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Name : leuS (KPK_3899) Accession : YP_002239703.1 Strain : Klebsiella pneumoniae 342 Genome accession: NC_011283 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : - Position : 3943488 - 3946070 bp Length : 2583 bp Strand : + Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGCAAGAGCAATACCGCCCGGAAGAGATAGAATCGAAAGTCCAGCTTCACTGGGACGAAAATCGTACATTTGAAGTAAC TGAAGACGAGAGCAAAGAGAAGTATTACTGCCTGTCGATGCTTCCTTATCCTTCTGGTCGACTACACATGGGTCACGTGC GTAACTACACCATCGGCGACGTGATTGCCCGCTACCAGCGTATGCTGGGCAAAAACGTCCTGCAGCCGATTGGCTGGGAT GCGTTTGGTCTGCCGGCGGAAGGCGCGGCAGTGAAAAACAACACCGCGCCAGCACCGTGGACCTACGACAACATCGCCTA CATGAAAAACCAGCTCAAAATGCTGGGTTTTGGCTATGACTGGAGCCGCGAGCTGGCGACCTGCACCCCGGAATACTACC GCTGGGAGCAGAAGTTCTTCACCGAGCTGTACAAAAAAGGGCTGGTATACAAGAAAACCTCCGCGGTGAACTGGTGCCCG AACGACCAGACCGTACTGGCCAACGAACAGGTTATCGACGGCTGCTGCTGGCGCTGCGATACCAAAGTCGAGCGTAAAGA GATCCCGCAGTGGTTTATTAAAATCACCGCCTACGCCGATGAACTGCTGAACGATCTGGATAAACTGGATCACTGGCCAG ACACCGTAAAGACCATGCAGCGCAACTGGATCGGCCGTTCCGAAGGGGTGGAAATCTCCTTTGACGTCAACAACTACGCC GATAAGCTGACCGTCTACACCACCCGTCCGGACACCTTTATGGGCTGCACCTACCTGGCTGTCGCGGCGGGTCACCCGCT GGCGCAGCAGGCTGCAGCGAACAATCCGGCGCTGGCTGCCTTTATCGACGAATGCCGTAATACCAAAGTAGCCGAAGCCG ACATGGCGACGATGGAGAAAAAAGGCGTCGATACCGGGTTTAAAGCCATTCACCCGCTGACCGGCGAAGAAATTCCTGTC TGGGCGGCAAACTTCGTGCTGATGGAATATGGCACCGGCGCGGTCATGGCCGTTCCGGGTCACGACCAGCGTGACTATGA GTTCGCCAGCAAGTACGGTCTGAACATCAAGCCGGTTATCCTCGCCGCTGACGGCAGCGAGCCGGATCTCTCCGCGCAGG CGCTGACCGAGAAAGGCGTCCTGTTTAACTCCGGCGAGTTCAGCGGCCTCGATTATGAAGCCGGCTTCAACGCCATTGCC GACAAACTGGCAGCCATGGGCGTAGGCGAGCGTAAAATTAACTACCGTCTGCGTGACTGGGGTGTGTCCCGTCAACGCTA CTGGGGTGCGCCGATCCCGATGGTGACCCTGGAAGATGGCACCGTGCTGCCGACCCCGGAAGATCAACTGCCGGTGATCC TGCCGGAAGATGTGGTCATGGACGGCATCACCAGCCCGATCAAAGCCGATCCTGAATGGGCGAAGACCACCGTTAACGGT CAGCCGGCGCTGCGTGAAACCGACACCTTTGACACCTTTATGGAATCCTCCTGGTACTATGCGCGCTACACCTGCCCGCA GTATCAGGAAGGGATGCTGGATTCGAAAGCGGCCAACTACTGGCTGCCGGTAGATATCTACATCGGCGGTATCGAACACG CCATCATGCACCTGCTCTACTTCCGCTTCTTCCACAAGCTGATGCGCGACGCGGGCATGGTCAACTCCGATGAGCCGGCG AAGCAGCTGCTGTGCCAGGGCATGGTGCTGGCTGACGCCTTCTACTATGTAGGCGAAAACGGCGAACGTAACTGGGTTTC CCCGGTTGACGCCATCGTTGAGCGCGACGAAAAAGGCCGCATCGTGAAAGCGAAAGACGCGGCAGGCCATGAGCTGGTGT ACACCGGCATGAGCAAGATGTCCAAGTCGAAAAACAACGGCATCGACCCGCAGGTGATGGTTGAGCGTTATGGCGCGGAT ACCGTGCGTCTGTTCATGATGTTTGCGTCCCCGGCGGATATGACCCTCGAGTGGCAGGAATCTGGCGTTGAAGGGGCTAA CCGCTTCCTGAAACGCGTCTGGAAACTGGTCTACGAGCACACCACCAAAGGGGACGTTGCGGCACTGAACGTGGCGGCGC TGAGTGAAGATCAGAAAGCGCTGCGTCGCGATATTCACAAAACGATCGCCAAAGTGACTGATGACATCGGCCGTCGTCAG ACCTTCAACACCGCCATCGCGGCGATCATGGAGCTGATGAACAAGCTGGCGAAAGCGCCGCAGGAAGACGAACAGGATCG TGCCCTGATGCAGGAAGCGCTGCTGGCGGTGGTGCGTATGCTGAACCCGTTCACCCCGCACGCCAGCTTCACACTGTGGC GCGAGCTGAACGGCGAAGGCGATATCGACAACGCGCCGTGGCCGGTGGCGGATGAAAGCGCGATGGTGGAAGACAGCACC CTCGTCGTCGTCCAGGTCAATGGCAAAGTTCGTGGTAAAATTACCGTTGCGGTAGATGCAACTGAAGAGCAGGTCCGCGA GCGTGCCGGCCAGGAGCATCTGGTCGCGAAATATCTCGACGGTAAAACCGTGCGTAAAGTGATTTACGTTCCGGGTAAAC TGCTCAATCTGGTCGTTGGCTAA Protein sequence : MQEQYRPEEIESKVQLHWDENRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVIARYQRMLGKNVLQPIGWD AFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSRELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCP NDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEISFDVNNYA DKLTVYTTRPDTFMGCTYLAVAAGHPLAQQAAANNPALAAFIDECRNTKVAEADMATMEKKGVDTGFKAIHPLTGEEIPV WAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPVILAADGSEPDLSAQALTEKGVLFNSGEFSGLDYEAGFNAIA DKLAAMGVGERKINYRLRDWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILPEDVVMDGITSPIKADPEWAKTTVNG QPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVNSDEPA KQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGAD TVRLFMMFASPADMTLEWQESGVEGANRFLKRVWKLVYEHTTKGDVAALNVAALSEDQKALRRDIHKTIAKVTDDIGRRQ TFNTAIAAIMELMNKLAKAPQEDEQDRALMQEALLAVVRMLNPFTPHASFTLWRELNGEGDIDNAPWPVADESAMVEDST LVVVQVNGKVRGKITVAVDATEEQVRERAGQEHLVAKYLDGKTVRKVIYVPGKLLNLVVG |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 1e-148 | 42 |
