Gene Information

Name : cvrA (KPK_1987)
Accession : YP_002237826.1
Strain : Klebsiella pneumoniae 342
Genome accession: NC_011283
Putative virulence/resistance : Unknown
Product : potassium/proton antiporter
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG3263
EC number : -
Position : 2045790 - 2047523 bp
Length : 1734 bp
Strand : -
Note : the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli

DNA sequence :
TTGGACGCCGCTGCGGTCATTAGTCTGTTTATTCTGGGTTCTGTTTTAGTAACCTGCAGTATCTTATTGAGCTCCTTTTC
TTCGCGCCTTGGCATCCCGATTCTGGTCATCTTTCTGGCCATCGGGATGCTGGCAGGCATTGACGGCATCGGTGGCATCC
CCTTCGACAACTACCCCTTCGCCTATATGGTGAGTAACCTGGCGCTGGCGGTGATCCTGCTGGACGGCGGGATGCGCACC
CAGGCCAGCTCCTTTCGCGTCGCACTATGGCCCGCGCTATCGCTGGCGACGGTCGGGGTACTGATCACCTCGGCGCTGAC
CGGGATGATGGCTGCCTGGCTGTTCAAGCTGGATATGATCGAAGGCCTGCTGATCGGCGCCATTGTCGGCTCCACCGACG
CTGCGGCGGTTTTCTCGCTGCTCGGCGGCAAGGGGCTCAACGAGCGCGTCGGCTCAACGCTGGAGATTGAGTCAGGCAGT
AACGACCCGATGGCCGTCTTCCTGACCATCACCCTGATCGAAATGATCCAGCAGCACCAGACCGGCCTCAGCTGGATGTT
CGCCGTGCATATCATCCAGCAGTTTGGTCTCGGGATCGCCATCGGCCTCGGCGGCGGCTACCTGCTGCTGCAGATGATCA
ACCGTATCGTGCTGCCCGCCGGGCTCTATCCACTGCTGGCGCTGAGCGGCGGGATCATGATTTTTGCCGTCACCACCACC
CTCGACGGCAGCGGTATCCTTGCCGTCTATCTCTGCGGCTTTCTGCTGGGCAACCGGCCGATCCGCAACCGACACGGTAT
CCTGCAGAACTTCGACGGCCTGGCGTGGCTGGCGCAGATCGCCATGTTCCTGGTGCTGGGCCTGCTGGTGACGCCCTCCG
ACCTGCTGCCGATCGCCATCCCGGCGCTGCTGCTGTCGATGTGGATGATTTTCATTGCCCGCCCGCTGTCGGTGTTTGCC
GGCCTGCTGCCGTTTCGCGGCTTTAACCTGCGCGAACGGGTGTTTATCAGCTGGGTTGGCCTGCGCGGCGCGGTGCCCAT
CATTCTCGCGGTGTTCCCGATGATGGCCGGGCTGGACAACGCCCGCTTGTTCTTCAATGTCGCCTTCTTCGTGGTGCTGG
TGTCGCTGCTGCTGCAGGGCACTTCGCTGTCGTGGGCGGCGAAGAAAGCCAAAGTGGTGGTGCCGCCCATCAGCTGGCCC
ATCTCCCGCGTCGGGCTGGATATTCACCCGGAAAACCCGTGGGAGCAGTTTGTCTATCAGCTGGGCGCCGATAAGTGGTG
CATCGGCGCGGCGCTGCGCGATCTGCATATGCCGCCGGAGACGCGGATTGCGGCACTGTTTCGCAACAATGCCCTGCTGC
ACCCCACCGGCAGCACCCGCCTGCGGGAAGGCGATATCCTGTGCGTCATTGGTCGGGAGCACGACCTGCCGGCGCTGGGC
AAAATGTTCAGCCAGTCGCCGCCGGTGGCGCTCGATCAGCGCTTTTTCGGCGACTTTATTCTTGATGCCGAGGCCCGCTT
CGCCGATGTGGCGCAAATCTACGGCCTCGATGGCGGAGAGGAGTTCCGCGAGCATCAGCAGTCGCTCGGGGAAGTGGTGC
AGCAGCTGTTGGGCGCCGCGCCGGTGGTGGGCGACCAGGTGGAGTTCGCCGGGATGGTGTGGACGGTGGCGGAAAAAGAG
AACGATCACGTGCTGAAGGTTGGGGTGCGGGTCGCGGAAGACGAGGCGGAGTGA

Protein sequence :
MDAAAVISLFILGSVLVTCSILLSSFSSRLGIPILVIFLAIGMLAGIDGIGGIPFDNYPFAYMVSNLALAVILLDGGMRT
QASSFRVALWPALSLATVGVLITSALTGMMAAWLFKLDMIEGLLIGAIVGSTDAAAVFSLLGGKGLNERVGSTLEIESGS
NDPMAVFLTITLIEMIQQHQTGLSWMFAVHIIQQFGLGIAIGLGGGYLLLQMINRIVLPAGLYPLLALSGGIMIFAVTTT
LDGSGILAVYLCGFLLGNRPIRNRHGILQNFDGLAWLAQIAMFLVLGLLVTPSDLLPIAIPALLLSMWMIFIARPLSVFA
GLLPFRGFNLRERVFISWVGLRGAVPIILAVFPMMAGLDNARLFFNVAFFVVLVSLLLQGTSLSWAAKKAKVVVPPISWP
ISRVGLDIHPENPWEQFVYQLGADKWCIGAALRDLHMPPETRIAALFRNNALLHPTGSTRLREGDILCVIGREHDLPALG
KMFSQSPPVALDQRFFGDFILDAEARFADVAQIYGLDGGEEFREHQQSLGEVVQQLLGAAPVVGDQVEFAGMVWTVAEKE
NDHVLKVGVRVAEDEAE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AAB61290.1 unknown Not tested PAI I CFT073 Protein 0.0 89
f536 AAC61706.1 F536 Not tested PAI I CFT073 Protein 0.0 89