Gene Information

Name : KPK_1842 (KPK_1842)
Accession : YP_002237686.1
Strain : Klebsiella pneumoniae 342
Genome accession: NC_011283
Putative virulence/resistance : Unknown
Product : integrase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0582
EC number : -
Position : 1912830 - 1914098 bp
Length : 1269 bp
Strand : -
Note : identified by match to protein family HMM PF00589

DNA sequence :
ATGTCCCTTAGCGACGCGAAAATCCGCACTCTCAAGCCCACTGATAAACCCTTTAAAGTCGCCGATTCCCACGGTCTGTA
TCTTCTTATCAAACCTGGCGGTTCCCGTCACTGGTATCTCAAGTACCGTATTAACGGTAAAGAATCCCGCATTGCACTGG
GTGCCTATCCTGCCGTCTCCCTGTCTGACGCCCGCCAGCAGCGTGAAGGTATCCGTAAAATGCTGGCGCTTAATATCAAT
CCGGCACAGCAACGTGCCGCTGAACGGGGAGCCTGCACACCGGAGAAGTTGTTTAAAACCGTGGCGCTGGCGTGGCATAA
AAGCAATACAAAATGGTCTAAGAACACCGCCGACCGCCTGCTTGCCAGCCTGAACAATCATGTCTTTCCGGTTATCGGGC
ACCTGTCAGTCTCAGAGCTTAAACCCAGGCATTTCATTGACCTGCTGAAAGGGATTGAGAAAAAAGGCCTGCTGGAAGTG
GCGTCCCGCACGCGGCAGCACCTCAGTAACATCATGCGTTATGCGGTTCATCAGGGGGTAATCGACAGTAACCCGGCGGC
AAACCTTGACGGCGTGACAACACCTCCCGTCAGACGGCATTATCCTGCTCTGCCACTGGAGCGGCTGCCTGAACTGATTG
AACGCATTGACGGTTATCACCAGGGACGGGAACTCACCCGGCTTGCAGTCCTGCTGACGTTGCATGTGTTCATCCGCTCC
AGTGAACTGCGCTTTGCCCGCTGGTCAGAGATTGATTTCAGAAACCGGGTCTGGACGATACCCGGGACACGCGAAGCCAT
TGAAGGCGTACGTTATTCCGGGCGCGGTGCCAAAATGCGCACACCGCATATCGTGCCCCTCTCGGAACAGGCTATCGCCA
TTCTGAAACGGATTAGGGATATCTCCGGTGATGGTGAGCTGGTCTTCCCCGGCGACCATAACCCGTATAAGCCAATGTGT
GAAAACACGGTCAACAAGGCATTGCGCCTGATGGGCTACGACACGAAAAAGGATATCTGTGGCCACGGCTTTCGGGCGAT
GGCATGCAGTGCCCTGATGGAGTCCGGTTTATGGTCGCAGGACGCAGTGGAACGCCAGATGAGTCATCAGGAACGCAACA
CCGTGCGTCTGGCTTACATTCATAAGGCCGAACATCTGGATGCCCGTAAGGCGATGATGCAGTGGTGGTCGGATTATCTG
GATACCTGCCGGGAAGCATATGTGCCGCCGTATATCCAAGGTCAGGAAGACAGCCACAAAGCGGCATAA

Protein sequence :
MSLSDAKIRTLKPTDKPFKVADSHGLYLLIKPGGSRHWYLKYRINGKESRIALGAYPAVSLSDARQQREGIRKMLALNIN
PAQQRAAERGACTPEKLFKTVALAWHKSNTKWSKNTADRLLASLNNHVFPVIGHLSVSELKPRHFIDLLKGIEKKGLLEV
ASRTRQHLSNIMRYAVHQGVIDSNPAANLDGVTTPPVRRHYPALPLERLPELIERIDGYHQGRELTRLAVLLTLHVFIRS
SELRFARWSEIDFRNRVWTIPGTREAIEGVRYSGRGAKMRTPHIVPLSEQAIAILKRIRDISGDGELVFPGDHNPYKPMC
ENTVNKALRLMGYDTKKDICGHGFRAMACSALMESGLWSQDAVERQMSHQERNTVRLAYIHKAEHLDARKAMMQWWSDYL
DTCREAYVPPYIQGQEDSHKAA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
int YP_002346908.1 integrase Not tested HPI Protein 3e-168 88
y2393 NP_669700.1 prophage integrase Not tested HPI Protein 3e-168 88
int2 NP_993013.1 integrase Not tested HPI Protein 3e-168 88
int CAA21384.1 - Not tested HPI Protein 3e-168 88
int CAA08754.1 integrase Not tested HPI Protein 9e-169 88
int CAB59974.1 integrase Not tested HPI Protein 2e-169 88
APECO1_1051 YP_853069.1 phage integrase Not tested PAI IV APEC-O1 Protein 7e-122 87
intB AAD37509.1 P4-like integrase Not tested PAI IV 536 Protein 2e-132 87
unnamed AAD17660.1 unknown Not tested HPI Protein 3e-165 86
SESS1296_03598 AFO66301.1 bacteriophage integrase Not tested SESS LEE Protein 5e-117 61
SESS1635_03816 AFO66367.1 bacteriophage integrase Not tested SESS LEE Protein 5e-117 61
int NP_458759.1 bacteriophage integrase Not tested SPI-7 Protein 4e-115 57
int NP_807963.1 bacteriophage integrase Not tested SPI-7 Protein 4e-115 57
ECO111_3718 YP_003236059.1 putative integrase Not tested LEE Protein 3e-107 56
int AAK16198.1 Int Not tested PAI-I AL862 Protein 3e-109 56
int ADD91747.1 P4 integrase Not tested PAI-I AL862 Protein 3e-109 56
ECUMN_3322 YP_002414004.1 integrase Not tested Not named Protein 4e-107 56
ORF_1 AAZ04412.1 phage integrase Not tested PAI I APEC-O1 Protein 2e-106 55
S4822 NP_838459.1 P4-type integrase Not tested SHI-1 Protein 2e-107 55
SF2964 NP_708738.1 P4-type integrase Not tested SHI-1 Protein 2e-107 55
APECO1_3534 YP_854214.1 P4-like integrase Not tested PAI I APEC-O1 Protein 2e-106 55
c5216 NP_757064.1 prophage P4 integrase Not tested PAI II CFT073 Protein 1e-106 55
int AAK00456.1 Int Not tested SHI-1 Protein 4e-99 55
ECO103_3550 YP_003223418.1 integrase Not tested LEE Protein 2e-107 55
int-phe AAL57571.1 CP4-like integrase Not tested LEE Protein 1e-107 55
ECO26_5300 YP_003232178.1 integrase Not tested LEE Protein 2e-107 55
int AAL51028.1 CP4-like integrase Not tested LEE Protein 1e-107 55
int-phe AAL60261.1 Int-phe Not tested LEE Protein 1e-107 55
int AAT48697.1 CP4-like integrase Not tested PAI I 4787 Protein 8e-108 55
c3556 NP_755431.1 prophage P4 integrase Not tested PAI I CFT073 Protein 1e-107 55
int AAL51003.1 CP4-like integrase Not tested LEE Protein 7e-108 55
Z4313 NP_289539.1 pathogenicity island integrase Not tested OI-122 Protein 8e-107 55
intP4 CAE85151.1 CP4 integrase protein Not tested PAI V 536 Protein 1e-108 55
int CAC81896.1 integrase Not tested LEE II Protein 4e-99 55
intB CAD42017.1 bacteriophage P4 integrase Not tested PAI II 536 Protein 4e-100 54
unnamed ABR13507.1 phage integrase Not tested PAGI-6 Protein 4e-92 51
STY4821 NP_458899.1 integrase Not tested SPI-10 Protein 5e-96 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
KPK_1842 YP_002237686.1 integrase VFG0626 Protein 7e-108 55
KPK_1842 YP_002237686.1 integrase VFG1693 Protein 5e-108 55
KPK_1842 YP_002237686.1 integrase VFG1536 Protein 2e-100 54