Gene Information

Name : glnA (KPK_5504)
Accession : YP_002241251.1
Strain : Klebsiella pneumoniae 342
Genome accession: NC_011283
Putative virulence/resistance : Virulence
Product : glutamine synthetase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0174
EC number : -
Position : 5570310 - 5571719 bp
Length : 1410 bp
Strand : +
Note : forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltra

DNA sequence :
ATGTCCGCTGAACACGTTTTGACGATGCTGAACGAGCACGAAGTGAAGTTTGTCGATCTGCGCTTCACCGATACCAAAGG
TAAAGAACAGCACGTCACGATTCCGTCTCATCAGGTAAATGCCGAATTCTTCGAAGAAGGCAAAATGTTTGATGGCTCCT
CGATCGGTGGCTGGAAAGGTATCAACGAATCTGACATGGTCCTGATGCCGGACGCTTCCACCGCGGTCATTGACCCGTTC
TACGAAGAACCGACCCTGATCATCCGCTGCGATATCCTCGAGCCAGGCACCCTGCAGGGCTATGACCGTGACCCGCGCTC
CATCGCGAAACGCGCTGAAGAGTACCTGCGCGCCACCGGCATCGCTGACACCGTCCTGTTCGGGCCAGAACCAGAATTCT
TCCTGTTCGACGACATCCGTTTTGGCGCCTCTATCTCCGGCTCCCATGTCGCGATCGATGACATCGAAGGTGCGTGGAAC
TCCTCCACCAAATACGAAGGCGGTAACAAAGGTCACCGTCCGGGCGTGAAAGGGGGTTACTTCCCGGTTCCGCCAGTAGA
CTCTTCTCAGGATATCCGTTCCACCATGTGTATGATCATGGAAGAGATGGGCCTGGTTGTTGAAGCTCACCACCACGAAG
TGGCTACCGCAGGTCAGAACGAAGTGGCAACCCGCTTCAACACCATGACCAAAAAAGCGGACGAAATTCAGATTTACAAA
TACGTTGTTCACAACGTCGCTCACCGCTTCGGTAAAACCGCGACCTTTATGCCGAAACCAATGTTCGGCGATAACGGCTC
CGGCATGCACTGCCATATGTCTCTGGCGAAAAACGGGACTAACCTGTTCTCCGGCGACAAATACGCAGGTCTGTCTGAGC
AGGCGCTGTTCTACATCGGCGGCGTAATCAAACACGCTAAAGCTATCAACGCCCTGGCGAACCCGACCACCAACTCCTAC
AAGCGTCTGGTCCCGGGTTACGAAGCGCCGGTTATGCTGGCTTACTCTGCGCGTAACCGCTCTGCCTCCATCCGTATTCC
GGTGGTGACCTCTCCGAAAGCGCGTCGTATCGAAGTGCGCTTCCCGGACCCGGCTGCCAACCCGTACCTGTGCTTTGCGG
CGCTGCTGATGGCTGGCCTTGATGGTATCAAGAACAAAATCCATCCGGGCGAAGCAATGGACAAAAACCTGTATGACCTG
CCGCCGGAAGAAGCGAAAGAGATCCCGCAGGTTGCTGGTTCTCTGGAAGAAGCCCTGCAGGCCCTGGATGCTGACCGCGA
GTTCCTGACGGCTGGCGGCGTGTTCACCAATGACGCTATCGATGCTTACATCGCCCTGCGTCTGGAAGAGAACGACCGCG
TACGCATGACTCCGCATCCGGTTGAGTTCGAACTGTACTACAGCGTCTAA

Protein sequence :
MSAEHVLTMLNEHEVKFVDLRFTDTKGKEQHVTIPSHQVNAEFFEEGKMFDGSSIGGWKGINESDMVLMPDASTAVIDPF
YEEPTLIIRCDILEPGTLQGYDRDPRSIAKRAEEYLRATGIADTVLFGPEPEFFLFDDIRFGASISGSHVAIDDIEGAWN
SSTKYEGGNKGHRPGVKGGYFPVPPVDSSQDIRSTMCMIMEEMGLVVEAHHHEVATAGQNEVATRFNTMTKKADEIQIYK
YVVHNVAHRFGKTATFMPKPMFGDNGSGMHCHMSLAKNGTNLFSGDKYAGLSEQALFYIGGVIKHAKAINALANPTTNSY
KRLVPGYEAPVMLAYSARNRSASIRIPVVTSPKARRIEVRFPDPAANPYLCFAALLMAGLDGIKNKIHPGEAMDKNLYDL
PPEEAKEIPQVAGSLEEALQALDADREFLTAGGVFTNDAIDAYIALRLEENDRVRMTPHPVEFELYYSV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
glnA YP_003728749.1 glutamine synthetase Not tested cag PAI Protein 1e-102 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
glnA YP_002241251.1 glutamine synthetase VFG1399 Protein 3e-115 51