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Name : topB (KPK_3236) Accession : YP_002239062.1 Strain : Klebsiella pneumoniae 342 Genome accession: NC_011283 Putative virulence/resistance : Unknown Product : DNA topoisomerase III Function : - COG functional category : L : Replication, recombination and repair COG ID : COG0550 EC number : - Position : 3288665 - 3290611 bp Length : 1947 bp Strand : - Note : decatenates replicating daughter chromosomes DNA sequence : ATGCGGTTGTTTATTGCGGAAAAACCGAGTCTTGGTCGGGCTATCGCCGATGTGTTGCCTAAACCGCACCGCAAAGGCGA TGGCTATATTGAGTGCGGCAACGGGCAGGTGGTCACCTGGTGTATCGGCCATCTGCTGGAGCAGGCGCAGCCGGACGTCT ATGACAGCCGCTATGCCCGCTGGAATCTCACCGACCTGCCGATTGTGCCGGAGAAATGGCAGCTACAACCCAAACCCTCG GTCACCAAACAGCTCAATGTGATCAAGCGTCTGCTTGGCGAGGCGCAGGAAGTGATCCATGCCGGCGACCCCGACCGTGA GGGGCAGCTGCTGGTGGACGAAGTACTCGATTACCTGCAGCTGGCGCCGGAGAAGCGTCAGCAGGTGCAGCGCTGTCTGA TTAACGATCTCAACCCGCAGGCGGTGGAGCGGGCGATCAATCGCCTGCGCGCCAACAGCGAGTTCGTGCCGCTCTGCGTG TCGGCGCTGGCGCGGGCGCGTGCCGACTGGCTGTACGGCATCAATATGACCCGCGCCTATACTCTGCTGGGGCGCAACGC CGGCTATCAGGGGGTACTGTCCGTGGGGCGGGTGCAGACCCCGGTACTTGGCCTGGTGGTTCGCCGTGATGAAGAGATTG AAAACTTCGTCGCCAAAGACTTCTTCGACGTGAAGGCGCATATCGTCACGCCGCAGGAGGAACGTTTTGTCGCCACCTGG GTGCCAAGCGAAGCCTGCGAACCTTACCAGGATGAAGAAGGGCGTCTGCTGCATCGTCCACTGGCTGAGCACGTGGTTAA GCGCATCGAAGGCCAGCCGGCGCTGGTGACCGGCTATAACGATAAGCGCGATTCCGAACCCGCGCCGCTGCCGTTCTCGC TGTCGGCGCTACAGATTGAGGCGGCCAAACGTTTCGGCTTCAGCGCGCAAAACGTGCTGGATATCTGCCAGAAGCTGTAC GAAACCCACAAGCTCATTACCTACCCGCGTTCGGATAGCCGCTACCTGCCGGAAGAGCACTTCGCCGGCCGTCATGCGGT GCTGAATGCGATTGCCGTCCATGCGGCGGACCTGCTGCCGCAGCCGGTGATGGATCCGGAGATCCGCAACCGCTGCTGGG ATGATAAAAAGGTCGATGCGCACCATGCGATTATCCCGACCGCCCGCAGCAGCCAGGTCAAGCTCACCGATAACGAAGCG AAGGTCTACCACCTGATCGCCCGGCAGTATCTGATGCAGTTCTGCCCGGACGCGGTGTTCCGCAAATGCCAGATTGACCT CGAGATCGCCAACGGCAAGTTTGTCGCCAAGGCGCGTTTTCTGGCAGAGGCTGGCTGGCGGACGCTGCTGGGCAGCAAAG AGCGCGATGAAGAGAACGACGGCACGCCGCTGCCGGTGGTGGCCAAAGACGATGAACTGCTGTGCGAGAAGGGCGAAGTG GTGGAGCGTCAGACGCAGCCGCCGCGCCACTTCACCGACGCCACGCTGCTGTCGGCGATGACCGGGATTGCCCGTTTCGT GCAGGATAAAGATCTGAAGAAGATCCTCCGCGCCACCGACGGTCTCGGCACAGAAGCGACCCGCGCCGGGATTATCGAGC TGCTGTTCAAGCGCGGTTTCCTGACCAAAAAGGGGCGTTATATCCACTCCTCGGACGCTGGCCGGGCGCTGATTCACTCC TTGCCGGAGATGGCCGCGCGTCCGGATATGACCGCCCACTGGGAATCGGTCCTGACGCAGATCAGCGAAAAGCAGTGCCG CTATCAGGACTTTATGCAGCCGCTGGTGGGGACGCTGTTCCAGCTGATCGATCAGGCACGGAGCACGCCAGTGCGCCAGT TCCGCGGCCTGGCCGCGCCGGGCGGGGCGAAAAAGTCGTTCAGCAAAGGTAAAGGCAAGCCGAAAGGGAAAAAAGCGGCA GACGATGCTGCGCCGCCGCCGCAGTAA Protein sequence : MRLFIAEKPSLGRAIADVLPKPHRKGDGYIECGNGQVVTWCIGHLLEQAQPDVYDSRYARWNLTDLPIVPEKWQLQPKPS VTKQLNVIKRLLGEAQEVIHAGDPDREGQLLVDEVLDYLQLAPEKRQQVQRCLINDLNPQAVERAINRLRANSEFVPLCV SALARARADWLYGINMTRAYTLLGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFDVKAHIVTPQEERFVATW VPSEACEPYQDEEGRLLHRPLAEHVVKRIEGQPALVTGYNDKRDSEPAPLPFSLSALQIEAAKRFGFSAQNVLDICQKLY ETHKLITYPRSDSRYLPEEHFAGRHAVLNAIAVHAADLLPQPVMDPEIRNRCWDDKKVDAHHAIIPTARSSQVKLTDNEA KVYHLIARQYLMQFCPDAVFRKCQIDLEIANGKFVAKARFLAEAGWRTLLGSKERDEENDGTPLPVVAKDDELLCEKGEV VERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATRAGIIELLFKRGFLTKKGRYIHSSDAGRALIHS LPEMAARPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLFQLIDQARSTPVRQFRGLAAPGGAKKSFSKGKGKPKGKKAA DDAAPPPQ |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| topB | NP_458624.1 | topoisomerase B | Not tested | SPI-7 | Protein | 1e-110 | 41 |
| topB | NP_807836.1 | DNA topoisomerase III | Not tested | SPI-7 | Protein | 1e-110 | 41 |
| topB | AAF14809.1 | topoisomerase B | Not tested | SPI-7 | Protein | 8e-111 | 41 |
| topB | AAN62317.1 | putative DNA topoisomerase III | Not tested | PAGI-3(SG) | Protein | 9e-107 | 41 |
| pph56 | CAI36097.1 | Topoisomerase IA | Not tested | PPHGI-1 | Protein | 1e-102 | 41 |
| topB1 | YP_005176228.1 | DNA topoisomerase III | Not tested | ICEPmu1 | Protein | 3e-110 | 41 |
