Gene Information

Name : lpfC (KPK_2634)
Accession : YP_002238465.1
Strain : Klebsiella pneumoniae 342
Genome accession: NC_011283
Putative virulence/resistance : Virulence
Product : outer membrane usher protein LpfC
Function : -
COG functional category : N : Cell motility
COG ID : COG3188
EC number : -
Position : 2694628 - 2697162 bp
Length : 2535 bp
Strand : -
Note : identified by similarity to SP:P43662; match to protein family HMM PF00577

DNA sequence :
ATGATGATGGCAATGGATTATATAAAAGTACGATCTCCACGGTTGGCATTGTTGATAACCATCGCGCTCTTCGGTACTAC
ACAAAATAGCTATAGTCGCGATTTTTTTAACCCAGAGCTGGTTGAACTGGATAATCCAGGGACAGAAAGAGTCGATCTTT
CAGGTTTTGAATCTGGTGAGCAAGCCCCCGGGAATTATCATGTTGATGTCGTCCTGGACGATCAGTTAGTCGATACCCGC
GATATTATGTTTGTTTTGCTGAAAGAGCGTGGCGATGAAGAAAAATTAGTCCCCTGTTTATCCATTGAGCAATTAGCAAG
CTGGGGAGTCAAGACTGGACTTTTTCCTGCGTTAAAGGGCGAAACCTCCTGTGCGAACCTGTCCGCCATTCCTCAGGCCA
GTACAGATTTCCAGTTTGCCATGCAGCGTCTGGTATTGAGCATTCCGCAAGCGGCAATCTCAGCGCAAGCTCGTGGATCG
GTGCCACCAGATCGCTGGGATGAAGGGATTAACGCCGCCCTGCTTAACTACAGTCTGAGTGGGGCGAATAACTGGGCCAA
AAATAACAACAGCAGCAACAGTGATAGCCAGTATGCCAACCTGCGTCCGGGAGTAAACATCGGCCCCTGGCGGTTAAGAA
ATTACACCACCTGGTCGCGAGATTCACAGGGGCACGATGCCTGGGACACGGTTTATACCTATGCACAACGTACGATAATC
CCGTTAAAGTCGCAGCTCACACTGGGTGACAGTTCTGCCCCGGCAGATGTTTTCGACAGTATTCCTTTCCGGGGAGGACA
ACTTGCTTCCGATGATGACATGCTGCCCGACTCCCTTAAGGGCTATGCCCCTGTGGTGCGTGGTATCGCCCGGACCAATG
CCCAGGTGATCATCCGCCAGAATGGCTATCAGATTTACCAGAGCTTTGTGGCGCCGGGCGCGTTTGAAATTACGGACATG
TATCCTACCGGCGGCGCCGGCGATCTTGATGTCACGATTAAAGAGGCTGATGGTAGTGAGCAGCACTTTAGCGTGCCATT
TGCCTCACTTCCCGTATTACAGCGTGAAGGCCGAATAAAATATGCGTTAACGGGCGGCCAATATCGTTCGTACAACGGCA
GCGTGGATAAGACACCCTTTGGCCAGATGAGCGTTATTCTCGGCTTGCCCTACGGGTTCACGTTTTACGGTGGATTGCAG
GAGTCGAGTAAATATCAGTCGCTTGCCGCGGGCGTGGGTAAAAACATGGGTGACTTTGGCGCTATCTCCAGCGACATCAC
CCAGGGCTGGTCCACGCCGTACAATATGCCGAAATCCAACGGTCAATCCTGGCGGGCTCGATACAGTAAAAACTTTGCTT
CAACAGGCACTAACTTTGCGATTGCCGGCTACCGCTATTCGACCAGCGACTACTATGGCATGCAGGAGGTCCTTGATTCT
TATGGTGACAGTAATGCGCTCCAGGATAGACGCCGCAACCGTGCGGAGCTGACGTTGAGCCAGGGGTTGGGAGATAATCT
GGGATCGTTGATGCTGAACGCCTCGCATGAAGATTACTGGAATTCAGGTAAGGCGATGGAATCCTGGAGCGTTGGGTATA
ACAACTACTGGCACAGTATCAGTTACGGTCTGACATGGACCCTGAGCAGGAATGGTAGTACGGGATCGTACAGCGCTCAC
CAGAGCGACGGTAAAAACCAGATGCTGGCGCTAAATATCAGCATCCCGCTGGAAAAACTCTTGCCGCAGACATGGGCAAA
CTATGGCATGAATGCCAGCAAGCATAACGGTACGACACACAGCGTTGGGTTGAATGGCGTTGCGATGCCGAATAATGCGC
TTAACTGGAATATTCAACAGGGTTACGGCACTCACGACGTGGCCTATACCGGCAATATGAATGGTGATTATCGAGGCACC
TATGGCGAACTGACGGCCGGGTACAGCTATGACAAAAATACCGACCGTCTGAATTATGGGATTCAGGGAGGCGTGGTTGC
GCATGCCAATGGCGTGACGTTCTCTCAGCCACTGGGTGAAACCAACGTGCTGATTGCTGCCCCCGGGGCTGCCGGTGTAG
GAATCCAGAATATGACCGGCGCGACAACCGATTATCGCGGATACACGCTTGCCTCTAACTTAATGCCTTATCGCAAAAAT
GATGTGTCATTAATCACTGAAACATTGCCGGCTAACGTTGAGTTAGAACAAACGGTCAAAACCGTGGTCCCGACGCGTGG
CGCGATTGTCAGGGCGAACTATGTGGCAAGCGTAGGCGTTCGCATGTTGATGAGCTTGACCCAGCAAAACGGCCAGTCGG
TTCCGTTTGGTGCAATTGCCAGCATTGAAGGCGCAGAACACAGCAGCTTTATCGTTGGCGAAAGCGGTCAGGTGTATTTG
ACGGGCCTGGCTCCCCAGGTCAACCTGACCGTGAAATGGGGAAATCAATCCGCAAACACCTGCAGGGTGCATTACTCGAT
TAATATGGCGAAGCTGAATAACGATGTGATTATCGATAATGCTGTTTGCCGTTAA

Protein sequence :
MMMAMDYIKVRSPRLALLITIALFGTTQNSYSRDFFNPELVELDNPGTERVDLSGFESGEQAPGNYHVDVVLDDQLVDTR
DIMFVLLKERGDEEKLVPCLSIEQLASWGVKTGLFPALKGETSCANLSAIPQASTDFQFAMQRLVLSIPQAAISAQARGS
VPPDRWDEGINAALLNYSLSGANNWAKNNNSSNSDSQYANLRPGVNIGPWRLRNYTTWSRDSQGHDAWDTVYTYAQRTII
PLKSQLTLGDSSAPADVFDSIPFRGGQLASDDDMLPDSLKGYAPVVRGIARTNAQVIIRQNGYQIYQSFVAPGAFEITDM
YPTGGAGDLDVTIKEADGSEQHFSVPFASLPVLQREGRIKYALTGGQYRSYNGSVDKTPFGQMSVILGLPYGFTFYGGLQ
ESSKYQSLAAGVGKNMGDFGAISSDITQGWSTPYNMPKSNGQSWRARYSKNFASTGTNFAIAGYRYSTSDYYGMQEVLDS
YGDSNALQDRRRNRAELTLSQGLGDNLGSLMLNASHEDYWNSGKAMESWSVGYNNYWHSISYGLTWTLSRNGSTGSYSAH
QSDGKNQMLALNISIPLEKLLPQTWANYGMNASKHNGTTHSVGLNGVAMPNNALNWNIQQGYGTHDVAYTGNMNGDYRGT
YGELTAGYSYDKNTDRLNYGIQGGVVAHANGVTFSQPLGETNVLIAAPGAAGVGIQNMTGATTDYRGYTLASNLMPYRKN
DVSLITETLPANVELEQTVKTVVPTRGAIVRANYVASVGVRMLMSLTQQNGQSVPFGAIASIEGAEHSSFIVGESGQVYL
TGLAPQVNLTVKWGNQSANTCRVHYSINMAKLNNDVIIDNAVCR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
fim2D AFH78429.1 putative fimbrial usher protein Virulence KpGI-5 Protein 4e-137 42
lpfC NP_839216.1 long polar fimbriae Not tested SHI-2 Protein 8e-136 41
lpfC NP_709462.1 long polar fimbriae Not tested SHI-2 Protein 8e-136 41
lpfC YP_006098365.1 fimbrial outer membrane usher protein Not tested Tn2411 Protein 8e-139 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lpfC YP_002238465.1 outer membrane usher protein LpfC VFG0454 Protein 2e-161 45
lpfC YP_002238465.1 outer membrane usher protein LpfC VFG0876 Protein 1e-141 41
lpfC YP_002238465.1 outer membrane usher protein LpfC VFG0446 Protein 2e-139 41