Gene Information

Name : arcC (COPRO5265_1087)
Accession : YP_002247398.1
Strain : Coprothermobacter proteolyticus DSM 5265
Genome accession: NC_011295
Putative virulence/resistance : Unknown
Product : carbamate kinase-like carbamoyl phosphate synthetase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0549
EC number : 2.7.2.2
Position : 965245 - 966180 bp
Length : 936 bp
Strand : -
Note : this enzyme from Pyrococcus has carbamoyl phosphate synthetase activity even though the enzyme shows sequence and structural similarity to carbamate kinase; this enzyme using carbate and ATP to synthesize carbamoyl phosphate which may be a favorable react

DNA sequence :
ATGAAAGTAGTTCTTGCCTTGGGCGGAAACGCTCTCCAGCTTCCAGACGGGCCCGATGGCATAGAGGGGCAGCAGTATGC
CGCTGAGCGTACTGCTGCTCAGCTTTTGCGACTAGTCACTGATAAGAGTATCAGTTTAGCCATAACCCATGGTAACGGGC
CACAAGTGGGTACAGAACTTCTGCGCCATGACAGGGCAAAGGACGTGGTCACTCCTTTCCCCTTAGATGTGTTGGATGCA
ACTACAGAGGGTTATATTGGGTACGTGCTTCAAAATGCTTTTCATAACGTCGTAGCGCTGGCAAAAGAAAAACGAAGCTT
TGTTTCTTTGGTAACGCAAGTAGTAGTGGATGAGGATGATCCAGCCTTCAATAACCCAAGCAAGTTTGTAGGGCCCACAT
ACGACTACGAGACTGCGATGCAAATTCAAGCTGAAAAAGGCTGGGTTTTCAAAGAGGACAAAGGCAGAGGGTACAGGCGT
GTCGTGCCATCTCCCATGCCGCGTAGAATTGTTGAGCTTTCCTCCATTAGGGCATTAATGGAGGAAAGCATTGTGCCTAT
CACCGTGGGTGGCGGTGGTATTCCTGTTGTGGAGCATGACGGAGCTTTGCGCGGAGTGGAAGCTGTCATTGATAAGGATT
TAGCGTCTTCCTTATTGGCAGTAGAGCTAAAAGCAGAGCTTTTTGTCATATTGACTCAGGTAGACAAGGTCTACATCAAC
TACAAAAGTGATCACCAGCAGCCTTTAGAAAGGGCGAAGCTGGATTACTTAAAAGAGCTCTATGACCAGGGGCACTTCCC
TGCTGGGTCTATGGGTCCCAAGATTTTGGCTGCCATCAAGTACTTGGAAAACGTTGATGGCCAGGTTGCAATTGGGTCTT
TGGAAGAAGCGGAGGCAGTAGTAAGGGGTGTAGCTGGTACAATAGTTTATCGATGA

Protein sequence :
MKVVLALGGNALQLPDGPDGIEGQQYAAERTAAQLLRLVTDKSISLAITHGNGPQVGTELLRHDRAKDVVTPFPLDVLDA
TTEGYIGYVLQNAFHNVVALAKEKRSFVSLVTQVVVDEDDPAFNNPSKFVGPTYDYETAMQIQAEKGWVFKEDKGRGYRR
VVPSPMPRRIVELSSIRALMEESIVPITVGGGGIPVVEHDGALRGVEAVIDKDLASSLLAVELKAELFVILTQVDKVYIN
YKSDHQQPLERAKLDYLKELYDQGHFPAGSMGPKILAAIKYLENVDGQVAIGSLEEAEAVVRGVAGTIVYR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
MW1051 NP_645868.1 carbamate kinase Not tested vSa¥ã Protein 1e-48 45
SAV1170 NP_371694.1 carbamate kinase Not tested vSa¥ã Protein 1e-48 45
SA1013 NP_374286.1 carbamate kinase Not tested vSa¥ã Protein 1e-48 45
arcC YP_493761.1 carbamate kinase Not tested vSa¥ã Protein 1e-48 45
arcC1 YP_186045.1 carbamate kinase Not tested vSa¥ã Protein 1e-48 45
SAKOR_01091 YP_008491279.1 Carbamate kinase Not tested vSa¥ã Protein 1e-48 45
SE0102 NP_763657.1 carbamate kinase Not tested SCCpbp4 Protein 1e-38 44
APECO1_2636 YP_859422.2 carbamate kinase Not tested Not named Protein 3e-38 44