Gene Information

Name : ldcC (KPK_4534)
Accession : YP_002240326.1
Strain : Klebsiella pneumoniae 342
Genome accession: NC_011283
Putative virulence/resistance : Virulence
Product : lysine decarboxylase, constitutive
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG1982
EC number : -
Position : 4558523 - 4560676 bp
Length : 2154 bp
Strand : -
Note : identified by similarity to SP:P52095; match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711

DNA sequence :
GTGAATATTATCGCCATCATGGGGCCTCACGGCGTCTACCACAAAGACGAGCCGATCAAAGAACTGGAAGCGGCGCTGCA
GCGCCAGGGCTTCCAGACCATCTGGCCGCAAAACAGCGCCGACCTGCTGCAGTTTATTGAGCACAACCCGCGCATCTGCG
GGGTGATCTTCGACTGGGATGAATACAGCGTCGATCTGTGCAGCGATATCAATCAGCTCAATGAATATCTGCCCCTGTAC
GCCTTTATTAATGCCCACTCGACGATGGACGTCAGCAGTCAGGATCTGCGTATGACGCTGTGGTTCTTCGAATATGCGCT
GGGACTCTCCGAAGAGATCGCCACCCGCATTGGGCAGTATACCCGCGAGTACCTGGACAATATCACCCCGCCGTTTACCC
GCGCGCTGTTTAACTATGTGCAGGAGGGGAAGTATACCTTTTGTACACCGGGCCATATGGGCGGTAGCGCCTATCAGAAA
AGCCCGGTGGGCTGCCTGTTCTATGATTTCTTTGGCGGAAATACGCTGAAGGCGGATGTCTCGATTTCGGTCACCGAGCT
GGGCTCCCTGCTGGATCATACCGGCCCGCATCTGGAGGCGGAGGAGTATATTGCCCGCGCCTTTGGCGCTGAACAGAGCT
ACATGGTGACCAATGGCACCTCGACGTCCAACAAAATTGTCGGTATGTACTCGGCGCCCGCCGGCAGCACGCTGCTGATT
GACCGTAACTGTCACAAATCACTGGCCCACCTGCTGATGATGAGCGATGTGGTTCCCTTGTGGCTGAAGCCGACCCGCAA
CGCGTTGGGGATCCTCGGCGGTATCCCCCGGCGCGAATTTACCCGCGACAGCATTCAGCAGAAAGTACGCGACACGGGCG
GGGCGCAGTGGCCCGTGCATGCGGTGATCACCAACTCCACCTACGATGGCCTGCTCTATAACACCACCTGGCTTAAGGAG
ACGCTCGACGTCCCGTCGATCCATTTCGATTCCGCCTGGGTGCCCTATACCCATTTCCATCCGATATATCAGGGGAAAAG
CGGCATGAGCGGGGAGCGGATCCCCGGAAAAGTCATCTTCGAGACGCAGTCGACGCATAAGATGCTGGCCGCGCTGTCGC
AGGCCTCGCTGATCCACATTAAGGGCAACTATGATGAAGAGACCTTTAATGAAGCCTTTATGATGCATACCTCGACGTCG
CCGAGCTATCCCATCGTCGCGTCGATTGAGACCGCGGCGGCGATGCTGCGCGGTAACTCCGGTAAGCGCCTGATCCAGCG
CTCCATTGAGCGAGCGCTGGATTTCCGCAAAGAGGTGCAGCGACTGCGCGAGGAGTCAGACGGCTGGTTCTTTGATATCT
GGCAGCCGGAAGCGGTGGATAAAGCCGAGTGCTGGCCGGTGGCGCCTGGCGAAGACTGGCACGGTTTCAAAGATGCCGAT
GCGGATCATATGTATCTCGATCCGGTGAAGGTCACCATTCTGACGCCGGGCATGGACGAGCAGGGGAATATGGATGAAGA
GGGGATCCCGGCGGCGCTGGTGGCGAAGTTCCTCGACGAGCGGGGCGTGGTGGTGGAAAAAACGGGCCCCTATAACCTGC
TGTTCCTGTTCAGCATCGGTATTGATAAAACCCGGGCGATGGGGCTGCTGCGCGGTCTGACCGAGTTCAAACGCGCCTAC
GATCTTAATCTGCGGGTGAAAAATATGTTGCCGGATCTGTACGCGGAAGATCCCGACTTCTACCGCAACATGCGGATCCA
GGATCTGGCACAGGGGATCCACCGCTTGATCCGTCAGCACCAGCTGCCGCAGCTGATGCTCAGCGCCTTTGACGTCCTGC
CGGAAATGAAAATGACGCCGCATCACGCCTGGCAGCGCCAGATTAAGGGTGAGGTGGAAACCATTGAACTGGAGAACCTG
GTCGGCCGGATTTCGGCCAACATGATCCTCCCTTATCCGCCGGGCGTACCGCTGCTGATGCCGGGAGAGATGATCACGGA
GGAGAGCCGGGCAGTGCTCGATTTCCTGCTGATGCTCTGCTCCATCGGCCGTCATTACCCGGGGTTTGAGACCGATATTC
ACGGGGCGAAGCGCGATGAGGACGGCGTGTATCGGGTACGAGTCTTAAAAAATGACGAAAGGCTTGCGCGTTAA

Protein sequence :
MNIIAIMGPHGVYHKDEPIKELEAALQRQGFQTIWPQNSADLLQFIEHNPRICGVIFDWDEYSVDLCSDINQLNEYLPLY
AFINAHSTMDVSSQDLRMTLWFFEYALGLSEEIATRIGQYTREYLDNITPPFTRALFNYVQEGKYTFCTPGHMGGSAYQK
SPVGCLFYDFFGGNTLKADVSISVTELGSLLDHTGPHLEAEEYIARAFGAEQSYMVTNGTSTSNKIVGMYSAPAGSTLLI
DRNCHKSLAHLLMMSDVVPLWLKPTRNALGILGGIPRREFTRDSIQQKVRDTGGAQWPVHAVITNSTYDGLLYNTTWLKE
TLDVPSIHFDSAWVPYTHFHPIYQGKSGMSGERIPGKVIFETQSTHKMLAALSQASLIHIKGNYDEETFNEAFMMHTSTS
PSYPIVASIETAAAMLRGNSGKRLIQRSIERALDFRKEVQRLREESDGWFFDIWQPEAVDKAECWPVAPGEDWHGFKDAD
ADHMYLDPVKVTILTPGMDEQGNMDEEGIPAALVAKFLDERGVVVEKTGPYNLLFLFSIGIDKTRAMGLLRGLTEFKRAY
DLNLRVKNMLPDLYAEDPDFYRNMRIQDLAQGIHRLIRQHQLPQLMLSAFDVLPEMKMTPHHAWQRQIKGEVETIELENL
VGRISANMILPYPPGVPLLMPGEMITEESRAVLDFLLMLCSIGRHYPGFETDIHGAKRDEDGVYRVRVLKNDERLAR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cadA NP_756988.1 lysine decarboxylase, inducible Not tested PAI II CFT073 Protein 0.0 70
unnamed CAD66195.1 putative cadaverin decarboxylase Virulence PAI III 536 Protein 0.0 63

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ldcC YP_002240326.1 lysine decarboxylase, constitutive VFG1670 Protein 0.0 63