Gene Information

Name : umuC (KPK_3125)
Accession : YP_002238952.1
Strain : Klebsiella pneumoniae 342
Genome accession: NC_011283
Putative virulence/resistance : Unknown
Product : DNA polymerase V subunit UmuC
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0389
EC number : -
Position : 3185304 - 3186569 bp
Length : 1266 bp
Strand : -
Note : binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization

DNA sequence :
ATGTTTGCACTTTGCGATGTGAACTCATTTTACGCATCCTGCGAAACTGTTTTCCGTCCTGACCTGAAGGGGCGTCCGGT
GGTCGTTCTGTCAAACAACGACGGCTGTGTGATCGCCCGCTCGCAAGAGGCGAAGCCCTTCGTCAAAATGGGCGAGCCTT
ATTTCAAGCAAAAGCACATGTTTCGCCGGCACGGTATTATCGCGTTTAGCAGCAACTATGAGCTTTATGCCGATATGTCC
AACCGAGTGATGACAACGCTGGAGGAACTCTCTCCACGCTGCGAAATTTACAGTATTGATGAGGCATTTTGCGACCTGAC
AGGAGTTCGGAATTGTCGCGACCTTACCGACTTTGGCAGGGAAATTCGCGAGACGGTTCTGCGCAGGACGCACCTCACGG
TCGGTGTCGGCATAGCCCAGACTAAAACCCTGGCAAAGCTGGCCAATCACGCGGCGAAACAGTGGCAGCGACAGACCGGA
GGAGTGGTGGATCTGTCTAATCTTGAAAGGCAGAGGAAGTTGATGGCTTTGCTGCCGGTGGATGAGGTCTGGGGCGTCGG
GCGCCGTATTAGTAAAAAGCTGGAGGCCATGGGGATTAAAACGGTACTGCAACTAGCGGATACCGATATCCGTTTTATCC
GGAAGCATTTTAATGTGGTTTTGGAGCGAACTGTGCGGGAGCTGCGCGGAGAGCCATGTCTCGGTCTTGAGGAGTTCGCG
CCGGTAAAGCAGGAGATTGTCTGTAGTCGCAGCTTTGGGCAGCGGATTTCCACCTACGAAGAGATGCGCCAGGCGATATG
TCTTTACGCATCCAGAGCAGCGGAGAAACTCCGTGGTGAACATCAGTACTGCCGCTTTATCTCTGCGTTCGTCAAAACCA
GCCCCTTTGCTCTGAATGAACCCTATTACGGAAACAGCACATCGGTAAAGCTGCTAACACCTACCCAGGACAGCCGGGAC
ATCATCACCGCGGCGACGAAATGTCTCGATGCAATCTGGCGAGTCGGGCATCGCTACCAGAAAGCAGGAGTAATGCTGGG
AGATTTCTACAGCCAGGACGTAGCGCAGCTCAACCTCTTCGACGACAACGCGCCACGGAAGAACAGTGAAAAGCTCATGG
AAGTTCTCGATCATCTCAATGCGAAAGACGGACGGGGAACTCTATATTTTGCAGGGCAGGGAATCCAGAGCGCCTGGCAG
ATGAAGCGGGAAATGCTATCGCCACGTTATACAACCCGGTTTTCAGATCTACCAGTTGTCAGGTAA

Protein sequence :
MFALCDVNSFYASCETVFRPDLKGRPVVVLSNNDGCVIARSQEAKPFVKMGEPYFKQKHMFRRHGIIAFSSNYELYADMS
NRVMTTLEELSPRCEIYSIDEAFCDLTGVRNCRDLTDFGREIRETVLRRTHLTVGVGIAQTKTLAKLANHAAKQWQRQTG
GVVDLSNLERQRKLMALLPVDEVWGVGRRISKKLEAMGIKTVLQLADTDIRFIRKHFNVVLERTVRELRGEPCLGLEEFA
PVKQEIVCSRSFGQRISTYEEMRQAICLYASRAAEKLRGEHQYCRFISAFVKTSPFALNEPYYGNSTSVKLLTPTQDSRD
IITAATKCLDAIWRVGHRYQKAGVMLGDFYSQDVAQLNLFDDNAPRKNSEKLMEVLDHLNAKDGRGTLYFAGQGIQSAWQ
MKREMLSPRYTTRFSDLPVVR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
samB NP_458681.1 UV protection protein Not tested SPI-7 Protein 3e-128 64
umuC NP_807889.1 DNA polymerase V subunit UmuC Not tested SPI-7 Protein 3e-128 64
rulB CAI36137.1 nucleotidyltransferase/DNA polymerase Not tested PPHGI-1 Protein 6e-96 52
unnamed ABR13403.1 DNA-directed DNA polymerase Not tested PAGI-5 Protein 4e-75 49