Gene Information

Name : tktB (SEN2453)
Accession : YP_002244536.1
Strain : Salmonella enterica P125109
Genome accession: NC_011294
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 2580980 - 2582980 bp
Length : 2001 bp
Strand : +
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGTCCCGTAAAGACCTTGCCAATGCGATTCGTGCGCTGAGCATGGATGCCGTTCAAAAAGCCAATTCCGGGCACCCCGG
CGCGCCGATGGGGATGGCGGATATCGCTGAAGTGCTATGGAACGATTTTCTTAAACATAACCCCACCGATCCAACCTGGT
ATGACCGTGACCGTTTTATCCTTTCCAACGGTCACGCCTCCATGCTGCTCTATAGTCTGCTGCATTTAACCGGTTATGAC
CTGCCGCTGGAGGAGTTAAAAAACTTCCGTCAACTGCACTCTAAAACGCCAGGTCACCCGGAGATTGGCTATACGCCCGG
CGTTGAAACCACCACCGGACCGCTGGGCCAGGGGCTGGCGAATGCCGTCGGGCTGGCGATTGCCGAGCGTACGTTAGGCG
CACAGTTCAACCGGCCGGACCATGAGATTGTCGACCACTACACCTATGTCTTTATGGGCGACGGCTGTCTGATGGAGGGG
ATCTCGCATGAGGTGTGTTCGCTGGCTGGTACGCTGGGACTGGGCAAACTGATCGGCTTTTACGATCACAACGGCATCTC
CATTGATGGCGAAACCGAAGGCTGGTTTACCGACGATACCGCCAAACGTTTTGAAGCCTACCACTGGCATGTCGTATATG
ACATTGACGGGCACGATCCGGAGGCGGTGAAAAAAGCCATTCTCGAAGCCCAGAGCGTAAAAGATAAACCTTCGCTAATT
ATCTGTCGGACGGTGATAGGTTTTGGCTCGCCGAATAAAGCCGGGAAGGAGGAGTCGCACGGCGCGGCGCTGGGCGAAGA
AGAGGTGGCGCTGACTCGCCAGAAGCTGGGATGGCATCATCCGGCGTTTGAGATCCCAAAAGAAATTTACCGCGCGTGGG
ATGGCCGTGAAAAAGGCGAGAAAGCGCAGCAGCAGTGGCAGGAAAAGTTTGCTGCTTATGAGAAGGCTTATCCTGAGCTG
GCCGCGGAGTTTACCCGCCGGATGAGCGGCGGACTGCCGGAGGCATGGGAATCCGCCACGCAAAAATTTATTAACGACTT
GCAGGCTAATCCGGCCAAAATCGCCACCCGTAAAGCATCGCAAAATACGCTCAATGCCTACGGTCCCCTGTTGCCGGAAC
TGTTGGGCGGATCGGCGGATCTGGCGCCGAGCAACCTGACTATCTGGAAAGGTTCGACCTCGTTGAAAGAGGATCCGGCA
GGTAATTATATTCACTATGGCGTGCGCGAATTCGGCATGACCGCCATTGCCAACGGCATCGCCCATCACGGCGGCTTTGT
ACCGTATACCGCCACGTTTCTGATGTTTGTCGAATATGCGCGTAACGCGGCGCGTATGGCGGCCTTAATGAAAGCCCGGC
AGATTATGGTCTATACCCACGACTCCATCGGTTTAGGCGAAGATGGCCCGACGCACCAGGCCGTGGAACAACTGGCGAGC
CTGCGCTTAACGCCAAACTTCAGCACCTGGCGTCCCTGCGATCAGGTTGAGGCGGCGGTCGGCTGGAAGCTGGCCATTGA
ACGTCAGCACGGGCCGACGGCGTTGATTCTCTCGCGGCAAAATCTGGCGCAGGTGGAACGCACGCCGGAACAGGTGAAAG
CGATTGCCCGCGGCGGTTATATTCTGAAAGATAGCGGCGGCAAGCCGGATATCATTCTGATCGCTACCGGATCGGAAATG
GAAATTACCCTCCAGGCGGCGGAAAAATTGACTGGCGAGGGGCATAACGTTCGCGTGGTGTCGTTGCCTTCAACGGATAT
TTTCGATGCGCAGGACGAGGCATATCGCGAATCTGTGCTACCGGCGCACGTGACCGCCCGCGTCGCGGTGGAAGCCGGTA
TAGCCGACTACTGGTATAAATATGTTGGCCTAAAAGGCGCAATTATCGGCATGACGGGATACGGTGAATCCGCCCCGGCT
GACAAACTGTTCCCGTATTTTGGCTTTACCGTGGAAAATATTGTAGAAAAAGCCCGCCGGGTGCTGAACATCAAAGGCTA
A

Protein sequence :
MSRKDLANAIRALSMDAVQKANSGHPGAPMGMADIAEVLWNDFLKHNPTDPTWYDRDRFILSNGHASMLLYSLLHLTGYD
LPLEELKNFRQLHSKTPGHPEIGYTPGVETTTGPLGQGLANAVGLAIAERTLGAQFNRPDHEIVDHYTYVFMGDGCLMEG
ISHEVCSLAGTLGLGKLIGFYDHNGISIDGETEGWFTDDTAKRFEAYHWHVVYDIDGHDPEAVKKAILEAQSVKDKPSLI
ICRTVIGFGSPNKAGKEESHGAALGEEEVALTRQKLGWHHPAFEIPKEIYRAWDGREKGEKAQQQWQEKFAAYEKAYPEL
AAEFTRRMSGGLPEAWESATQKFINDLQANPAKIATRKASQNTLNAYGPLLPELLGGSADLAPSNLTIWKGSTSLKEDPA
GNYIHYGVREFGMTAIANGIAHHGGFVPYTATFLMFVEYARNAARMAALMKARQIMVYTHDSIGLGEDGPTHQAVEQLAS
LRLTPNFSTWRPCDQVEAAVGWKLAIERQHGPTALILSRQNLAQVERTPEQVKAIARGGYILKDSGGKPDIILIATGSEM
EITLQAAEKLTGEGHNVRVVSLPSTDIFDAQDEAYRESVLPAHVTARVAVEAGIADYWYKYVGLKGAIIGMTGYGESAPA
DKLFPYFGFTVENIVEKARRVLNIKG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 0.0 75
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 0.0 66