Gene Information

Name : metB (KPK_5446)
Accession : YP_002241193.1
Strain : Klebsiella pneumoniae 342
Genome accession: NC_011283
Putative virulence/resistance : Unknown
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : -
Position : 5514614 - 5515774 bp
Length : 1161 bp
Strand : -
Note : catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine

DNA sequence :
ATGACGCGTAAACAGGCCACCATCGCAGTGCGTAGCGGTTTAAATGACGACGAGCAGTACGGTTGCGTTGTCCCGCCGAT
CCACCTTTCCAGTACCTATAACTTCACCGGCTTTAATGAACCTCGCGCCCACGACTACTCCCGCCGCGGCAACCCGACGC
GTGATGTGGTGCAGCGCGCCTTAGCGGAGCTGGAAGGTGGCGCCGGCGCGGTGCTGACCAATACCGGTATGTCGGCGATC
CTGCTGGTGACGACGGTGTTCCTTAAGCCGGGCGATCTGCTGGTGGCGCCGCACGACTGCTACGGCGGCAGCTACCGTCT
GTTCGACAGCCTGGCGAAGCGCGGCTGTTATCGCGTCCAGTTCGTCGATCAAAATGATGAGCAGGCGCTGCGGGCGGCGT
TGGCGGAAAAACCGAAGCTGGTGCTGGTCGAAAGCCCAAGTAATCCATTGCTGCGGGTGGTGGATATTGCGAAAATCTGT
GGTCTGGCGCGTGAGGCAGGCGCGGTGAGCGTGGTGGACAACACCTTCCTGAGCCCGGCGCTGCAAAACCCGCTGGCGCT
GGGTGCCGATCTGGTGTTGCATTCCTGTACTAAATACCTGAATGGCCACTCCGATGTGGTTGCCGGGGTGGTGATTGCCA
ACGATCCGGCGACTGTCACCGAACTGGCATGGTGGGCGAATAATATTGGCGTCACCGGCGGCGCCTTCGACAGCTATTTG
TTGCTGCGCGGTCTGCGGACGCTGTCTCCGCGTATGGAAGTGGCGCAGCGTAATGCCCTGGCGATTGTTGAGTATCTGAA
AACCCAGCCGCTGGTGAAAAAGCTGTATCATCCGTCGCTGCCGGAAAACCAGGGGCATGAAATTGCGGCGCGTCAGCAAA
AAGGTTTTGGCGCAATGTTAAGCTTCGAGCTGGACGGTGACGAGCAGACGCTGCGCCGTTTCCTGAGCGGGCTGTCGCTG
TTTACACTGGCGGAATCGCTGGGGGGCGTTGAAAGCCTGATTTCCCATGCGGCAACGATGACGCATGCCGGCATGGCGCC
TGAAGCGCGTGCCGCCGCCGGAATTTCAGAAACGCTTCTGCGTATTTCAACCGGTATTGAAGATGGTGAAGATTTAATTG
CCGACCTGGAAAATGGCTTCCGGGCAGCAAACGAGGAATAA

Protein sequence :
MTRKQATIAVRSGLNDDEQYGCVVPPIHLSSTYNFTGFNEPRAHDYSRRGNPTRDVVQRALAELEGGAGAVLTNTGMSAI
LLVTTVFLKPGDLLVAPHDCYGGSYRLFDSLAKRGCYRVQFVDQNDEQALRAALAEKPKLVLVESPSNPLLRVVDIAKIC
GLAREAGAVSVVDNTFLSPALQNPLALGADLVLHSCTKYLNGHSDVVAGVVIANDPATVTELAWWANNIGVTGGAFDSYL
LLRGLRTLSPRMEVAQRNALAIVEYLKTQPLVKKLYHPSLPENQGHEIAARQQKGFGAMLSFELDGDEQTLRRFLSGLSL
FTLAESLGGVESLISHAATMTHAGMAPEARAAAGISETLLRISTGIEDGEDLIADLENGFRAANEE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-58 42
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-59 42