Gene Information

Name : uvrY (KPK_1869)
Accession : YP_002237711.1
Strain : Klebsiella pneumoniae 342
Genome accession: NC_011283
Putative virulence/resistance : Virulence
Product : response regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG2197
EC number : -
Position : 1933286 - 1933942 bp
Length : 657 bp
Strand : +
Note : in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate v

DNA sequence : 
TTGATCAACGTTCTTCTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAAGGGAT
TAAAGTCGCTGGCGAAGCCTGTTGCGGCGAGGACGCCGTGAAGTGGTGCCGGGCTAATTCCGCAGATGTCGTCCTGATGG
ACATGAACATGCCCGGGATCGGTGGTCTTGAAGCCACGCGCAAAATCGCGCGCTCCGTGGCGGGCACGAAAGTGATCATG
CTCACCGTGCATACCGAGAATCCTCTACCTGCCAAGGTCATGCAGGCGGGGGCGGCGGGCTATCTTAGCAAGGGTGCTGC
ACCGCAGGAAGTGGTGAATGCGATCCGCTGCGTGGCGTCCGGACAACGTTACATTGCCTCCGATATTGCTCAGCAAATGG
CGCTAAGTCAGATTGAACCGGAAAAAACGGAATCGCCGTTTGCCAGTTTGTCTGAACGCGAATTGCAGATTATGCTGATG
ATCACCAAAGGTCAGAAGGTGAATGAGATCTCAGAGCAGCTCAATCTGAGTCCCAAAACGGTTAACAGCTATCGCTACCG
AATGTTCAGCAAATTAAACATTCATGGCGATGTGGAGCTGACCCACCTGGCAATTCGCCATGGCCTGTGTAATGCGGAGT
CGTTAGCAAGCCAGTGA

Protein sequence : 
MINVLLVDDHELVRAGIRRILEDIKGIKVAGEACCGEDAVKWCRANSADVVLMDMNMPGIGGLEATRKIARSVAGTKVIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVNAIRCVASGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAESLASQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00302 YP_008207767.1 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Not tested AbaR25 Protein 5e-47 50
BJAB0868_00306 YP_008211632.1 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Not tested AbaR26 Protein 5e-47 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
uvrY YP_002237711.1 response regulator VFG1889 Protein 3e-54 52