Gene Information

Name : olgA (KPK_1140)
Accession : YP_002237004.1
Strain : Klebsiella pneumoniae 342
Genome accession: NC_011283
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 1151480 - 1153000 bp
Length : 1521 bp
Strand : +
Note : identified by similarity to GB:BAA24014.1; match to protein family HMM PF00171

DNA sequence :
ATGCGTTATGCACATCCTGGCCAGCCCGGCGCCCTGGTTTCATTTAAATCCGCTTACGGCAACTTCATTGACGGTAAATT
TGTCGAGCCGCTGAGCGGTGAATTCTTTATGAATACCTCCCCGGTCGACGGCAGCAACATTGCGCAGTTTCCCCGCTCGG
ACGCCAAAGACATTGAGTTCGCCCTCGATGCCGCTCACCGTGCGGCGCCGGCGTGGGGTAAAACGTCAGTGCAGCAGCGC
TCCAGGCTGCTGCTACAGGTCGCCGATCGTATTGAACAGCACCTGGAGTATCTGGCCGTCGCGGAGAGCTGGGACAACGG
GAAACCGATCCGCGAAACCCTGAATGCCGACCTGCCGCTGGCGGTGGACCATTTCCGCTACTTCGCCGGCTGCCTGCGCG
CCCAGGAGGGAAGCACCGCCGAGATTGACGAAACGACGGTGGCCTATCATTTCCATGAACCGCTGGGGGTGGTCGGGCAG
ATTATCCCGTGGAACTTTCCGCTGCTGATGGCCGCGTGGAAGCTGGCCCCGGCCCTGGCGGCGGGTAACTGCGTGGTGCT
CAAGCCGGCTGAACAGACGCCGCTGAGCATTACCCTGCTGCTGGAGCTGATCGGCGATCTGTTCCCGGCCGGGGTGCTTA
ACGTGGTACAGGGATTCGGCAAAGAGGCAGGCGAGGCGCTGGCCACCAGCAAGCGTATCGCCAAGCTGGCGTTCACTGGC
TCCACGCCGGTCGGGCGGCATATTCTCGCCTGCGCGGCGGAAAATATTATCCCCTGCACTGTCGAGCTGGGGGGCAAATC
GCCCAACATCTACTTCGCCGACGTAATGGAGGGAGAAGAGGAGTTTATTGAGAAGGCGGTGGAGGGACTGGTGCTTGGCT
TCTTCAACCAGGGGGAGGTATGTACCTGCCCGTCGCGGGCGCTGATCCATGAATCCATCTATGAGCCCTTTATGGCGCGG
GTCATGGAGAAGGTGGCGCAGATCCGCCGTGGTGACCCGTTAGATACCGACACCATGATCGGCGCGCAGGCTTCCCGCCA
GCAGTTCGATAAGATCCTCTCCTACATTCAGATTGCGCGGGAAGAGGGCGGGCAAATTCTGACCGGCGGCGAGCGGGCGG
CTATCGCGCCGGCGCTGGATAACGGGTTTTATATTCAGCCCACGCTGATTAAAGGCCGCAACGATATGCGCAGCTTCCAG
GAGGAGATCTTTGGGCCCGTGATCGGGGTGACCACCTTTAAGGACGAAGCGGAAGCGCTGACCATCGCCAATGAGACCCA
GTTTGGCCTTGGCGCCGGGGTCTGGACGCGGGATACCAACCTCGCCTATCGCATGGGTCGCGGGATTAAAGCCGGCCGCG
TATGGACCAACTGCTATCATGTCTACCCGGCGCATGCGGCGTTCGGCGGCTATAAACAGTCTGGCGTTGGCCGGGAAACG
CACAAGATGGCGCTGGATGCTTACCAGCAAACCAAAAACCTGCTGGTGAGCTACGGCACCGCGCCGCTGGGCCTGTTCTA
A

Protein sequence :
MRYAHPGQPGALVSFKSAYGNFIDGKFVEPLSGEFFMNTSPVDGSNIAQFPRSDAKDIEFALDAAHRAAPAWGKTSVQQR
SRLLLQVADRIEQHLEYLAVAESWDNGKPIRETLNADLPLAVDHFRYFAGCLRAQEGSTAEIDETTVAYHFHEPLGVVGQ
IIPWNFPLLMAAWKLAPALAAGNCVVLKPAEQTPLSITLLLELIGDLFPAGVLNVVQGFGKEAGEALATSKRIAKLAFTG
STPVGRHILACAAENIIPCTVELGGKSPNIYFADVMEGEEEFIEKAVEGLVLGFFNQGEVCTCPSRALIHESIYEPFMAR
VMEKVAQIRRGDPLDTDTMIGAQASRQQFDKILSYIQIAREEGGQILTGGERAAIAPALDNGFYIQPTLIKGRNDMRSFQ
EEIFGPVIGVTTFKDEAEALTIANETQFGLGAGVWTRDTNLAYRMGRGIKAGRVWTNCYHVYPAHAAFGGYKQSGVGRET
HKMALDAYQQTKNLLVSYGTAPLGLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-154 66
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 1e-160 64
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 1e-160 64
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 1e-160 64
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 7e-160 64
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 2e-57 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
olgA YP_002237004.1 aldehyde dehydrogenase VFG0082 Protein 5e-155 66