Gene Information

Name : KPK_4090 (KPK_4090)
Accession : YP_002239893.1
Strain : Klebsiella pneumoniae 342
Genome accession: NC_011283
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : -
Position : 4147098 - 4148615 bp
Length : 1518 bp
Strand : -
Note : class II; inducible; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; induced by high temperature, anaerobiosis, and l

DNA sequence :
ATGTCTGAACAACAAGCACAAGGTGCCGATGAGGCCATTGACCTTAATAATGAACTGAAAACTCGTCGCGAAAAACTGGC
TGCACTGCGTGAGCAGGGCGTAGCCTTCCCCAACGACTTCCGTCGCGATCATACCTCTGACCAATTGCATGCTGAATTCG
ATGCGAAGGATAACGATGAACTCGCTTCCCTGAACGTTGAAGTTGCGGTGGCTGGCCGGATGATGACCCGCCGCGTGATG
GGCAAAGCCTCTTTCGTCACTCTTCAGGACGTCGGCGGCCGCATTCAGCTGTACGTGGCGCGCGATGACCTGCCGGAAGG
CGTCTACAACGAACAGTTTAAAAAATGGGACCTCGGCGATATCATCGCCGCCCGCGGCAAGCTGTTCAAAACGCAAACCG
GCGAACTCTCTATTCACTGCACCGAGCTGCGTCTGCTGACCAAAGCCCTGCGCCCGCTGCCGGATAAATTCCACGGCCTG
CAGGATCAGGAAGTCCGCTATCGCCAGCGCTATCTGGATCTGATCGCCAACGAAGAGTCACGTCATACGTTCCGTATCCG
TTCGCAGATCCTCGCGACCATGCGCCAGTTCATGGTGGCTCGTGGCTTTATGGAAGTCGAAACCCCGATGATGCAGGTGA
TCCCTGGCGGGGCGTCCGCCCGTCCGTTCATCACCCATCACAACGCGCTGGATCTGGATATGTACCTGCGCATCGCGCCG
GAACTGTATCTGAAACGTCTGGTGGTCGGCGGTTTTGAACGCGTGTTTGAAATCAACCGCAACTTCCGTAATGAAGGGAT
CTCGGTACGCCATAACCCAGAGTTCACCATGATGGAACTGTATATGGCGTATGCGGACTACAAAGACCTGATCGAACTGA
CCGAGTCGTTGTTCCGCACCCTGGCGCAGACGGTGCTGGGCAAAACCGAAGTGCCATATGGCGACCAGGTGTTTGATTTC
GGCAAGCCGTTTGAAAAACTGACCATGCGCGAAGCGATCAAGAAACACCGTCCGGAAACCAACATGGCGGATCTGGATAA
CTTCGACGCGGCGAAAGCGCTGGCGGAATCTCTCGGTATTCAGGTAGAGAAAAGCTGGGGTCTGGGACGTATCGTCACCG
AAATCTTTGACGAAGTGGCGGAAGCGCATCTGATTCAGCCAACCTTCATCACCGAATACCCGGCGGAAGTTTCCCCGCTG
GCTCGCCGTAACGACGTCAACCCGGAAATCACTGACCGCTTTGAATTCTTCATCGGCGGCCGCGAAATCGGTAACGGTTT
CAGCGAGCTGAACGATGCCGAAGATCAGGCGCAGCGCTTCCAGGATCAGGTGAACGCCAAAGCGGCGGGCGATGACGAAG
CGATGTTCTATGACGAAGACTATGTTACCGCCCTGGAGTATGGTTTACCGCCGACCGCGGGTCTGGGTATCGGTATCGAC
CGCATGGTGATGCTGTTTACCAACAGCCATACCATCCGCGACGTGATCCTCTTCCCGGCCATGCGTCCGCAGAAGTAA

Protein sequence :
MSEQQAQGADEAIDLNNELKTRREKLAALREQGVAFPNDFRRDHTSDQLHAEFDAKDNDELASLNVEVAVAGRMMTRRVM
GKASFVTLQDVGGRIQLYVARDDLPEGVYNEQFKKWDLGDIIAARGKLFKTQTGELSIHCTELRLLTKALRPLPDKFHGL
QDQEVRYRQRYLDLIANEESRHTFRIRSQILATMRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYLRIAP
ELYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYKDLIELTESLFRTLAQTVLGKTEVPYGDQVFDF
GKPFEKLTMREAIKKHRPETNMADLDNFDAAKALAESLGIQVEKSWGLGRIVTEIFDEVAEAHLIQPTFITEYPAEVSPL
ARRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAQRFQDQVNAKAAGDDEAMFYDEDYVTALEYGLPPTAGLGIGID
RMVMLFTNSHTIRDVILFPAMRPQK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 5e-171 68

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
KPK_4090 YP_002239893.1 lysyl-tRNA synthetase VFG1668 Protein 3e-171 68