Gene Information

Name : KPK_1811 (KPK_1811)
Accession : YP_002237656.1
Strain : Klebsiella pneumoniae 342
Genome accession: NC_011283
Putative virulence/resistance : Unknown
Product : integrase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0582
EC number : -
Position : 1879467 - 1880735 bp
Length : 1269 bp
Strand : -
Note : identified by match to protein family HMM PF00589

DNA sequence : 
ATGTCCCTTACCGATGCGAAAATCCGCACCCTCAAACCTTCTGATAAACCCTTTAAAGTCTCCGATTCTCACGGTCTGTA
TATTCTTGTCAAACCGGGCGGCTCACGTCACTGGTATCTCAAGTACCGTATTAATGGTAAAGAATCTCGCCTCGGTTTAG
GTGCTTATCCTAATGTTTCTCTGACCGACGCCCGGCAACAGCGTGACGACATCCGTAAGCTACTTGCACAGAAGATAAAC
CCGGCACAACAGCGTCTCACTGAAAAGGCAGCCCGGTCACCGGAAAAAGCCTTCAAAGCCGTAGCTCTGAACTGGCATAA
AAGCAATAAAACCTGGTCGGAAGATCACGCCAATCGCGTGCTTGGCCGTATGAACAACCACATTTTCCCGATAATTGGTC
ATCTGACGGTAACAGAACTGAAAGTTCAGCACTTCATCAATCTGCTGAAAGGCGTTGAGAATAAAGGTTTGCTGGAAATA
GCTTCTCGTACCCGACAATACATAAGCAGCATTATGCGGCACGCCTTACATCAGGGGTTGATTGAACACAACCCGGCTGC
AGACTTGAAAGGCGTCACCGTTCCGCCCATCAAACGTCACTATCCTGCCCTGCCCCTGGAACGTCTGCCGGAACTGCTGA
AACGCATTGACGACTACAAACAGGGACGGGAGTTAACTCAGTTGGCAATCATGCTATCTCTTCATGTGTTTATCCGTTCC
AGTGAACTGCGTTTTGCCCGTTGGCCGGAGATTAATTTCAGAAACAGGCTCTGGACTATCCCCGCTACCCGAGAAACAAT
TCCCAATGTTCGCAACTCTGGGCGAGGTGCAAAAATGCGTGCGCAGCATATTGTGCCACTTTCCCAACAGGCCATCGACA
TTCTCAAACAGATCAGAGAAATCTCTGGTGATCAGGTACTGATATTCCCCAGCATTCGTGATCCGTATAAACCAATGAGT
GAAAATACGATTAATAAGGCTTTACGGCTAATGGATTATGATACTAAAGAGGATGTCTGCGGCCACGGATTCCGGGCAAT
GGCCTGTAGCGCCCTGATTGAGTCCGGCCTGTGGTCAGAGGATGCCATTGAAAGGCAGATGAGTCATCAGGAGCGTAACA
GCGTGCGAGCAGCGTACATACATAAAGCGGAGCACCTGGAAGCGCGTAAAGCAATGATGCAATGGTGGTCAGATTATATA
GATGAATGCAGGGAAAAATATGTTCCCCCCTATAATTGGAGCAGTCAGAAAAATAATCATGCTGCCTAA

Protein sequence : 
MSLTDAKIRTLKPSDKPFKVSDSHGLYILVKPGGSRHWYLKYRINGKESRLGLGAYPNVSLTDARQQRDDIRKLLAQKIN
PAQQRLTEKAARSPEKAFKAVALNWHKSNKTWSEDHANRVLGRMNNHIFPIIGHLTVTELKVQHFINLLKGVENKGLLEI
ASRTRQYISSIMRHALHQGLIEHNPAADLKGVTVPPIKRHYPALPLERLPELLKRIDDYKQGRELTQLAIMLSLHVFIRS
SELRFARWPEINFRNRLWTIPATRETIPNVRNSGRGAKMRAQHIVPLSQQAIDILKQIREISGDQVLIFPSIRDPYKPMS
ENTINKALRLMDYDTKEDVCGHGFRAMACSALIESGLWSEDAIERQMSHQERNSVRAAYIHKAEHLEARKAMMQWWSDYI
DECREKYVPPYNWSSQKNNHAA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
int CAB59974.1 integrase Not tested HPI Protein 2e-159 76
int YP_002346908.1 integrase Not tested HPI Protein 2e-157 75
y2393 NP_669700.1 prophage integrase Not tested HPI Protein 2e-157 75
int2 NP_993013.1 integrase Not tested HPI Protein 2e-157 75
int CAA21384.1 - Not tested HPI Protein 2e-157 75
int CAA08754.1 integrase Not tested HPI Protein 5e-158 75
unnamed AAD17660.1 unknown Not tested HPI Protein 2e-154 74
intB AAD37509.1 P4-like integrase Not tested PAI IV 536 Protein 2e-122 72
APECO1_1051 YP_853069.1 phage integrase Not tested PAI IV APEC-O1 Protein 2e-111 71
SESS1296_03598 AFO66301.1 bacteriophage integrase Not tested SESS LEE Protein 3e-118 58
SESS1635_03816 AFO66367.1 bacteriophage integrase Not tested SESS LEE Protein 3e-118 58
int NP_807963.1 bacteriophage integrase Not tested SPI-7 Protein 1e-117 57
int NP_458759.1 bacteriophage integrase Not tested SPI-7 Protein 1e-117 57
ECO111_3718 YP_003236059.1 putative integrase Not tested LEE Protein 5e-110 55
SF2964 NP_708738.1 P4-type integrase Not tested SHI-1 Protein 2e-110 55
APECO1_3534 YP_854214.1 P4-like integrase Not tested PAI I APEC-O1 Protein 2e-110 55
c5216 NP_757064.1 prophage P4 integrase Not tested PAI II CFT073 Protein 1e-110 55
ORF_1 AAZ04412.1 phage integrase Not tested PAI I APEC-O1 Protein 1e-110 55
S4822 NP_838459.1 P4-type integrase Not tested SHI-1 Protein 2e-110 55
intB CAD42017.1 bacteriophage P4 integrase Not tested PAI II 536 Protein 5e-105 55
int AAK00456.1 Int Not tested SHI-1 Protein 7e-102 55
int AAL51028.1 CP4-like integrase Not tested LEE Protein 1e-111 55
int-phe AAL60261.1 Int-phe Not tested LEE Protein 1e-111 55
intP4 CAE85151.1 CP4 integrase protein Not tested PAI V 536 Protein 1e-111 55
int AAT48697.1 CP4-like integrase Not tested PAI I 4787 Protein 3e-110 55
int AAL51003.1 CP4-like integrase Not tested LEE Protein 2e-110 55
Z4313 NP_289539.1 pathogenicity island integrase Not tested OI-122 Protein 8e-111 55
ECO103_3550 YP_003223418.1 integrase Not tested LEE Protein 2e-111 55
ECUMN_3322 YP_002414004.1 integrase Not tested Not named Protein 8e-109 55
int AAK16198.1 Int Not tested PAI-I AL862 Protein 2e-111 55
ECO26_5300 YP_003232178.1 integrase Not tested LEE Protein 2e-111 55
c3556 NP_755431.1 prophage P4 integrase Not tested PAI I CFT073 Protein 1e-109 55
int ADD91747.1 P4 integrase Not tested PAI-I AL862 Protein 2e-111 55
int-phe AAL57571.1 CP4-like integrase Not tested LEE Protein 1e-111 55
int CAC81896.1 integrase Not tested LEE II Protein 5e-103 55
STY4821 NP_458899.1 integrase Not tested SPI-10 Protein 1e-95 50
unnamed ABR13507.1 phage integrase Not tested PAGI-6 Protein 3e-96 50
unnamed AFX83955.1 integrase Not tested SE-PAI Protein 2e-68 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
KPK_1811 YP_002237656.1 integrase VFG0626 Protein 9e-111 55
KPK_1811 YP_002237656.1 integrase VFG1536 Protein 3e-105 55
KPK_1811 YP_002237656.1 integrase VFG1693 Protein 5e-110 55