Gene Information

Name : actP (KPK_5193)
Accession : YP_002240964.1
Strain : Klebsiella pneumoniae 342
Genome accession: NC_011283
Putative virulence/resistance : Resistance
Product : acetate permease
Function : -
COG functional category : R : General function prediction only
COG ID : COG4147
EC number : -
Position : 5246894 - 5248549 bp
Length : 1656 bp
Strand : +
Note : member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake

DNA sequence :
ATGATCAAGAGAGTCCTGACGGCGCTCGCCGCCACGCTGCTACCCCTCGGCGCTCACGCGGCAGACGCCATTACCGGCGC
GGTACAGCGCCAGCCGACCAACTGGCAGGCGATTGTCATGTTCCTGATTTTCGTCGCCCTGACGCTTTACATCACCTACT
GGGCCTCAAAACGGGTACGTTCGCGCAGCGATTATTATACCGCCGGCGGCAATATTACCGGCTTCCAGAACGGGCTGGCG
ATTGCCGGCGACTTTATGTCAGCGGCTTCTTTCCTCGGTATCTCCGCGCTGGTGTATACCTCAGGCTACGACGGCCTGAT
CTACTCGCTGGGCTTTCTCGTCGGCTGGCCGATTATCCTGTTTCTGATCGCCGAACGACTGCGCAACCTTGGCCGCTATA
CCTTTGCTGACGTCGCTTCATACCGCCTGAAGCAGGGGCCGATCCGCACCCTCTCCGCCTGCGGATCGCTGGTGGTGGTG
GCGCTGTATCTGATCGCGCAGATGGTGGGCGCCGGCAAGCTGATCCAGCTGCTGTTCGGCCTCAATTACCATGTCGCCGT
GGTGCTGGTTGGCGTGCTGATGGTGCTCTATGTCCTGTTCGGCGGCATGCTGGCAACCACCTGGGTGCAGATTATTAAAG
CGGTTCTGCTGCTGTGCGGCGCCAGCTTTATGGCCTTTATGGTCATGAAGCACGTCGGCTTCAGCTTCAATAACCTGTTT
ACCGAGGCGATGGCCGTCCATCCGAAAGGGGCGGCGATTATGAGTCCCGGCGGACTGGTGAAAGATCCGATATCCGCGCT
CTCTCTGGGTCTGGGTCTGATGTTCGGTACCGCCGGCCTGCCGCATATTCTGATGCGCTTCTTTACCGTGAGCGATGCCA
AAGAAGCGCGTAAAAGCGTCTTCTACGCCACCGGTTTTATGGGCTATTTCTATATCCTGACCTTTATTATCGGCTTCGGC
GCCATCATGCTGGTCGGCGCGAACCCGGCGTTTAAAGACGCGGCCGGACAGCTTATCGGCGGCAATAACATGGCGGCGGT
GCATCTGGCGGATGCGGTGGGGGGCAATCTGTTCCTCGGCTTTATCTCCGCGGTCGCTTTCGCCACTATCCTGGCGGTGG
TGGCTGGCCTGACGCTCGCCGGCGCCTCAGCGGTGTCGCACGACCTGTACGCCAACGTCTTCCGCAAGGGCGCGACCGAG
CGTCAGGAGCTGAAGGTCTCCAAGATCACCGTGCTGATCCTCGGGGTGGTGGCCATTCTGCTGGGTATTCTGTTTGAAAA
TCAGAACATCGCTTTCATGGTCGGCCTGGCCTTCTCCATTGCCGCCAGCTGTAACTTCCCGATTATTCTGCTGTCGATGT
ACTGGTCGAAGCTGACCACCCGCGGCGCGATGGTCGGCGGCTGGCTGGGACTGCTGACCGCGGTCATTCTGATGATCCTC
GGCCCGACCATTTGGGTGCAGATCCTCGGCCATGAGAAAGCGCTGTTCCCGTATGAATATCCGGCGCTGTTCTCCATCGC
CATCGCGTTCATCGGTATCTGGGTCTTCTCCGCCACCGATAACTCACCGGAAGGGATGCGCGAGCGCGAGCAGTTCCGCG
CCCAGTTTATCCGTTCGCAAACCGGGATCGGTATCGAACGCGGCCAGGCGCACTAA

Protein sequence :
MIKRVLTALAATLLPLGAHAADAITGAVQRQPTNWQAIVMFLIFVALTLYITYWASKRVRSRSDYYTAGGNITGFQNGLA
IAGDFMSAASFLGISALVYTSGYDGLIYSLGFLVGWPIILFLIAERLRNLGRYTFADVASYRLKQGPIRTLSACGSLVVV
ALYLIAQMVGAGKLIQLLFGLNYHVAVVLVGVLMVLYVLFGGMLATTWVQIIKAVLLLCGASFMAFMVMKHVGFSFNNLF
TEAMAVHPKGAAIMSPGGLVKDPISALSLGLGLMFGTAGLPHILMRFFTVSDAKEARKSVFYATGFMGYFYILTFIIGFG
AIMLVGANPAFKDAAGQLIGGNNMAAVHLADAVGGNLFLGFISAVAFATILAVVAGLTLAGASAVSHDLYANVFRKGATE
RQELKVSKITVLILGVVAILLGILFENQNIAFMVGLAFSIAASCNFPIILLSMYWSKLTTRGAMVGGWLGLLTAVILMIL
GPTIWVQILGHEKALFPYEYPALFSIAIAFIGIWVFSATDNSPEGMREREQFRAQFIRSQTGIGIERGQAH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AAK01502.1 putative amino acid transport protein Not tested PAGI-1 Protein 3e-124 59
cur_1523 YP_001800917.1 transporter Not tested Not named Protein 5e-69 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
actP YP_002240964.1 acetate permease BAC0564 Protein 0.0 92
actP YP_002240964.1 acetate permease BAC0570 Protein 1e-136 65