Gene Information

Name : safC (SEN0283)
Accession : YP_002242437.1
Strain : Salmonella enterica P125109
Genome accession: NC_011294
Putative virulence/resistance : Virulence
Product : atypical fimbria outer membrane usher
Function : -
COG functional category : N : Cell motility
COG ID : COG3188
EC number : -
Position : 323101 - 325611 bp
Length : 2511 bp
Strand : +
Note : -

DNA sequence :
ATGAAGTTCAAACAACCTGCCTTGCTACTGTTCATCGCGGGAGTGGTTCATTGCGCAAATGCGCACGCTTACACATTCGA
TGCATCAATGTTGGGCGATGCAGCGAAAGGGGTTGATATGTCGCTCTTTAACCTGGGGGTACAACAGCCAGGGACTTATC
GAGTGGACGTGATGGTGAATGGTAAACGTGTCGACACCCGTGATGTGGTGTTCAAATTGGAAAAGGATGGGCAAGGAACG
CCTTTTCTGGCTCCTTGTTTGACGGTCAGTCAGCTTTCACGCTACGGCGTAAAAACGGAAGATTACCCTCAGTTGTGGAA
AGCAGCAAAGACCCCAGATGAGTGTGCGGATCTGACCGCCATTCCACAGGCTCAAGCGGTACTGGATATCAATAATCAGC
AACTGCAACTGAGTATTTCGCAGTTGGCGTTGCGTCCGGAATTTAAGGGGATCGCTCCTGAAGATCTCTGGGATGATGGT
ATTCCGGCGTTTCTGATGAACTACAGTGCGAGGACAACGCAGACGGATTACAAAATGGATATGGAGAGGCGTGACAACTC
TTCCTGGGTACAACTGCAACCGGGAATCAATATAGGTGCGTGGCGTGTCCGCAATGCGACCAGCTGGCAGCGGAGTAGTC
AACTGTCGGGGAAGTGGCAGGCAGCATATACCTATGCTGAGCGTGGACTGTACTCACTAAAAAGTCGTCTGACTCTGGGG
CAAAAGACTTCGCAGGGGGAGATATTTGATAGTGTGCCATTTACCGGTGTGATGTTGGCATCGGATGACAACATGGTGCC
CTACAGTGAGCGGCAGTTTGCTCCGGTAGTGCGTGGAATTGCCCGCACGCAGGCTCGGGTGGAGGTCAAACAGAATGGTT
ACACCATTTACAACACCACCGTGGCGCCCGGACCGTTTGCACTGCGGGATCTGTCGGTAGCAGACAGTAGTGGTGATCTG
CATGTCACCGTGTGGGAGGCCGATGGCAGTACACAAATGTTTGTGGTGCCGTATCAGACCCCGGCGATAGCACTGCACCA
GGGATATTTGAAGTACAGCCTGTTGGCGGGCCGATACCGATCGTCAGACTCTGCAACAGATAAGGCGCAGATCGCGCAGG
CTACGTTGATGTATGGTCTGCCGTGGAATCTCACTGCATACGGCGGTATACAGAGTGCAACGCACTATCAAGCTGCATCG
CTTGGTTTGGGGGGATCTCTCGGGCGGTGGGGGAGTTTATCTGTCGATGGAAGCGACACACACAGTCAGCGTCAGGGGGA
GGCGGTACAGCAAGGAGCCTCCTGGCGACTGCGTTACAGCAACCAGCTGACTGCGACGGGGACAAATTTTTTTCTGACGA
GATGGCAGTATGCCTCGCAGGGCTATAACACCTTATCCGATGTGCTCGACAGTTATCGACATGATGGCAACCGTCTATGG
TCGTGGCGAGATAATTTGCAGCCGAGCTCGCGTACCACCCTGATGTTGAGTCAGTCATGGGGGAGGCATTTGGGCAATCT
GAGTTTAACCGGTTCCCGTACCGACTGGCGTAATCGCCCCGGTCATGATGACAGCTACGGACTGAGTTGGGGAACCTCTA
TCGGAGGGGGCTCGCTGTCATTGAACTGGAATCAAAACAGAACGCTGTGGCGCAATGGCGCGCACCGTAAAGAGAACATA
ACCAGCCTGTGGTTCAGTATGCCATTAAGCCGCTGGACGGGGAATAATGTAAGTGCTAGTTGGCAGATGACTTCACCATC
ACACGGTGGTCAGACGCAACAAGTGGGGGTCAACGGAGAGGCATTCAGTCAGCAACTGGATTGGGAGGTGCGTCAGAGTT
ACCGTGCCGATGCCCCGCCAGGTGGTGGTAATAACAGCGCATTGCACTTGGCATGGAATGGGGATTACGGCCTGTTAGGT
GGTGACTATAGCTACAGCCGGGCGATGCGCCAGATGGGAGCCAATATCGCGGGAGGTATAGTTATCCACCATCATGGTGT
GACGCTGGGGCAACCTTTGCAAGGCTCAGTGGCGCTGGTTGAAGCGCCAGGGGCCTCGGGGGTGCCAGTTGGCGGCTGGC
CTGGCGTTAAGACGGATTTTCGTGGCGACACCACAGTGGGCAACCTGAGCGTCTATCAGGAGAATACAGTCAGCCTCGAT
CCGTCGCGACTACCGGATGACGCAGAGGTCACACAAACCGATGTGCGCGTGGTGCCAACCGAAGGGGCGGTGGTGGAAGC
GAAGTTTCACACTCGCATCGGGGCCAGGGCACTGATGACGCTGAAACGGGAAGATGGGAGCGCCATTCCTTTCGGGGCGC
AGGTTACAGTCAATGGGCAGGATGGCAGTGCTGCTCTGGTGGATACTGATAGCCAGGTTTATCTCACTGGTCTGGCGGAT
AAGGGCGAACTGACGGTGAAATGGGGAGCACAGCAATGTCGGGTTAACTACCAGCTACCTGCCCACAAGGGAATCGCGGG
CTTGTATCAAATGAGCGGTCTCTGCAGATAG

Protein sequence :
MKFKQPALLLFIAGVVHCANAHAYTFDASMLGDAAKGVDMSLFNLGVQQPGTYRVDVMVNGKRVDTRDVVFKLEKDGQGT
PFLAPCLTVSQLSRYGVKTEDYPQLWKAAKTPDECADLTAIPQAQAVLDINNQQLQLSISQLALRPEFKGIAPEDLWDDG
IPAFLMNYSARTTQTDYKMDMERRDNSSWVQLQPGINIGAWRVRNATSWQRSSQLSGKWQAAYTYAERGLYSLKSRLTLG
QKTSQGEIFDSVPFTGVMLASDDNMVPYSERQFAPVVRGIARTQARVEVKQNGYTIYNTTVAPGPFALRDLSVADSSGDL
HVTVWEADGSTQMFVVPYQTPAIALHQGYLKYSLLAGRYRSSDSATDKAQIAQATLMYGLPWNLTAYGGIQSATHYQAAS
LGLGGSLGRWGSLSVDGSDTHSQRQGEAVQQGASWRLRYSNQLTATGTNFFLTRWQYASQGYNTLSDVLDSYRHDGNRLW
SWRDNLQPSSRTTLMLSQSWGRHLGNLSLTGSRTDWRNRPGHDDSYGLSWGTSIGGGSLSLNWNQNRTLWRNGAHRKENI
TSLWFSMPLSRWTGNNVSASWQMTSPSHGGQTQQVGVNGEAFSQQLDWEVRQSYRADAPPGGGNNSALHLAWNGDYGLLG
GDYSYSRAMRQMGANIAGGIVIHHHGVTLGQPLQGSVALVEAPGASGVPVGGWPGVKTDFRGDTTVGNLSVYQENTVSLD
PSRLPDDAEVTQTDVRVVPTEGAVVEAKFHTRIGARALMTLKREDGSAIPFGAQVTVNGQDGSAALVDTDSQVYLTGLAD
KGELTVKWGAQQCRVNYQLPAHKGIAGLYQMSGLCR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
safC NP_454907.1 outer-membrane fimbrial usher protein Not tested SPI-6 Protein 0.0 98
afaC AAD44022.2 AfaC Virulence PAI-I AL862 Protein 5e-177 50
afaC ADD91743.1 putative AfaC-VIII usher protein Not tested PAI-I AL862 Protein 2e-179 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
safC YP_002242437.1 atypical fimbria outer membrane usher VFG0853 Protein 0.0 50
safC YP_002242437.1 atypical fimbria outer membrane usher VFG0944 Protein 5e-177 50
safC YP_002242437.1 atypical fimbria outer membrane usher VFG0849 Protein 6e-167 46
safC YP_002242437.1 atypical fimbria outer membrane usher VFG0857 Protein 2e-163 45
safC YP_002242437.1 atypical fimbria outer membrane usher VFG0419 Protein 2e-158 44