Gene Information

Name : serS (KPK_3635)
Accession : YP_002239454.1
Strain : Klebsiella pneumoniae 342
Genome accession: NC_011283
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : -
Position : 3671533 - 3672825 bp
Length : 1293 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTCGATCCCAATCTGCTGCGTACCGAGCCAGACGCAGTCGCAGAAAAACTGGCACGCCGGGGCTTTAAGCTGGATGT
AGATAAACTTCGCGCGCTTGAAGAGCGTCGTAAAGTTCTGCAGGTGCAAACGGAAAACCTGCAGGCGGAGCGTAACTCCC
GATCGAAATCCATTGGCCAGGCGAAAGCGCGCGGGGAAGACATCGAGCCATTACGCCTGGAAGTGAACAAACTCGGCGAA
CAGTTGGATGCTGCAAAGTCCGAGCTGGAAACGCTGCTGGCGGAAATTCGCGATATCGCGCTGGCGATCCCGAATATTCC
TCATGATGATGTGCCGGTTGGCCGTGACGAAAACGACAACGTTGAAGTCAGCCGCTGGGGCACGCCGCGCCAGTTCGATT
TTGAAGTGCGCGATCACGTGACGCTGGGGGAAATGCACGGGGGGCTGGATTTTGCCGCCGCCGTTAAGCTGACTGGTTCG
CGTTTTGTGGTGATGAAAGGCCAGCTGGCCCGTCTGCACCGCGCCCTGGCGCAGTTCATGCTGGATCTGCACACCGAACA
GCATGGCTATAGCGAAAACTATGTCCCGTACCTGGTGAACCAGGACACGCTGTATGGCACCGGCCAGTTGCCGAAATTCG
CTGGCGACCTGTTCCATACTCGTCCGCTGGAAGAAGAAGCCGACAGCAGCAACTACGCGCTGATCCCGACGGCAGAAGTG
CCGCTGACCAACCTGGTACGCGATGAAATCATCGACGAAGACGACCTGCCGATCAAAATGACCGCCCATACGCCGTGCTT
CCGCTCTGAAGCCGGTTCCTATGGTCGCGACACCCGCGGTCTGATCCGCATGCACCAGTTCGACAAAGTTGAAATGGTGC
AGATCGTGCGTCCGGAAGACTCCATGGTCGCGCTGGAAGAGATGACCGGTCACGCCGAGAAAGTGCTGCAGCTGCTGGGT
CTGCCGTACCGTAAGGTCGCGCTGTGCACCGGCGATATGGGCTTCAGCGCCTGCAAAACCTACGACCTGGAAGTGTGGGT
TCCGGCGCAGAACACCTACCGTGAAATCTCTTCCTGCTCTAACGTCTGGGATTTCCAGGCGCGTCGTATGCAGGCCCGCT
GCCGCAGCAAGTCCGACAAGAAGACTCGCCTCGTTCATACTCTGAATGGTTCTGGTCTGGCGGTAGGTCGTACCCTGGTG
GCGCTGATGGAAAACTATCAGCAGGCCGATGGCCGTATTGAGATCCCGGAAATTCTGCGCCCGTATATGCGTGGCCTCGA
ATATATCGGGTAA

Protein sequence :
MLDPNLLRTEPDAVAEKLARRGFKLDVDKLRALEERRKVLQVQTENLQAERNSRSKSIGQAKARGEDIEPLRLEVNKLGE
QLDAAKSELETLLAEIRDIALAIPNIPHDDVPVGRDENDNVEVSRWGTPRQFDFEVRDHVTLGEMHGGLDFAAAVKLTGS
RFVVMKGQLARLHRALAQFMLDLHTEQHGYSENYVPYLVNQDTLYGTGQLPKFAGDLFHTRPLEEEADSSNYALIPTAEV
PLTNLVRDEIIDEDDLPIKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVEMVQIVRPEDSMVALEEMTGHAEKVLQLLG
LPYRKVALCTGDMGFSACKTYDLEVWVPAQNTYREISSCSNVWDFQARRMQARCRSKSDKKTRLVHTLNGSGLAVGRTLV
ALMENYQQADGRIEIPEILRPYMRGLEYIG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 7e-107 57