Gene Information

Name : KPK_3672 (KPK_3672)
Accession : YP_002239491.1
Strain : Klebsiella pneumoniae 342
Genome accession: NC_011283
Putative virulence/resistance : Virulence
Product : DNA-binding response regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 3714504 - 3715220 bp
Length : 717 bp
Strand : -
Note : identified by match to protein family HMM PF00072; match to protein family HMM PF00486

DNA sequence :
ATGGCCAAAACCATTCTGCTGGTGGAAGATGACGAGGATATTGCCACGCTGCTGCGGCTCAATCTTCAGGATGAGGGCTA
TCAGATTGTGCATGAAGCAGACGGCGACCAGGCCCTTGTCCAGCTGGAAAAGCAGGTCTGGGATGCGGTGATCCTTGATT
TGATGCTGCCTGGCGTCGATGGCCTGGAGATCTGCCGGCGTATCCGTCAGATGACCCGTTACCTGCCAGTAATTATCATC
AGCGCTCGCACCAGCGAAATGCACCGCGTGCTGGGCCTGGAGATGGGCGCCGATGATTATCTGGCGAAGCCCTTTTCACT
GCTGGAGCTTATCGCCCGCGTCAAAGCGCTGTTTCGTCGCCAGGAGGCGATGGGGCAGAACCTGCTGATGGACGCCGGGC
GCCTGTCCTGCCATGGCCTGAGCATCGATCCGCTGTCGCGCGAAGTGAAGCTGCGCGGCGAGGTGGTGGACCTGACGCCG
CGCGAATTCGATCTGCTCTATTACTTCGCCCGCCATCCCGGTGAGGTGTTTTCGCGGCTGGCGCTGCTGGAGCAGGTCTG
GGGATATCAGCACGAGGGCTATGAGCACACGGTTAATACCCATATCAACCGCCTGCGCAGCAAAATCGAACGTGACCCGG
CGGAGCCGGACATTATTCTTACCGTCTGGGGTAAAGGCTATAAATTCGCCCCGATGTCGCAAGAGGTCGCCCCGTGA

Protein sequence :
MAKTILLVEDDEDIATLLRLNLQDEGYQIVHEADGDQALVQLEKQVWDAVILDLMLPGVDGLEICRRIRQMTRYLPVIII
SARTSEMHRVLGLEMGADDYLAKPFSLLELIARVKALFRRQEAMGQNLLMDAGRLSCHGLSIDPLSREVKLRGEVVDLTP
REFDLLYYFARHPGEVFSRLALLEQVWGYQHEGYEHTVNTHINRLRSKIERDPAEPDIILTVWGKGYKFAPMSQEVAP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD42044.1 hypothetical protein Not tested PAI II 536 Protein 5e-86 79
c3565 NP_755440.1 response regulator Not tested PAI I CFT073 Protein 6e-86 79

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
KPK_3672 YP_002239491.1 DNA-binding response regulator NC_012469.1.7685629. Protein 2e-43 47
KPK_3672 YP_002239491.1 DNA-binding response regulator AE000516.2.gene3505. Protein 2e-39 45
KPK_3672 YP_002239491.1 DNA-binding response regulator NC_012469.1.7686381. Protein 2e-41 42
KPK_3672 YP_002239491.1 DNA-binding response regulator FJ349556.1.orf0.gene Protein 2e-38 42
KPK_3672 YP_002239491.1 DNA-binding response regulator HE999704.1.gene1528. Protein 9e-34 42
KPK_3672 YP_002239491.1 DNA-binding response regulator AE016830.1.gene1681. Protein 6e-43 42
KPK_3672 YP_002239491.1 DNA-binding response regulator NC_003923.1003417.p0 Protein 5e-35 41
KPK_3672 YP_002239491.1 DNA-binding response regulator NC_013450.8614146.p0 Protein 5e-35 41
KPK_3672 YP_002239491.1 DNA-binding response regulator NC_002951.3238224.p0 Protein 5e-35 41
KPK_3672 YP_002239491.1 DNA-binding response regulator AE015929.1.gene1106. Protein 1e-29 41
KPK_3672 YP_002239491.1 DNA-binding response regulator NC_007793.3914065.p0 Protein 5e-35 41
KPK_3672 YP_002239491.1 DNA-binding response regulator NC_002758.1121390.p0 Protein 5e-35 41
KPK_3672 YP_002239491.1 DNA-binding response regulator NC_010079.5776364.p0 Protein 5e-35 41
KPK_3672 YP_002239491.1 DNA-binding response regulator NC_002952.2859858.p0 Protein 5e-35 41
KPK_3672 YP_002239491.1 DNA-binding response regulator NC_007622.3794948.p0 Protein 5e-35 41
KPK_3672 YP_002239491.1 DNA-binding response regulator AF155139.2.orf0.gene Protein 3e-42 41
KPK_3672 YP_002239491.1 DNA-binding response regulator NC_002952.2859905.p0 Protein 4e-43 41
KPK_3672 YP_002239491.1 DNA-binding response regulator HE999704.1.gene2815. Protein 8e-41 41
KPK_3672 YP_002239491.1 DNA-binding response regulator CP001138.1.gene4273. Protein 2e-29 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
KPK_3672 YP_002239491.1 DNA-binding response regulator VFG1563 Protein 3e-86 79
KPK_3672 YP_002239491.1 DNA-binding response regulator VFG1702 Protein 2e-86 79
KPK_3672 YP_002239491.1 DNA-binding response regulator VFG1389 Protein 1e-30 41