Gene Information

Name : topB (SEN1745)
Accession : YP_002243844.1
Strain : Salmonella enterica P125109
Genome accession: NC_011294
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : 5.99.1.2
Position : 1850731 - 1852680 bp
Length : 1950 bp
Strand : -
Note : decatenates replicating daughter chromosomes

DNA sequence :
ATGCGGTTGTTTATTGCCGAAAAACCGAGTCTGGGGCGCGCCATTGCGGATGTGCTGCCAAAACCGCACCGTAAAGGCGA
TGGTTTTATTGAGTGCGGAAACGGGCAGGTCGTCACCTGGTGTATTGGTCATTTGCTGGAACAGGCGCAGCCGGATGCGT
ATGACAGCCGTTATGCGCGCTGGAATCTGGCTGACCTGCCTATCGTGCCGGAAAAATGGCAGCTTCAGCCTCGTCCTTCC
GTCACCAAACAGCTCAATGTGATTAAGCGCTTTTTGCATCAAGCCGGTGAAATTATTCACGCCGGCGACCCGGATCGCGA
AGGACAGCTTCTGGTTGATGAAGTGCTGGATTATCTCCAGCTTCCTGCCGAAAAGCGCCAGCAGGTGCGGCGTTGTCTGA
TAAACGACCTTAACCCGCAGGCGGTCGAGCGTGCTATTGACAGGCTGCGGGCGAACAGCGACTTCGTGCCGCTGTGCGTC
TCCGCTCTGGCGCGAGCGCGAGCGGACTGGCTGTATGGCATTAATATGACCCGTGCTTACACGATCCTGGGCCGTAATGC
CGGCTATCAGGGCGTGTTATCCGTGGGACGCGTGCAGACGCCTGTACTGGGGCTGGTGGTGCGGCGAGACGAAGAGATTG
AGAACTTCGTCGCCAAAGACTTCTTTGAAGTAAAGGCGCACATCGTTACGCCTGCCGACGAGCGTTTTACCGCTATCTGG
CAGCCGAGCGAGGCGTGCGAACCTTATCAGGATGAAGAGGGGCGCTTGCTTCATCGTCCGCTGGCGGAGCATGTAGTGAA
CCGAATCAACGGTCAGCCCGCGCTGGTAACCAGTTATAATGATAAACGGGAATCAGAATCCGCGCCGCTGCCGTTTTCGC
TCTCGACGCTACAGATTGAAGCCGCCAAACGCTTTGGCCTGAGCGCGCAAAACGTGCTTGATATTTGTCAGAAGCTATAT
GAAACCCACAAACTGATTACCTATCCGCGTTCCGACTGCCGTTATCTGCCGGAAGAACACTTTGCCGGACGGCAGGCGGT
CATGAACGCGATTAGCGTCCACGCCCCGGATTTACTGCCGCAGTCTGTGGTTAATCCTGACACGCGCAATCGCTGCTGGG
ATGACAAAAAAGTGGATGCGCACCACGCGATTATCCCGACGGCGCGCAGTTCTTCTGTCCATTTGACGGAAAACGAAGCG
AAAGTGTACACCCTGATTGCGCGTCAGTATCTGATGCAGTTCTGCCCGGACGCGGTGTTTCGTAAATGCGTTATTGAACT
GGAAATCGCCAAAGGAAAATTTGTCGCCAAAGCGCGTTTTCTGGCGGAGGCCGGTTGGCGGACGTTACTGGGCAGTAAAG
AGCGCGACGAGGAAAACGACGGTACGCCGCTGCCGGTTGTCGCCAAAGGTGATGAGTTGCTGTGTGAAAAGGGGGAAGTG
GTCGAGCGCCAAACCCAGCCGCCGCGTCATTTCACCGATGCGACATTGCTTTCCGCGATGACCGGAATTGCCCGCTTCGT
GCAGGATAAAGATCTGAAAAAGATCCTGCGCGCGACCGATGGGCTGGGGACGGAAGCCACGCGCGCCGGGATTATCGAGC
TGCTGTTCAAACGTAGCTTTCTGACCAAAAAAGGGCGCTACATTCATTCTACCGATGCTGGCAAAGCGTTAATACATTCG
CTGCCGGAAATGGCGGCCCGTCCAGATATGACCGCGCACTGGGAATCTGTTTTGACGCAAATCAGCGAAAAGCAGTGCCG
TTACCAGGATTTTATGCAACCGCTGGTCGGCACGTTATATCAGCTGATCGATCAGGCTAAGCGCACGCCGGTGAAGCGTT
TCAGAGGGATAGTCGCGCCAGGCGGTGGAGAAAAGAAAAAGAGCGCGCCGCGTAAGCGAGCGGGCAAAAAAAGCCCGCCT
GCTGAGGAGACAGGCCGTCAGACCGAATAA

Protein sequence :
MRLFIAEKPSLGRAIADVLPKPHRKGDGFIECGNGQVVTWCIGHLLEQAQPDAYDSRYARWNLADLPIVPEKWQLQPRPS
VTKQLNVIKRFLHQAGEIIHAGDPDREGQLLVDEVLDYLQLPAEKRQQVRRCLINDLNPQAVERAIDRLRANSDFVPLCV
SALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHIVTPADERFTAIW
QPSEACEPYQDEEGRLLHRPLAEHVVNRINGQPALVTSYNDKRESESAPLPFSLSTLQIEAAKRFGLSAQNVLDICQKLY
ETHKLITYPRSDCRYLPEEHFAGRQAVMNAISVHAPDLLPQSVVNPDTRNRCWDDKKVDAHHAIIPTARSSSVHLTENEA
KVYTLIARQYLMQFCPDAVFRKCVIELEIAKGKFVAKARFLAEAGWRTLLGSKERDEENDGTPLPVVAKGDELLCEKGEV
VERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATRAGIIELLFKRSFLTKKGRYIHSTDAGKALIHS
LPEMAARPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLYQLIDQAKRTPVKRFRGIVAPGGGEKKKSAPRKRAGKKSPP
AEETGRQTE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 4e-103 41
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 3e-110 41