACGCAGTTTGGGAATGCCCTATTAAAGAACTTTGTCTT
TGGTGTGGCCAAGGCTGAAGTGAACTGGAACATAACAGACTATGTCAGTGAAGCCATAAGGGAGATTAGGGAAACTGTGG
GAGAAAACGGCATGGTACTTGGCGCGCTCAGTGGCGGTGTGGACTCCGCTGTTGCGGCAGTGCTCACCCACAGGGCACTG
GGCTGCGGTAGACTACAGTGCCTCTACATTGATACTGGGCTGCAGCGTGCTGAAGATGAAGCACACGTTAGAAATTTGAG
TAAACACCTGGGCTTAAAGATAAAAGTGGTGGATGCAAAGGAGCGATTCTTAAAAGCCTTAGAAGGCGTTATCGACCCTG
AGCAAAAGAGAAAAATCATAGGAAATCTGTTCATTCAAGTGTTTGAAGAAGAAGCTCGAAACTTGGGGCATTTCGATTTC
CTGCTCCAGGGGACCCTTTATCCCGATGTGATAGAGAGCGGAGAAGGCAGTGCCAGTGTCATAAAATCCCATCATAATGT
TGGCGGTTTGCCCCAGAGTTTGGGACTGAAGCTGCTAGAGCCTTTAAGGTGGCTTTATAAGGATGAGGTTAGGAACATGG
GAAGGTGGCTTGGCATTCCTGAGGACTTTCTGATGCGCCACCCATTTCCTGGTCCAGGGCTGGCTGTACGTACTATAGGC
CCTGTGAAGGAAGAGTACTTAGACATTTTGCGTAGAGCTCACAGCGTTTTAGAGCGTGTGCTTAAAGAGGAAGGCGTCTA
CAATGAACTTTGGCAGGCATTTCCGGTGTTCACGGGTGTGAAAAGTGTGGGTGTAAAAGGTGATGCGCGCCATTACGGAT
GGGTACTTGCTGTTAGAATGGTGCAAAGTGTGGATGCCATGACGGCTGACTGGTACAAAGCTCCACCCGAGCTTTTAGAC
AAGATCGCCAGTTCGCTTATTAGCGAAATTCCAGAGATTTCCAGGGTAGTTTATGACATCACTTCAAAGCCACCTGGAAC
CATTGAATGGGAATAG

Protein sequence :
MKREGVAVIDFGGQYAHLISRRIRDLGVYAEIVPYWRWQEVLDDPLVKAVVLSGGPASVYDENAPQLPVEFFSNVTKPVL
GICYGAQLMAHLLGGKVGPAPGGEYGRTKLVVKNSEPLFTGTPTAQDVWMSHGDQVVELPSGFEVSASTEHCRLAAFQKE
PLFFAVQFHPEVAHTQFGNALLKNFVFGVAKAEVNWNITDYVSEAIREIRETVGENGMVLGALSGGVDSAVAAVLTHRAL
GCGRLQCLYIDTGLQRAEDEAHVRNLSKHLGLKIKVVDAKERFLKALEGVIDPEQKRKIIGNLFIQVFEEEARNLGHFDF
LLQGTLYPDVIESGEGSASVIKSHHNVGGLPQSLGLKLLEPLRWLYKDEVRNMGRWLGIPEDFLMRHPFPGPGLAVRTIG
PVKEEYLDILRRAHSVLERVLKEEGVYNELWQAFPVFTGVKSVGVKGDARHYGWVLAVRMVQSVDAMTADWYKAPPELLD
KIASSLISEIPEISRVVYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-116 49
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-116 49
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-116 49
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-109 47