Gene Information

Name : wzc (SEN2112)
Accession : YP_002244203.1
Strain : Salmonella enterica P125109
Genome accession: NC_011294
Putative virulence/resistance : Unknown
Product : tyrosine kinase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG3206
EC number : 2.7.10.1
Position : 2203506 - 2205665 bp
Length : 2160 bp
Strand : -
Note : Wzc; catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide)

DNA sequence :
ATGACAGAAAAAGTAAAACAATCTGCGGCGGTTACGGGTAGCGATGAAATCGATATCGGGCGCCTGGTCGGAACGGTGAT
TGAAGCGCGTTGGTGGGTGTTGGGGACGACGGCCATATTTGCGCTGTGCGCGGTAATTTATACGTTCTTCGCCACGCCCA
TCTATAGCGCCGATGCGCTGGTGCAGATTGAACAAAACGCCGGTAATTCGCTGGTACAGGATATCAACAGTGCATTAGCG
AATAAGCCGCCGGCTTCCGATGCGGAAATTCAGCTCATTCGATCGCGCCTGGTGCTTGGGAAGACCGTTGACGATCTGGA
TCTGGATATTGCCGTCACCAAAAACACCTTTCCGCTGTTCGGCGCCGGGTGGGAACGGCTGATGGGGCGTCACAATGAAA
TGGTGAAAGTCACGACATTCACCCGACCAGAGACGATGAGCGGACAGATCTTCACCCTCAAAGTGCTGGGCGACAAACGT
TATCAGTTGGTTAGCGACGGCGGATTTAGCGCGCAGGGCGTTGTGGGCCAGCCACTCAATAAAGACGGCGTGACGATGCA
GGTAGAGGCGATTGACGCCCGTCCTGATACAGAATTTACGGTGAGTAAATTCTCAACGCTTGGCATGATTAATAACCTGC
AAAATAACCTCACCGTAACGGAAACCGGCAAAGATACCGGCGTTCTGAGCCTGACGTTCACGGGAGAGGATCGCGACCAG
ATCCGCGAAATTCTCAACAGTATTACCCGTAACTATCTGCAACAGGATATTGCGCGGAAATCTGAAGAGGCGGGGAAGAG
CCTGGCGTTTCTGGCAAAACAACTGCCGGAAGTCCGCAGCCGTCTGGATGTGGCGGAAAACAAGCTAAACGCTTTCCGCC
AGGATAAAGACTCGGTGGATTTACCGCTGGAGGCGAAGGCGGTGCTCGATTCGATGGTTAATATCGACGCCCAGTTGAAT
GAGTTGACGTTTAAAGAGGCGGAAATTTCCAAGCTCTTTACCAAAGCGCATCCGGCCTACCGCACCCTGCTGGAAAAACG
TAAAGCGCTGGAAGATGAAAAAGCCAAACTGAACGGGCGGGTGACGGCAATGCCGAAAACCCAGCAGGAGATTGTGCGTT
TGACCCGCGATGTGGAGTCCGGCCAGCAGGTTTATATGCAACTGCTTAATAAACAGCAGGAGCTGAAAATCACCGAAGCC
AGCACCGTTGGCGATGTGCGCATCGTTGACCCGGCGATTACCCAGCCGGGCGTGCTGAAGCCGAAAAAGGCGTTGATTAT
TCTCGGCAGCATTATTCTGGGATTAATGTTATCGATTGTCGGCGTGCTGCTGCGCTCGCTGTTTAATCGCGGTATCGAAA
GCCCGCAGGCGCTGGAGGAGCACGGGATCAGCGTCTATGCCAGTATTCCGCTGTCGGAATGGCAAAAAGCGCGCGATAGC
GTCAAAACCATTAAAGGGATTAAGCGTTACAAGCAGAGCCAACTGCTGGCGGTGGGCAATCCGACCGATCTGGCGATTGA
GGCGATTCGCAGCCTGCGCACCAGCCTCCATTTCGCCATGATGCAGGCGCAAAATAATGTACTCATGCTCACAGGCGTCA
GCCCCTCTATCGGTAAAACCTTTGTTTGCGCCAACCTGGCGGCCGTCATCAGCCAGACGCATAAACGGGTATTACTGATC
GACTGCGATATGCGCAAGGGCTACACCCATGAACTGCTCGGCACCAATAACGTGGACGGCTTATCTGACATTCTGGCGGG
CAAAGGCGAGATAGCCTCCTGCGCGAAACCTACGGCGATCGCTAATTTTGATCTTATTCCGCGCGGTCAGGTGCCGCCTA
ATCCATCGGAACTGCTGATGAGCGAGCGCTTCGGCGAGCTGATCGCCTGGGCAAGCAGCCGCTACGACCTGGTATTAATC
GACACGCCGCCGATTCTGGCCGTGACGGACGCCGCGATTGTGGGTCGCCACGTCGGGACGACGCTGATGGTGGCGCGTTA
TGCCGTCAACACCTTAAAAGAGGTGGAAACCAGTCTGAGCCGTTTTGACCAGAATGGCATTCAGGTCAAAGGCGTCATTC
TCAACTCCATTTTTCGCCGGGCGACGGGCTACCAGGATTATGGTTATTACGAGTATGAATACCAGTCAGATTCCAAATAA

Protein sequence :
MTEKVKQSAAVTGSDEIDIGRLVGTVIEARWWVLGTTAIFALCAVIYTFFATPIYSADALVQIEQNAGNSLVQDINSALA
NKPPASDAEIQLIRSRLVLGKTVDDLDLDIAVTKNTFPLFGAGWERLMGRHNEMVKVTTFTRPETMSGQIFTLKVLGDKR
YQLVSDGGFSAQGVVGQPLNKDGVTMQVEAIDARPDTEFTVSKFSTLGMINNLQNNLTVTETGKDTGVLSLTFTGEDRDQ
IREILNSITRNYLQQDIARKSEEAGKSLAFLAKQLPEVRSRLDVAENKLNAFRQDKDSVDLPLEAKAVLDSMVNIDAQLN
ELTFKEAEISKLFTKAHPAYRTLLEKRKALEDEKAKLNGRVTAMPKTQQEIVRLTRDVESGQQVYMQLLNKQQELKITEA
STVGDVRIVDPAITQPGVLKPKKALIILGSIILGLMLSIVGVLLRSLFNRGIESPQALEEHGISVYASIPLSEWQKARDS
VKTIKGIKRYKQSQLLAVGNPTDLAIEAIRSLRTSLHFAMMQAQNNVLMLTGVSPSIGKTFVCANLAAVISQTHKRVLLI
DCDMRKGYTHELLGTNNVDGLSDILAGKGEIASCAKPTAIANFDLIPRGQVPPNPSELLMSERFGELIAWASSRYDLVLI
DTPPILAVTDAAIVGRHVGTTLMVARYAVNTLKEVETSLSRFDQNGIQVKGVILNSIFRRATGYQDYGYYEYEYQSDSK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
orf41 AAO18066.1 Orf41 Not tested TTSS locus Protein 3e-159 48