Gene Information

Name : KPK_4426 (KPK_4426)
Accession : YP_002240225.1
Strain : Klebsiella pneumoniae 342
Genome accession: NC_011283
Putative virulence/resistance : Unknown
Product : phage integrase family site-specific recombinase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0582
EC number : -
Position : 4452425 - 4453639 bp
Length : 1215 bp
Strand : +
Note : identified by match to protein family HMM PF00589

DNA sequence :
ATGAAGCTCAATGCCAGACAGGTCGAGACTGCCAAGCCTAAAGATAAACCCTATAAGTTAGCAGATGGTGGGGGCATGTA
TCTGGAGGTGTTCCCTAACGGCACCAAAAGCTGGCGCATGAAATACCGTATCGCAGGTAAAGAAAAACGTGTGGTGTTTG
GTGTTTACCCGACCATTACCTTAGCGGATGCCAGAAGCAAAAGAGATGATGCTAAAAAGCTGCTGGTTAATGGCGTTGAT
CCGAGTGCGTTTAAGAAAGAAAGCAAACTAGCCCAAATCGAAGAAGTAAAAAACACCTTTCAGCAAATTGCGCTCGAATG
GCACAACATGAAAGTGAAGAAATGGTCTGCGGGATATGCCTCTGACATTCTTGAAGCCTTCAACAAAGATGTCTTCCCGT
TCATCGGTCAACGTCCTGTTGCAGACATCAAGCCGTTGGAATTGCTTAACGTGCTCAAAAAGATGGAAGAGCGAGGTGCG
ACTGAGAAAGCTAAGAAAGTACGTCAGCGGTGTGGTGAAGTGTTTCGCTACGCCATAGTTACAGGCAGAGCCGAGTATAA
CCCCGCACCAGATCTCACCAGTGCTATGCAGGGGCATGAGTCTAAACATTATCCATTCCTGACCATTGAGGAGCTTCCAG
CCTTTTTTAAAGCCCTTGCTGGCTACTCTGGTAGTGAGTTGGTAGTGTTAGCCGCCCGACTAATGATCATCACTGGTGTT
CGAACGGGTGAATTACGTGGTGCGTTATGGTCTGAAATTTATACTGATAAAGGGTTATGGGAAATTTCTGCCGAACGCAT
GAAAATGCGGCGTCCTCATATTGTTCCGTTATCCGTGCAGGCATTGGAAATTATTGAAAAAATCAGGGCAATGACTGGTA
ATTTTCATCTAATGTTCCCCGGTCGTAATGATCCAAGTAAAACAATGAGCGAAGCCAGTATCAATCAGGTGTTTAAGCGA
ATTGGCTATACCGGCCGCGTTACGGGGCATGGATTCCGTCATACCATGAGCACCGTTCTTCATGAACAAGGCTACAACAC
CGCATGGATTGAAACCCAGCTTGCGCATCTTGATAAGAATGCTATCCGTGGTACCTATAACCATGCGCAATATCTTGATG
GCAGACGTGAGATGCTGCAATGGTATGCTGACTATATGGATAGCCTTGAGAATGGTGGCAATGTGATGCATGGGACGTTT
AATCGACGTGCATAG

Protein sequence :
MKLNARQVETAKPKDKPYKLADGGGMYLEVFPNGTKSWRMKYRIAGKEKRVVFGVYPTITLADARSKRDDAKKLLVNGVD
PSAFKKESKLAQIEEVKNTFQQIALEWHNMKVKKWSAGYASDILEAFNKDVFPFIGQRPVADIKPLELLNVLKKMEERGA
TEKAKKVRQRCGEVFRYAIVTGRAEYNPAPDLTSAMQGHESKHYPFLTIEELPAFFKALAGYSGSELVVLAARLMIITGV
RTGELRGALWSEIYTDKGLWEISAERMKMRRPHIVPLSVQALEIIEKIRAMTGNFHLMFPGRNDPSKTMSEASINQVFKR
IGYTGRVTGHGFRHTMSTVLHEQGYNTAWIETQLAHLDKNAIRGTYNHAQYLDGRREMLQWYADYMDSLENGGNVMHGTF
NRRA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ESA_03025 YP_001439090.1 hypothetical protein Not tested Not named Protein 8e-143 71
aec33 AAW51716.1 Int Not tested AGI-3 Protein 6e-124 63
int CAC39282.1 integrase Not tested LPA Protein 3e-124 63
int AAD54663.1 Sai integrase Not tested SHI-2 Protein 1e-123 63
S4835 NP_839238.1 integrase Not tested SHI-2 Protein 2e-123 63
SF3698 NP_709437.1 integrase Not tested SHI-2 Protein 2e-123 63
int AAC31482.1 CP4-like integrase Not tested LEE Protein 3e-123 62
int ACU09430.1 integrase Not tested LEE Protein 3e-123 62
intL NP_290239.1 integrase for prophage 933L and the LEE pathogenicity island Not tested LEE Protein 4e-123 62
ECs4534 NP_312561.1 integrase Not tested LEE Protein 4e-123 62
int AAD44730.1 Int Not tested SHI-2 Protein 2e-123 62
unnamed AFX83955.1 integrase Not tested SE-PAI Protein 6e-120 58
STY4821 NP_458899.1 integrase Not tested SPI-10 Protein 1e-75 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
KPK_4426 YP_002240225.1 phage integrase family site-specific recombinase VFG0598 Protein 7e-124 63
KPK_4426 YP_002240225.1 phage integrase family site-specific recombinase VFG0783 Protein 2e-123 62