Gene Information

Name : hpaE (KPK_4833)
Accession : YP_002240619.1
Strain : Klebsiella pneumoniae 342
Genome accession: NC_011283
Putative virulence/resistance : Unknown
Product : 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 4881643 - 4883109 bp
Length : 1467 bp
Strand : +
Note : identified by similarity to GB:CAA86041.1; match to protein family HMM PF00171; match to protein family HMM TIGR02299

DNA sequence :
ATGAAAAAGATTAACCATTGGATCAACGGTAAAAACGTTGCCGGCGCAGACTATTTTCATACCACCAACCCGGCCACGGG
CGAGGTACTGGCTGAAGTCGCCTCCGGCGGTGAAGCCGAAGTTCACCAGGCGGTAGCGGCGGCGAAAGCGGCCTTCCCGA
AGTGGGCTAACCTGCCGATGAAAGAGCGCGCGCGCCTGATGCGCCGCCTGGGGGATCTGATCGATCAGAACGTCCCGGAG
ATCGCGGCGATGGAAACCGCCGATACCGGCCTGCCTATCCACCAGACCAAAAACGTGCTGATCCCGCGGGCGTCGCATAA
CTTCGAATTTTTCGCCGAAGTGTGCCAGCAGATGAACGGCAAGACCTATCCGGTCGATGACAAGATGCTCAACTATACCC
TCGTGCAGCCGGTTGGCGTGTGCGCGCTGGTGTCGCCGTGGAACGTGCCGTTCATGACCGCCACCTGGAAGGTCGCGCCG
TGTCTCGCACTGGGGAATACCGCGGTGCTGAAAATGTCCGAGCTGTCGCCGCTGACCGCCGATCGTCTGGGCGAGCTGGC
GCTGGAAGCCGGGATCCCGGCTGGCGTGCTCAACGTGGTGCAGGGCTATGGCGCCACCGCCGGCGACGCGCTGGTGCGCC
ATCATGATGTGCGCGCCGTCTCGTTCACCGGCGGCACCGCCACCGGCCGCAACATCATGAAGAACGCCGGTCTGAAAAAG
TACTCTATGGAGCTCGGCGGAAAATCGCCGGTGCTGATTTTTGAAGACGCCGATATTGAGCGCGCACTCGACGCCGCGCT
GTTCACCATTTTCTCGATCAACGGCGAACGCTGCACCGCCGGTTCGCGCATTTTCATTCAGCAGAGTATTTATCCGGAGT
TCGTCAAGCGCTTCGCCGAGCGCGCCAACCGCCTGCGCGTGGGCGATCCGACCGATCCGAATACCCAGGTCGGCGCGCTG
ATTAGCAAGCAGCACTGGGAGAAAGTGTCCGGCTACATTCGCCTCGGCATCGAAGAGGGCGCCACCCTGCTGGCCGGCGG
CGCGGATAAACCGTCCGACCTGCCGGCGCATCTGAAAGCCGGCAACTTCCTGCGCCCGACGGTACTGGCGGATGTCGACA
ACCGCATGCGCGTCGCCCAGGAAGAGATTTTTGGCCCGGTCGCCTGCCTGCTGCCGTTCAAAGACGAAGCGGAAGGGCTG
CGCCTGGCGAACGATGTGGAATACGGCCTGGCGTCGTATATCTGGACCCAGGACGTCAGCAAAGTGCTGCGTCTGGCGCG
CGGTATTGAAGCCGGGATGGTGTTCGTCAACACCCAGAACGTGCGCGACCTGCGTCAGCCGTTCGGCGGCGTGAAGGCCT
CCGGCACCGGCCGCGAAGGCGGCGAGTACAGCTTTGAAGTGTTCGCCGAAATGAAAAACGTCTGCATCTCGATGGGCGAC
CATCCGATCCCGAAATGGGGAGTCTGA

Protein sequence :
MKKINHWINGKNVAGADYFHTTNPATGEVLAEVASGGEAEVHQAVAAAKAAFPKWANLPMKERARLMRRLGDLIDQNVPE
IAAMETADTGLPIHQTKNVLIPRASHNFEFFAEVCQQMNGKTYPVDDKMLNYTLVQPVGVCALVSPWNVPFMTATWKVAP
CLALGNTAVLKMSELSPLTADRLGELALEAGIPAGVLNVVQGYGATAGDALVRHHDVRAVSFTGGTATGRNIMKNAGLKK
YSMELGGKSPVLIFEDADIERALDAALFTIFSINGERCTAGSRIFIQQSIYPEFVKRFAERANRLRVGDPTDPNTQVGAL
ISKQHWEKVSGYIRLGIEEGATLLAGGADKPSDLPAHLKAGNFLRPTVLADVDNRMRVAQEEIFGPVACLLPFKDEAEGL
RLANDVEYGLASYIWTQDVSKVLRLARGIEAGMVFVNTQNVRDLRQPFGGVKASGTGREGGEYSFEVFAEMKNVCISMGD
HPIPKWGV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hpaE AAO17179.1 HpaE Not tested tcd island Protein 0.0 93
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 4e-69 42