Gene Information

Name : KPK_5207 (KPK_5207)
Accession : YP_002240979.1
Strain : Klebsiella pneumoniae 342
Genome accession: NC_011283
Putative virulence/resistance : Virulence
Product : cyclic diguanylate phosphodiesterase (EAL) domain-containing protein
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG4943
EC number : -
Position : 5262221 - 5263825 bp
Length : 1605 bp
Strand : -
Note : Similar to Escherichia coli yjcC; identified by match to protein family HMM PF00563

DNA sequence :
ATGGCTGACAGTGCGCCGCATAAGGCGCTCAGACTTGTCGGAATGGGGCTGGTTATTTTATTGCCGGTGATGTTGGCATT
GTGGTTTGCCCAGCTGCGGGCCAAAGCCGAAACCATTGATCAATTGCACTCATTTTCGCAGCTGGCGCTGCAAAAAACAG
AAATGGTCATCCGGGAAGCGGATCAGGCGCGGTTTAAAGCCAGCCAGTATCGTGGTGAGCTATGCTCAGCGGAGCACCAG
CGTTATTTACTGCATATTGTTCGCGGTCTGCTGTATGTAGAAGATCTGATCTACGCCAACGGTCAGCGCTTTATCTGTTC
AACGTCCGCTCATCCCGAGACCGGCTGGCGGATGCCCGCGGCGAATTACACCAAAAAGCCGGATGTGGCGATTTACTACT
ATCGGGATACGCCGTTTTACCCGGGCTTTGCCATGAATTATATGCAGAAGGGGCCCTATGTGGTGGTGGTCAACCCCTAC
TCGTTCAGCTCGGTGATTGCCAGCGACCGCGATTTAGCCTATGGCGTTTTCGATACTAAAACCAACCTCTTTTTCTCGCT
GAGTAATAATGTTGAGCCCGCCGAACTCCAGGCGTTAATTCGCGAAGGCGATGCTTTTTTTAATCAGAATGGTCGGGTGT
ATACGATAGCCCGCTCCGCTATCCGGCCGATCGCGGTCATCATGTCCACCTCCCGGGCCAGCTACTATCACAACTTCTGT
GACCAGGCGAGCCTGACGCTGCCGCTGGGGATCATTTGCAGTATTTTACTGGTGCTGGTGTGGACACGAACCCGCCGCCA
GTATCACTCGCCGCGCAATATGCTACAGCGGGCTCTGAGCTGCCGCCAGCTGCGGCTGCACTACCAGCCGATTATCGATA
TTAAAAATAACCGCTGCGTCGGGGCGGAGGCGCTACTGCGATGGCCGGGGTTTGATGGCCCGGTGATGAACCCGGCGGAG
TTTATCCCGCTGGCGGAAAATGAAGGCATGATTGCCCAGATCACGGACTACGTGGTGGACGAGTTGTTTTATGAAATGGG
TGAGTTTCTTGCCAGCCATCCGCAGCTGTATGTGGCGATCAATCTCTCTGCGTCCGATTTCCACTCGGCGCGGCTGATTT
CCCAGATCAGTGAGAAAGCGCACAGCTATGCGGTCTGCATCGGACAGATCAAAATCGAAGTGACCGAGCGCGGGTTTATC
GACGTGGCGAAAACGACGCCGGTGATCCAGGCGTTCCGCGAAGCAGGCTATGAGATTGCGATCGATGATTTTGGTACCGG
CTACTCGAATCTGCATAATCTGCACGCGCTGAATGTCGATATCCTCAAAATCGATAAAACCTTCGTTGATACGCTGACCA
CCAACAACACCAGCCATCTGATCGCTGAGCACATCATCGAGATGGCGCGCGGGCTGCGTTTAAAAACTATCGCGGAAGGG
GTGGAGACCCCGGAGCAGGTAAGCTGGCTCTACAAGCGCGGCGTGCAATTTTGTCAGGGCTGGCTGTTTGCGAAAGCCAT
GCCGGCGCGGGAGTTTATGCAGTGGTTAGCGAATGCTCCCACGCCCATAAGCAGGCCTCAGCCGCCGCGTCACGCGGAGA
TCTGA

Protein sequence :
MADSAPHKALRLVGMGLVILLPVMLALWFAQLRAKAETIDQLHSFSQLALQKTEMVIREADQARFKASQYRGELCSAEHQ
RYLLHIVRGLLYVEDLIYANGQRFICSTSAHPETGWRMPAANYTKKPDVAIYYYRDTPFYPGFAMNYMQKGPYVVVVNPY
SFSSVIASDRDLAYGVFDTKTNLFFSLSNNVEPAELQALIREGDAFFNQNGRVYTIARSAIRPIAVIMSTSRASYYHNFC
DQASLTLPLGIICSILLVLVWTRTRRQYHSPRNMLQRALSCRQLRLHYQPIIDIKNNRCVGAEALLRWPGFDGPVMNPAE
FIPLAENEGMIAQITDYVVDELFYEMGEFLASHPQLYVAINLSASDFHSARLISQISEKAHSYAVCIGQIKIEVTERGFI
DVAKTTPVIQAFREAGYEIAIDDFGTGYSNLHNLHALNVDILKIDKTFVDTLTTNNTSHLIAEHIIEMARGLRLKTIAEG
VETPEQVSWLYKRGVQFCQGWLFAKAMPAREFMQWLANAPTPISRPQPPRHAEI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
yjcC YP_219130.1 diguanylate cyclase/phosphodiesterase Not tested SPI-4 Protein 2e-171 62

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
KPK_5207 YP_002240979.1 cyclic diguanylate phosphodiesterase (EAL) domain-containing protein VFG0584 Protein 1e-171 62