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Name : guaA (KPK_1284) Accession : YP_002237144.1 Strain : Klebsiella pneumoniae 342 Genome accession: NC_011283 Putative virulence/resistance : Unknown Product : GMP synthase Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0519 EC number : - Position : 1307173 - 1308750 bp Length : 1578 bp Strand : + Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway DNA sequence : ATGACGGAAAACATTCATAAACATCGCATTCTCATTCTCGACTTCGGCTCTCAGTATACTCAGCTGGTGGCGCGTCGCGT GCGTGAGCTGGGCGTCTACTGTGAGCTGTGGGCGTGGGATGTCACAGAAGCACAGATCCGCGAATTCAATCCAAGCGGCA TCATTCTTTCCGGCGGCCCGGAAAGTACTACCGAAGAGAACAGCCCGCGCGCGCCGCAGTATGTGTTTGAAGCCGGCGTG CCGGTATTTGGCGTCTGCTACGGCATGCAGACCATGGCGATGCAACTGGGCGGCCATGTGGAAGGTTCTAACGAGCGTGA GTTTGGCTACGCGCAGGTTGAAGTGGTTAACGACAGCGCGCTGGTGCGCGGTATCGAAGACTCCCTGACCGCAGACGGTA AACCGCTGCTGGACGTGTGGATGAGCCACGGCGACAAGGTCACCGCCATCCCGTCTGACTTCGTCACCGTCGCCAGCACC GACAACTGCCCGTTCGCCATTATGGCCAACGAAGAAAAACGCTTCTACGGCGTGCAGTTCCACCCGGAAGTGACCCACAC CCGTCAGGGGATGCGTATGCTGGAGCGCTTCGTGCGCGACATCTGCCAGTGCGAAGCCCTGTGGACCCCGGCGAAAATCA TCGACGACGCCGTCGAGCGTATCCGCCAGCAGGTTGGCGATGACAAAGTGATCCTTGGCCTCTCCGGCGGCGTGGACTCC TCAGTGACCGCGATGTTGCTGCACCGCGCCATCGGCAAAAACCTGACCTGCGTATTCGTGGATAACGGCCTCCTGCGTCT GAATGAAGCGCAGCAGGTGATGGACATGTTTGGCGACCACTTTGGCCTGAACATTGTTCACGTTGAAGGCGAGCAGCGCT TCCTCGATGCGCTGAAAGGCGAGAACGATCCGGAAGCGAAACGTAAAATCATCGGCCGCGTCTTCGTGGAAGTGTTCGAC GAAGAAGCGCTGAAGCTGGACGACGTCAAATGGCTGGCGCAGGGTACCATCTACCCTGACGTTATCGAATCTGCCGCTTC CGCTACCGGTAAAGCACACGTCATTAAATCTCACCACAATGTGGGCGGCCTGCCGAAAGAGATGAAGATGGGGCTGGTTG AGCCGCTGCGTGAGCTGTTCAAAGACGAAGTGCGTAAGATCGGTCTGGAACTGGGCCTGCCGTACGATATGCTCTACCGT CACCCGTTCCCGGGCCCGGGCCTCGGCGTGCGCGTGCTGGGCGAAGTGAAGAAAGAGTACTGCGACCTGCTGCGTCGTGC GGACGCTATCTTCATCGAAGAGCTGCACAAAGCTGACCTGTACAACAAAGTGAGCCAGGCGTTTACCGTGTTCCTGCCGG TGCGCTCCGTCGGCGTAATGGGCGATGGCCGTAAATACGACTGGGTCGTTTCCCTGCGTGCAGTGGAAACCATCGACTTT ATGACCGCGCACTGGGCGCACCTGCCGTATGATTTCCTCGGCCGCGTCTCTAACCGCATTATCAATGAAGTGAACGGTAT CTCCCGCGTGGTGTATGACATCAGCGGTAAGCCGCCAGCAACGATTGAGTGGGAATGA Protein sequence : MTENIHKHRILILDFGSQYTQLVARRVRELGVYCELWAWDVTEAQIREFNPSGIILSGGPESTTEENSPRAPQYVFEAGV PVFGVCYGMQTMAMQLGGHVEGSNEREFGYAQVEVVNDSALVRGIEDSLTADGKPLLDVWMSHGDKVTAIPSDFVTVAST DNCPFAIMANEEKRFYGVQFHPEVTHTRQGMRMLERFVRDICQCEALWTPAKIIDDAVERIRQQVGDDKVILGLSGGVDS SVTAMLLHRAIGKNLTCVFVDNGLLRLNEAQQVMDMFGDHFGLNIVHVEGEQRFLDALKGENDPEAKRKIIGRVFVEVFD EEALKLDDVKWLAQGTIYPDVIESAASATGKAHVIKSHHNVGGLPKEMKMGLVEPLRELFKDEVRKIGLELGLPYDMLYR HPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELHKADLYNKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDF MTAHWAHLPYDFLGRVSNRIINEVNGISRVVYDISGKPPATIEWE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| guaA | YP_001331415.1 | GMP synthase | Not tested | vSa¥á | Protein | 6e-128 | 51 |
| SAMSHR1132_03620 | YP_005324884.1 | GMP synthase | Not tested | vSa¥á | Protein | 3e-128 | 51 |
| SAPIG0468 | YP_005733278.1 | GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) | Not tested | SAPI-S0385 | Protein | 3e-128 | 51 |
| guaA | NP_938969.1 | GMP synthase | Not tested | Not named | Protein | 2e-111 | 47 |
