Gene Information

Name : pepA (KPK_5003)
Accession : YP_002240779.1
Strain : Klebsiella pneumoniae 342
Genome accession: NC_011283
Putative virulence/resistance : Unknown
Product : leucyl aminopeptidase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0260
EC number : -
Position : 5051462 - 5052973 bp
Length : 1512 bp
Strand : +
Note : catalyzes the removal of N-terminal amino acids preferably leucine from various peptides

DNA sequence :
ATGGAGTTCAGTGTAAAAAGCGGTAGCCCGGAGAAGCAACGGAGCGCCTGTATCGTGGTCGGCGTCTTTGAACCACGTCG
CCTCTCCCCCATCGCCGAACAACTCGATAAAATCAGCGACGGCTACATCAGCGCCCTGCTGCGTCGCGGCGAGCTGGAAG
GCAAACCTGGCCAGACGTTATTGCTGCACCATGTGCCAAACATTCTGTCTGAGCGCATTCTGCTGATTGGCTGCGGCAAA
GAGCGCGAGCTGGATGAACGTCAGTATAAGCAGGTCATCCAGAAAACCATCAATACCCTGAATGATACCGGTTCAATGGA
AGCCGTCTGCTTCCTGACCGAGCTGCACGTCAAGGGCCGCAACAACTACTGGAAAGTTCGCCAGGCCGTTGAAACCGCCA
AAGAGACGCTGTACAGCTTCGATCAGTTGAAGACCAACAAAAGCGAGCCGCGTCGCCCGCTGCGTAAAATGGTCTTTAAC
GTGCCGACCCGTCGCGAGCTGACCAGCGGAGAACGCGCCATTCAGCATGGCCTGGCGATCGCCGCCGGCATCAAAGCGGC
GAAAGATCTTGGCAACATGCCGCCGAACATCTGTAACGCCGCCTATCTGGCTTCCCAGGCGCGTCAGCTGGCCGATACCT
ACAGCAAGAACGTCATTACCCGCGTGATCGGCGAACAGCAGATGCGCGAGCTGGGGATGAACTCCTATCTCGCCGTCGGC
AACGGCTCGCAGAACGAGTCGCTGATGTCGGTCATCGAGTATAAAGGCAACCCGTCTGAGGACGCGCGCCCTATCGTGCT
GGTCGGTAAAGGCCTGACCTTCGACTCCGGCGGCATCTCCATCAAGCCTGCCGAAGGCATGGACGAGATGAAGTACGACA
TGTGCGGCGCCGCGGCGGTGTACGGCGTGATGCGGATGGTTGCCGAGCTGCAGCTGCCGCTGAACGTCATCGGCGTGCTG
GCGGGCTGTGAAAACATGCCTGGCGGTCGCGCCTATCGTCCGGGTGACGTCCTGACCACCATGTCCGGCCAGACGGTGGA
AGTCCTGAACACCGACGCCGAAGGCCGCCTGGTGCTGTGCGACGTCCTGACCTACGTTGAGCGTTTCGAACCGGAAGCGG
TTATCGACGTCGCGACGCTGACCGGCGCCTGCGTGATTGCCCTCGGCCATCACATCACCGGCCTGATGTCGAACCATAAC
CCGCTGGCTCATGAGCTGATCGGCGCCTCCGAACTGGCGGGCGACCGCGCCTGGCGTCTGCCGCTGGCCGACGAGTTCCA
GGATCAGCTGGAGTCCAATTTTGCCGATATGGCGAACATCGGCGGTCGTCCTGGCGGCGCAATTACCGCCGGCTGCTTCC
TGTCGCGCTTTACCCGTAAGTACAACTGGGCGCACCTCGACATCGCCGGTACCGCCTGGCGTTCCGGTAAGGCCAAAGGC
GCCACCGGTCGTCCGGTCGCCCTGCTGTCGCAGTTCCTGCTCAATCGTGCGGGTTTTAACGGCGAAGAGTGA

Protein sequence :
MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISDGYISALLRRGELEGKPGQTLLLHHVPNILSERILLIGCGK
ERELDERQYKQVIQKTINTLNDTGSMEAVCFLTELHVKGRNNYWKVRQAVETAKETLYSFDQLKTNKSEPRRPLRKMVFN
VPTRRELTSGERAIQHGLAIAAGIKAAKDLGNMPPNICNAAYLASQARQLADTYSKNVITRVIGEQQMRELGMNSYLAVG
NGSQNESLMSVIEYKGNPSEDARPIVLVGKGLTFDSGGISIKPAEGMDEMKYDMCGAAAVYGVMRMVAELQLPLNVIGVL
AGCENMPGGRAYRPGDVLTTMSGQTVEVLNTDAEGRLVLCDVLTYVERFEPEAVIDVATLTGACVIALGHHITGLMSNHN
PLAHELIGASELAGDRAWRLPLADEFQDQLESNFADMANIGGRPGGAITAGCFLSRFTRKYNWAHLDIAGTAWRSGKAKG
ATGRPVALLSQFLLNRAGFNGEE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00295 YP_008207760.1 Leucyl aminopeptidase Not tested AbaR25 Protein 2e-88 54
BJAB0868_00299 YP_008211625.1 Leucyl aminopeptidase Not tested AbaR26 Protein 2e-88 54