Gene Information

Name : alr (KPK_5235)
Accession : YP_002241006.1
Strain : Klebsiella pneumoniae 342
Genome accession: NC_011283
Putative virulence/resistance : Unknown
Product : alanine racemase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0787
EC number : -
Position : 5291099 - 5292178 bp
Length : 1080 bp
Strand : -
Note : converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer

DNA sequence :
ATGCAAGCGGCAACTGTAGTTATCAACCGCCGCGCTCTGCGACACAACCTGCAACGTTTGCGTGACCTGGCGCCTGCCAG
CAAACTGGTTGCGGTGGTGAAAGCGAACGCCTACGGACACGGCCTCCTTGAGACCGCGCGAACGCTGACCGACGCCGACG
CCTTTGGCGTCGCCCGCCTGGAAGAGGCGCTGCGCCTGCGAGCAGGAGGCATCGCCCAGCCGATCCTCCTGCTGGAAGGC
TTTTTTGCTGCGGAAGACCTGGCGGTGATCGCCGCCCAGCGCCTGCATACGGCGGTGCATAGCCCCGAACAGCTGGCGGC
GCTGGAGCAAGCCGATCTCCCCGAGCCGGTAACCGTGTGGATGAAGCTGGATACCGGCATGCATCGCTTAGGGGTGCGCC
CGGAGGAAGCCGAGGCGTTTTATCAGCGTCTGAGCCAGTGTAAAAACGTCCGCCAGCCGGTGAACGTGGTGAGCCATTTC
GCCCGCGCCGATGAGCCGACCTGCGGCGCCACCGAACGCCAGCTGGATATCTTCACCACCTTTACCGAAGGCAAACCGGG
GCTGCGCTCTATCGCCGCCTCGGGCGGCATTCTGCTGTGGCCGCAATCGCATTACGACTGGGTGCGCCCCGGGATTATCC
TGTATGGCGTGTCGCCGCTGGACGATCGCTCCACCGGGAAAGATTTTGGCTGCCAGCCGGTGATGACCCTGACGTCCAGC
CTGATTGCGGTGCGCGAGCATAAAGCAGGGGAGCCCGTCGGCTACGGCGGCACCTGGATCAGCGAACGCGATACCCGTCT
CGGCGTGGTGGCGATGGGCTATGGCGACGGTTATCCGCGCGCCGCGCCGTCGGGCACGCCGGTGCTGGTCAATGGCCGGG
AAGTGCCGATTGTCGGCCGGGTAGCGATGGATATGATCTGCGTTGACCTCGGACCGCAGGCCCAGGATAAAGCCGGCGAC
GCGGTAGTGCTGTGGGGAGAGGGACTCCCGGTAGAGCGCATCGCCGAGATAACGAAAGTGAGTGCTTACGAACTTATTAC
GCGACTGACCTCCCGCGTCGCCATGAAATACCTCGACTAA

Protein sequence :
MQAATVVINRRALRHNLQRLRDLAPASKLVAVVKANAYGHGLLETARTLTDADAFGVARLEEALRLRAGGIAQPILLLEG
FFAAEDLAVIAAQRLHTAVHSPEQLAALEQADLPEPVTVWMKLDTGMHRLGVRPEEAEAFYQRLSQCKNVRQPVNVVSHF
ARADEPTCGATERQLDIFTTFTEGKPGLRSIAASGGILLWPQSHYDWVRPGIILYGVSPLDDRSTGKDFGCQPVMTLTSS
LIAVREHKAGEPVGYGGTWISERDTRLGVVAMGYGDGYPRAAPSGTPVLVNGREVPIVGRVAMDMICVDLGPQAQDKAGD
AVVLWGEGLPVERIAEITKVSAYELITRLTSRVAMKYLD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dadX AAC61705.1 alanine racemase Not tested PAI I CFT073 Protein 4e-59 44