Gene Information

Name : ribD (KPK_4318)
Accession : YP_002240118.1
Strain : Klebsiella pneumoniae 342
Genome accession: NC_011283
Putative virulence/resistance : Unknown
Product : bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0117
EC number : -
Position : 4354392 - 4355495 bp
Length : 1104 bp
Strand : -
Note : riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine a

DNA sequence :
ATGCAGGACGAAATGTACATGGCGCGAGCGCTGAAGCTTGCCACGCGCGGACGCTTTACCACCCATCCTAACCCTAATGT
CGGCTGCGTCATTGTGAAAGACGGCGAAATCGTCGGCGAGGGCTTTCACTATCGCGCCGGCGAGCCGCATGCTGAAGTGC
ACGCGCTCCGCATGGCCGGCGAAAAGGCGCAGGGCGCCACCGCCTACGTCACCCTTGAGCCCTGCAGCCACCATGGCCGT
ACGCCGCCGTGCTGCGATGCGCTGATCGCCGCCGGCGTTAGCCGCGTGGTCGCTGCGATGCAAGACCCAAACCCGCAGGT
GGCGGGGCGGGGTCTGTATCGTCTGCAGCAGGCCGGTATTGACGTCAGCCACGGGCTGATGATGAACGAAGCGGAAGCGC
TGAATAAAGGCTTCCTGAAGCGGATGCGCACCGGTTTTCCCTGGGTGCAGCTGAAGCTGGGCGCCTCGCTGGACGGCCGC
ACGGCGATGGCCAGCGGTGAAAGCCAGTGGATCACCTCCCCGCAGGCGCGACGCGACGTGCAGCGTCTGCGCGCCCAAAG
TCATGCCATCCTCACCAGCAGCGCCACCGTGCTGGCGGACGATCCTGCGCTGACCGTGCGCTGGCAGGAGCTGAGCGCGG
ATACTCAGGCGCTGTATCCCGAAGAGAATTTGCGCCAACCGCTGCGCGTCGTCATCGACAGTCAGAACCGCGTCACGCCT
GAGCACCGCATTGTGCAGCAGGCAGGAGAAACGCTGTTTGCCCGCCTGCGTGCGGATGAGCGCCAGTGGCCGGAAAGCGT
TCGTACGCTGCTGGTGCCGGAATATAACGGCCATCTCGATCTGGTGTTGCTGATGATGCTGCTTGGCAAACAGCAGGTGA
ACAGCGTCTGGGTGGAGGCGGGAGCGACGCTCGCCGGGGCGCTGCTGCAGGCTGGCCTTGTCGACGAGCTTATCGTCTAT
ATTGCGCCTAAACTGTTAGGCAATGCGGCGCGTGGATTATGCGCGCTGCCGGGGCTTGAAGAACTGAGCCAGGCCCCCCA
TTTCAAATTCAATGAGATACGTCAGGTTGGCCCGGATGTCTGCCTGCATTTAACCACTGCGTGA

Protein sequence :
MQDEMYMARALKLATRGRFTTHPNPNVGCVIVKDGEIVGEGFHYRAGEPHAEVHALRMAGEKAQGATAYVTLEPCSHHGR
TPPCCDALIAAGVSRVVAAMQDPNPQVAGRGLYRLQQAGIDVSHGLMMNEAEALNKGFLKRMRTGFPWVQLKLGASLDGR
TAMASGESQWITSPQARRDVQRLRAQSHAILTSSATVLADDPALTVRWQELSADTQALYPEENLRQPLRVVIDSQNRVTP
EHRIVQQAGETLFARLRADERQWPESVRTLLVPEYNGHLDLVLLMMLLGKQQVNSVWVEAGATLAGALLQAGLVDELIVY
IAPKLLGNAARGLCALPGLEELSQAPHFKFNEIRQVGPDVCLHLTTA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00289 YP_008207754.1 Pyrimidine deaminase Not tested AbaR25 Protein 1e-56 47
BJAB0868_00293 YP_008211619.1 Pyrimidine deaminase Not tested AbaR26 Protein 1e-56 47