Gene Information

Name : hemC (KPK_5374)
Accession : YP_002241132.1
Strain : Klebsiella pneumoniae 342
Genome accession: NC_011283
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : -
Position : 5441530 - 5442471 bp
Length : 942 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGTTAGACAAAGTTTTGAAAATTGCCACACGGCAAAGCCCGCTTGCGCTATGGCAGGCGCAGTATGTTAAAGCGCGCCT
GGAACAAGCGCATCCAGGACTGAACGTCGAGCTGGTGCCGATGGTTACGCGCGGTGATGTCATCCTTGATACGCCCCTGG
CAAAGGTGGGCGGCAAGGGCTTATTTGTGAAAGAGTTAGAGCTCGCCATGCTCGAAGGGCGGGCCGATATCGCCGTCCAT
TCGATGAAAGATGTCCCGGTGGAATTCCCGGAGGGCCTGGGGTTGGTCACCATCTGCGAGCGCGACGATCCGCGCGACGC
GTTTGTTTCCAATCACTATGCCTCAATTGACGAACTGCCGGCCGGCAGCGTCGTTGGCACGTCAAGTTTACGCCGTCAGT
GCCAGCTGGCCGCCACCCGTCCAGACCTGGTGATCCGCTCTCTGCGCGGTAACGTCGGTACCCGGCTGAGTAAACTGGAT
AACGGTGAGTATGACGCCATTATCCTTGCCGCCGCCGGGTTGAAGCGCCTGAAACTGGAAGCGCGTATTCGCCAGCCGCT
GTCGCCGGAGCAATCCCTGCCGGCCGTCGGCCAGGGCGCGGTGGGTATCGAATGCCGTCTTGACGATGCATGGACCCAGG
CGCTGTTAGCGCCCCTCAACCATGCGGAAACCGCAGTACGCGTGCGCGCCGAACGGGCGATGAACACCCGCCTCGAAGGC
GGTTGTCAGGTGCCAATTGGCAGCTATGCGGAACTCGTCAACGGCGAACTGTGGCTGCGGGCGCTGGTTGGCGCCCCGGA
TGGTTCGCAGATGGTACGCGGCGAACGGCGCGGGCCAGCAGAGCAGGCCGAAGCGCTCGGCATCTCGCTGGCGGAAGAGC
TCCTGGATAACGGCGCCCGCGACATTCTCGCGGCAGTTTATGATGGAGAAGCCCCACGATGA

Protein sequence :
MLDKVLKIATRQSPLALWQAQYVKARLEQAHPGLNVELVPMVTRGDVILDTPLAKVGGKGLFVKELELAMLEGRADIAVH
SMKDVPVEFPEGLGLVTICERDDPRDAFVSNHYASIDELPAGSVVGTSSLRRQCQLAATRPDLVIRSLRGNVGTRLSKLD
NGEYDAIILAAAGLKRLKLEARIRQPLSPEQSLPAVGQGAVGIECRLDDAWTQALLAPLNHAETAVRVRAERAMNTRLEG
GCQVPIGSYAELVNGELWLRALVGAPDGSQMVRGERRGPAEQAEALGISLAEELLDNGARDILAAVYDGEAPR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 4e-83 63
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 4e-83 63