Gene Information

Name : tktA_1 (KPK_0742)
Accession : YP_002236615.1
Strain : Klebsiella pneumoniae 342
Genome accession: NC_011283
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : -
Position : 750867 - 752858 bp
Length : 1992 bp
Strand : +
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGTCCTCACGTAAAGAGCTTGCTAACGCTATTCGTGCGCTGAGCATGGACGCTGTACAGAAAGCCAAATCCGGCCACCC
GGGGGCCCCGATGGGTATGGCTGACATTGCCGAAGTGCTGTGGCGTGATTTCCTGAACCATAACCCGAACAATCCGGCCT
GGGCTGACCGTGACCGTTTTGTGTTGTCAAATGGCCATGGTTCGATGCTGATTTACAGCCTGCTGCACCTCACTGGCTAC
GATCTGCCGATTGAAGAGCTGAAAAACTTCCGCCAGCTGCACTCCAAAACCCCGGGTCACCCGGAAGTCGGCTACACCGC
GGGCGTGGAAACCACCACCGGTCCGCTGGGCCAGGGTATCGCTAACGCGGTCGGGATGGCTATCGCCGAGAAAACTCTGG
CGGCGCAGTTCAACCGTCCGGGCCACGATATCGTCGACCACTACACCTACGCCTTCATGGGCGACGGCTGCATGATGGAA
GGCATTTCTCATGAAGTGTGCTCCCTGGCCGGTACTCTGAAACTGGGCAAACTGGTGGCCTTCTATGATGACAACGGCAT
CTCCATCGACGGCCACGTTGAAGGCTGGTTCACCGACGATACCGCGAAACGCTTTGAAGCCTACGGCTGGCACGTGGTAC
GCGGCGTTGACGGTCACGACGCTGACGCCATCAAACGCGCAGTAGAAGAAGCGCGTGCAGTTACCGACAAACCGTCCCTG
CTGATGTGCAAAACCATCATTGGTTTTGGTTCGCCGAACAAAGCCGGTACCCACGACTCCCACGGCGCACCGCTGGGCGA
CGCAGAAATCGCGCTGACCCGCGAAGCGCTGGGCTGGAAACACGCGCCGTTTGACATCCCGTCTGACATCTATGCGCAGT
GGGATGCCAAAGAAGCCGGCCAGGCGAAAGAAGCGGCGTGGAATGAGAAGTTTGCTGCCTACGCGAAAGCCTTCCCGCAG
GAAGCGGCCGAATTCACCCGTCGTATGAAAGGTGAAATGCCGTCTGACTTCGACGCCAAAGCTAACGAGTTCATCGCGAA
GCTGCAGGCTAACCCGGCGAAAATCGCCAGCCGTAAAGCGTCGCAGAATGCTATCGAAGCCTTCGGCCCGCTGCTGCCGG
AATTCCTCGGCGGCTCCGCTGACCTGGCGCCGTCCAACCTGACCCTGTGGTCTGGTTCTAAGCCGATCAACGAAGACACC
GCGGGTAACTACATTCATTACGGCGTGCGTGAATTCGGTATGACCGCTATCGCCAACGGTATCGCGCTGCACGGCGGTTT
CCTGCCGTACACCTCCACCTTCCTGATGTTCGTGGAATACGCGCGTAATGCGGTACGTATGGCCGCGCTGATGAAACAGC
GTCAGGTGATGGTCTACACCCACGACTCCATCGGTCTGGGTGAAGACGGCCCGACTCACCAGCCGGTAGAGCAGGTGGCT
TCCCTGCGCGTGACGCCGAACATGTCCACCTGGCGTCCGTGTGACCAGGTTGAATCCGCGATTGCGTGGAAATATGGCGT
AGAGCGTCAGGACGGCCCGACCGCGCTGATCCTCTCCCGTCAGAACCTGGCGCAGCAGGAGCGTACCGCAGAGCAGCTGG
CAAACGTCGCTCGCGGCGGTTACGTGCTGAAAGATTGTGCCGGCCAGCCGGAGCTGATCTTCATCGCCACCGGTTCCGAA
GTGGAGCTGGCAGTGGCCGCGTGGGACAAACTGACTGCCGAAGGCGTGAAGGCGCGCGTGGTCTCCATGCCGTCCACCGA
CGCGTTCGACAAGCAGGATGCCGCTTATCGTGAATCCGTACTGCCGAAAGCCGTTTCTGCCCGCGTCGCGGTAGAAGCCG
GTATCGCTGACTACTGGTTCAAATACGTTGGCCTGAACGGCGCTATCGTTGGCATGACCACCTTCGGTGAGTCTGCGCCG
GCTGAGCAGCTGTTCGAAGAGTTCGGCTTCACCGTCGACAACGTGGTCGCTAAAGCGAAAGCGCTGCTGTAA

Protein sequence :
MSSRKELANAIRALSMDAVQKAKSGHPGAPMGMADIAEVLWRDFLNHNPNNPAWADRDRFVLSNGHGSMLIYSLLHLTGY
DLPIEELKNFRQLHSKTPGHPEVGYTAGVETTTGPLGQGIANAVGMAIAEKTLAAQFNRPGHDIVDHYTYAFMGDGCMME
GISHEVCSLAGTLKLGKLVAFYDDNGISIDGHVEGWFTDDTAKRFEAYGWHVVRGVDGHDADAIKRAVEEARAVTDKPSL
LMCKTIIGFGSPNKAGTHDSHGAPLGDAEIALTREALGWKHAPFDIPSDIYAQWDAKEAGQAKEAAWNEKFAAYAKAFPQ
EAAEFTRRMKGEMPSDFDAKANEFIAKLQANPAKIASRKASQNAIEAFGPLLPEFLGGSADLAPSNLTLWSGSKPINEDT
AGNYIHYGVREFGMTAIANGIALHGGFLPYTSTFLMFVEYARNAVRMAALMKQRQVMVYTHDSIGLGEDGPTHQPVEQVA
SLRVTPNMSTWRPCDQVESAIAWKYGVERQDGPTALILSRQNLAQQERTAEQLANVARGGYVLKDCAGQPELIFIATGSE
VELAVAAWDKLTAEGVKARVVSMPSTDAFDKQDAAYRESVLPKAVSARVAVEAGIADYWFKYVGLNGAIVGMTTFGESAP
AEQLFEEFGFTVDNVVAKAKALL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 0.0 83
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 0.0 68