Gene Information

Name : KPK_4978 (KPK_4978)
Accession : YP_002240755.1
Strain : Klebsiella pneumoniae 342
Genome accession: NC_011283
Putative virulence/resistance : Unknown
Product : phage integrase family site-specific recombinase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0582
EC number : -
Position : 5023932 - 5025206 bp
Length : 1275 bp
Strand : -
Note : identified by match to protein family HMM PF00589

DNA sequence : 
ATGGCTCTGAGTGATGTGAAGGTTCGTTCGGCTAAGCCTGAAGCAAAAGCCTATAAACTAACTGACGGTGAAGGCATGGT
TTTGCTGGTTCACCCTAACGGCTCCAAATACTGGCGGCTACGTTATCGCTTCGGTGGTAAAGAGAAGATGTTGGCGCTGG
GGAAATACCCTGAAGTGTCGTTGGCGGATGCCCGGGCACGCCGGGATGAGGCCCGTAAGCTATTAGCTAATGGTGTCGAT
CCTAGTGAGAACAAGAAGGCCGTTAAGGTAGAGCAGGAGCAAGAGGCGATAACGTTTGAGGTAGTGGCCAGAGACTGGCA
TGCCAGTAATCAGAAGTGGTCGGCATCGCATAGCGCTCGTGTTTTGAAAAGTCTGGAGGATAATCTCTTCGCTGCCATCG
GTAAGCGGAACATTGCTGACCTCAAGACACGGGATCTGCTTGTCCCCATCAAAGCGGTGGAGTCGTCCGGCCGTCTCGAA
GTTGCGGCTCGTTTGCAACAGCGAACAACCGCGATTATGCGGTTTGCCGTTCAGAGCGGCTTAATCGATTACAACCCAGC
GCAAGAGATTGCCGGTGCGGTGGCTACGGCGAAAAGACAGCACCGTGCTGCTCTGGAGCTTAACCGCATTCCTGAATTGC
TTCACCGCATCGATCACTATTCCGGAAGGCTATTAACCCAACTTGCTGTCGAACTTACCTTGTTAGTTTTTATACGTTCA
AGCGAGCTGCGATTTGCCCGCTGGTCAGAAGTGGATTTTGAAACGGCCATGTGGACGATCCCCGGTGAGCGTGAACTGCT
GGACGGTGTTAAACATTCACAGCGTGGTTCAAAGATGCGGACGCCCCATCTTGTTCCCTTATCGCGTCAGGCCTTAGCTA
TTCTGGAAAAGATCAAAAGCATGAATGGGAATCGAGAGCTGATTTTCGTAGGCGATCACGATCCCCGTAAGCCGATGAGT
GAGAACACGGTGAACAAGGCGCTGAGAGTGATGGGTTATGACACGAAAACGGAGGTCTGTGGGCATGGATTCAGGACGAT
GGCTTGTAGCTCATTGATTGAATCGGGTTTGTGGTCGAGGGATGCAGTGGAGCGGCAGATGAGCCATCAGGAACGTAGCT
CTGTTCGGGCAGCTTACATTCATAAGGCGGAGCATCTCGGGGAGCGTAGGTTGATGCTGCAGTGGTGGGCGGATTATCTG
GATGCTAATCGAGAAAAAATCTTTTCTCCTTTTGATTATGCAAAAATCAATAACCCATTAAGCCAGAATAAGTAA

Protein sequence : 
MALSDVKVRSAKPEAKAYKLTDGEGMVLLVHPNGSKYWRLRYRFGGKEKMLALGKYPEVSLADARARRDEARKLLANGVD
PSENKKAVKVEQEQEAITFEVVARDWHASNQKWSASHSARVLKSLEDNLFAAIGKRNIADLKTRDLLVPIKAVESSGRLE
VAARLQQRTTAIMRFAVQSGLIDYNPAQEIAGAVATAKRQHRAALELNRIPELLHRIDHYSGRLLTQLAVELTLLVFIRS
SELRFARWSEVDFETAMWTIPGERELLDGVKHSQRGSKMRTPHLVPLSRQALAILEKIKSMNGNRELIFVGDHDPRKPMS
ENTVNKALRVMGYDTKTEVCGHGFRTMACSSLIESGLWSRDAVERQMSHQERSSVRAAYIHKAEHLGERRLMLQWWADYL
DANREKIFSPFDYAKINNPLSQNK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
intB CAD42017.1 bacteriophage P4 integrase Not tested PAI II 536 Protein 3e-142 80
c5216 NP_757064.1 prophage P4 integrase Not tested PAI II CFT073 Protein 1e-140 71
ECO111_3718 YP_003236059.1 putative integrase Not tested LEE Protein 5e-140 70
int CAC81896.1 integrase Not tested LEE II Protein 3e-131 70
int-phe AAL60261.1 Int-phe Not tested LEE Protein 6e-141 70
int AAT48697.1 CP4-like integrase Not tested PAI I 4787 Protein 1e-139 70
Z4313 NP_289539.1 pathogenicity island integrase Not tested OI-122 Protein 4e-140 70
int AAL51003.1 CP4-like integrase Not tested LEE Protein 4e-140 70
int AAK16198.1 Int Not tested PAI-I AL862 Protein 1e-140 70
int ADD91747.1 P4 integrase Not tested PAI-I AL862 Protein 1e-140 70
int-phe AAL57571.1 CP4-like integrase Not tested LEE Protein 6e-141 70
ECO103_3550 YP_003223418.1 integrase Not tested LEE Protein 9e-141 70
ECUMN_3322 YP_002414004.1 integrase Not tested Not named Protein 1e-137 70
int AAL51028.1 CP4-like integrase Not tested LEE Protein 6e-141 70
ECO26_5300 YP_003232178.1 integrase Not tested LEE Protein 9e-141 70
c3556 NP_755431.1 prophage P4 integrase Not tested PAI I CFT073 Protein 3e-139 70
S4822 NP_838459.1 P4-type integrase Not tested SHI-1 Protein 4e-140 70
ORF_1 AAZ04412.1 phage integrase Not tested PAI I APEC-O1 Protein 2e-140 70
SF2964 NP_708738.1 P4-type integrase Not tested SHI-1 Protein 4e-140 70
APECO1_3534 YP_854214.1 P4-like integrase Not tested PAI I APEC-O1 Protein 3e-140 70
int AAK00456.1 Int Not tested SHI-1 Protein 2e-130 70
intP4 CAE85151.1 CP4 integrase protein Not tested PAI V 536 Protein 5e-140 70
SESS1296_03598 AFO66301.1 bacteriophage integrase Not tested SESS LEE Protein 4e-122 63
SESS1635_03816 AFO66367.1 bacteriophage integrase Not tested SESS LEE Protein 4e-122 63
APECO1_1051 YP_853069.1 phage integrase Not tested PAI IV APEC-O1 Protein 1e-77 57
STY4821 NP_458899.1 integrase Not tested SPI-10 Protein 9e-110 57
intB AAD37509.1 P4-like integrase Not tested PAI IV 536 Protein 7e-90 56
int NP_458759.1 bacteriophage integrase Not tested SPI-7 Protein 4e-105 55
int NP_807963.1 bacteriophage integrase Not tested SPI-7 Protein 4e-105 55
y2393 NP_669700.1 prophage integrase Not tested HPI Protein 1e-103 55
int2 NP_993013.1 integrase Not tested HPI Protein 1e-103 55
int CAA08754.1 integrase Not tested HPI Protein 4e-104 55
int CAA21384.1 - Not tested HPI Protein 1e-103 55
int CAB59974.1 integrase Not tested HPI Protein 4e-104 55
int YP_002346908.1 integrase Not tested HPI Protein 1e-103 55
unnamed AAD17660.1 unknown Not tested HPI Protein 9e-101 54
unnamed ABR13507.1 phage integrase Not tested PAGI-6 Protein 2e-97 53
int AAC31482.1 CP4-like integrase Not tested LEE Protein 3e-78 43
int ACU09430.1 integrase Not tested LEE Protein 3e-78 43
intL NP_290239.1 integrase for prophage 933L and the LEE pathogenicity island Not tested LEE Protein 4e-78 43
ECs4534 NP_312561.1 integrase Not tested LEE Protein 4e-78 43
int AAD44730.1 Int Not tested SHI-2 Protein 2e-79 43
int CAC39282.1 integrase Not tested LPA Protein 4e-80 43
aec33 AAW51716.1 Int Not tested AGI-3 Protein 4e-80 43
int AAD54663.1 Sai integrase Not tested SHI-2 Protein 5e-78 43
S4835 NP_839238.1 integrase Not tested SHI-2 Protein 6e-78 43
SF3698 NP_709437.1 integrase Not tested SHI-2 Protein 6e-78 43
unnamed AFX83955.1 integrase Not tested SE-PAI Protein 3e-66 41
ESA_03025 YP_001439090.1 hypothetical protein Not tested Not named Protein 2e-67 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
KPK_4978 YP_002240755.1 phage integrase family site-specific recombinase VFG1536 Protein 2e-142 80
KPK_4978 YP_002240755.1 phage integrase family site-specific recombinase VFG1693 Protein 1e-139 70
KPK_4978 YP_002240755.1 phage integrase family site-specific recombinase VFG0626 Protein 2e-140 70
KPK_4978 YP_002240755.1 phage integrase family site-specific recombinase VFG0783 Protein 2e-78 43
KPK_4978 YP_002240755.1 phage integrase family site-specific recombinase VFG0598 Protein 3e-78 43