Gene Information

Name : KPK_4092 (KPK_4092)
Accession : YP_002239895.1
Strain : Klebsiella pneumoniae 342
Genome accession: NC_011283
Putative virulence/resistance : Virulence
Product : lysine decarboxylase, constitutive
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG1982
EC number : -
Position : 4150483 - 4152630 bp
Length : 2148 bp
Strand : -
Note : identified by similarity to SP:P52095; match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711

DNA sequence :
ATGAACGTTATTGCAATCATGAATCACATGGGTGTTTACTTCAAAGAAGAACCCATCCGTGAACTGCATCGTGCTCTCGA
ACGCCTGGACTTCCGTATTGTCTACCCGAACGACCGTGACGACTTATTAAAACTTATCGAAAACAACTCTCGTCTGTGCG
GCGTGATCTTCGACTGGGATAAATACAATCTCGAACTGTGCGAAGAAATCAGCAAAATGAACGAGTACATGCCGCTGTAC
GCGTTCGCTAACACCTACTCGACTCTGGACGTTAGCCTGAACGATCTGCGCATGCAGGTTCGCTTCTTCGAATATGCGCT
GGGCGCTGCGGAAGATATCGCGAACAAAATCAAACAGAACACTGACGAATACATCGACACCATTCTGCCGCCGCTGACCA
AAGCGCTGTTCAAATATGTACGTGAAGGCAAATACACCTTCTGTACCCCTGGCCACATGGGCGGTACCGCGTTCCAGAAA
AGCCCGGTAGGCAGCATCTTCTATGATTTCTTTGGTTCCAACACCATGAAATCCGATATCTCCATTTCGGTTTCTGAACT
GGGTTCCCTGCTGGACCACAGCGGCCCGCACAAAGAAGCGGAAGAGTATATCGCTCGTGTGTTTAACGCAGAACGCAGCT
ACATGGTGACCAACGGTACCTCTACTGCTAACAAAATCGTCGGCATGTACTCCGCGCCGGCCGGCAGCACCGTGCTGATT
GACCGTAACTGCCACAAATCGCTGACTCACCTGATGATGATGAGCGACATTACGCCGATCTACTTCCGTCCGACCCGTAA
CGCCTACGGTATCCTCGGCGGTATCCCGCAGAGCGAATTCCAGCACGCGACTATCGCCAAGCGTGTGAAAGAGACGCCGA
ATGCGACCTGGCCGGTACACGCGGTGATCACCAACTCAACCTATGATGGTCTGCTGTATAACACCGACTTCATCAAGAAA
ACCCTGGATGTGAAATCCATCCACTTTGACTCCGCATGGGTCCCTTACACCAACTTCTCGCCGATCTATGAAGGCAAATG
CGGGATGAGCGGCGGTCGCGTTGAAGGGAAAGTGATCTACGAAACCCAGTCCACGCATAAACTGCTGGCGGCGTTCTCTC
AGGCTTCGATGATCCACGTGAAAGGCGACGTTAACGAAGAAACCTTCAACGAAGCCTACATGATGCACACCACCACTTCC
CCGCACTACGGGATCGTGGCGTCCACCGAAACCGCGGCGGCGATGATGAAGGGTAACGCCGGTAAGCGTCTGATCGACGG
CTCTATTGAACGTTCCATCAAGTTCCGTAAAGAGATCAAACGTCTGAAAGGCGAGTCTGAAGGCTGGTTCTTCGATGTAT
GGCAGCCGGAACATATCGATGGCGCTGAATGCTGGCCGCTGCGCTCCGATAGCGCATGGCACGGTTTCAAAAACATCGAT
AACGAGCACATGTACCTCGACCCGATCAAAGTCACGCTGCTGACGCCGGGGATGAAGAAAGACGGCACCATGGATGAGTT
CGGTATTCCGGCAAGCATCGTGGCGAAATATCTCGACGAACACGGCATCGTGGTTGAGAAAACCGGTCCGTACAACCTGC
TGTTCCTGTTCAGCATCGGTATCGATAAGACAAAAGCGCTGAGCCTGCTGCGTGCGCTGACCGACTTCAAACGCGCGTTC
GACCTGAACCTGCGGGTGAAAAACATGCTGCCGTCTCTGTACCGTGAAGATCCTGAATTCTATGAAAACATGCGTATTCA
GGACCTGGCGCAGAACATTCACAAACTGATTGAGCATCACAACCTGCCGGACCTGATGTTCCGCGCGTTTGAAGTGCTGC
CATCGATGGTGATGACCCCGTATGCCGCGTTCCAGAAAGAGCTGCACGGTCAGACTGAAGAGGTTTATCTCGAAGAGATG
GTCGGCCGCGTCAACGCCAACATGATTCTGCCGTATCCTCCGGGAGTGCCGCTGGTGATGCCGGGTGAAATGATCACCGA
AGAAAGCCGCCCGGTGCTGGAGTTCCTGCAGATGCTGTGTGAAATCGGCGCCCACTACCCGGGCTTCGAAACCGATATCC
ACGGCGCCTATCGTCAGGCGGATGGTCGTTACACCGTTAAAGTGCTGAAAGAAGAAAACAACAAGTAA

Protein sequence :
MNVIAIMNHMGVYFKEEPIRELHRALERLDFRIVYPNDRDDLLKLIENNSRLCGVIFDWDKYNLELCEEISKMNEYMPLY
AFANTYSTLDVSLNDLRMQVRFFEYALGAAEDIANKIKQNTDEYIDTILPPLTKALFKYVREGKYTFCTPGHMGGTAFQK
SPVGSIFYDFFGSNTMKSDISISVSELGSLLDHSGPHKEAEEYIARVFNAERSYMVTNGTSTANKIVGMYSAPAGSTVLI
DRNCHKSLTHLMMMSDITPIYFRPTRNAYGILGGIPQSEFQHATIAKRVKETPNATWPVHAVITNSTYDGLLYNTDFIKK
TLDVKSIHFDSAWVPYTNFSPIYEGKCGMSGGRVEGKVIYETQSTHKLLAAFSQASMIHVKGDVNEETFNEAYMMHTTTS
PHYGIVASTETAAAMMKGNAGKRLIDGSIERSIKFRKEIKRLKGESEGWFFDVWQPEHIDGAECWPLRSDSAWHGFKNID
NEHMYLDPIKVTLLTPGMKKDGTMDEFGIPASIVAKYLDEHGIVVEKTGPYNLLFLFSIGIDKTKALSLLRALTDFKRAF
DLNLRVKNMLPSLYREDPEFYENMRIQDLAQNIHKLIEHHNLPDLMFRAFEVLPSMVMTPYAAFQKELHGQTEEVYLEEM
VGRVNANMILPYPPGVPLVMPGEMITEESRPVLEFLQMLCEIGAHYPGFETDIHGAYRQADGRYTVKVLKEENNK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cadA NP_756988.1 lysine decarboxylase, inducible Not tested PAI II CFT073 Protein 0.0 95
unnamed CAD66195.1 putative cadaverin decarboxylase Virulence PAI III 536 Protein 0.0 67

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
KPK_4092 YP_002239895.1 lysine decarboxylase, constitutive VFG1670 Protein 0.0 67