Gene Information

Name : nrdE (KPK_1121)
Accession : YP_002236985.1
Strain : Klebsiella pneumoniae 342
Genome accession: NC_011283
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit alpha
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0209
EC number : -
Position : 1137403 - 1139544 bp
Length : 2142 bp
Strand : -
Note : Catalyzes the rate-limiting step in dNTP synthesis

DNA sequence :
TTGGCAACGACAACCGCAGAACGTATAACCGCCGCGGCGGATTTTCACGCCCTCAACGCGATGCTGAATTTGTACGACAG
CGAGGGCCGCATCCCGTTTGAGAAAGATCGCCAGGCGGTGGAGGTCTTTATGACCACCCAGATACAGCCCAACACCCTCA
GTTTTGCCAGCCAGGAGGATAAACTCACCTGGCTCGTCCGCGAGGGCTATTACGATCCGCAGGTACTGGCCGGCTATGAC
CGCGCGTTTGTGCTGGCATTGTTCGCCCATGCCCGGCGCGCCGCGTTTCGCTTTCAGACCTTCCTCGGCGCCTGGAAGTT
CTATACCAGCTACGCGCTGAAGACCTTTGACGGCAAGCACTACCTCGAGGATTTTGCCGATCGCTGCGTAATGGTGGCAC
TGACGCTGGCCCAGGGGGATGACCAGCAGGCGCGGCAGCTAATGGAAGAGATGCTCAGCGGCCGCTTCCAGCCCGCGACC
CCCACCTTCCTCAACGCCGGCAAGCAGCAGCGCGGGGAGCTGATCTCCTGCTTCCTGCTGCGCATTGAAGATAATATGGA
ATCCATCGGCCGGGCGGTTAACTCGGCGCTGCAGCTGTCGAAGCGCGGCGGCGGCGTGGCCTTTTTACTCTCCAACCTGC
GCGAGGCCGGGGCGCCGATCAAGCGCATCGAAAATCAGTCCTCCGGGGTGGTGCCGGTGATGAAGATGCTGGAGGACGCC
TTCTCCTATGCCAACCAGCTTGGCGCCCGCCAGGGGGCGGGAGCGGTCTGGCTGCATGCGCACCATCCCGATATTTTGCG
CTTCCTCGATACCCGGCGTGAGAATGCCGATGAGAAAATCCGCATCAAAACCTTGTCGCTGGGAGTGGTGATCCCCGATA
TCACCTTCCAGCTGGCAAAAGAAGACGCGCAGATGGCCCTGTTCTCGCCGTATGACGTCGAGCGGCTGTACGGTAAACCC
TTCGCCGACTGCGCCATCGGCGATCTCTATCCGCAGCTGGTGGCCGACGAACGGGTCCGCAAGCGCTGGATCCGCGCCCG
CGACCTTTTCCAGCGCCTGGCGGAGATCCAGTTTGAATCCGGCTATCCGTACATCATGTTTGAAGATACCGTCAATCGCG
CCAATCCGGTGGCCGGACGGATCACCATGAGCAATCTGTGTTCGGAAATTCTGCAGGTCAGTACGCCATCCACCTATGAT
GAGAACCTCAGTTACGCCCATATCGGCGAGGATATCTCCTGCAACCTCGGCTCGCTGAACATCGCCCATACCATGGACTC
GCCGGATTTTGCCCGCACTATCGCCACCGCGGTGCGCGCCCTGACCGCGGTATCCGATATGAGCGACATACAGTCGGTTC
CCTCGGTGGCGGCCGGCAATGCGGCCTCCCACGCCATCGGCCTGGGGCAGATGAATCTGCACGGCTACCTGGCGCGAGAA
GGGATTGCCTACGGCAGTCCGGAGGGGCTGGACTTCACCAATATCTATTTTTACACCGTGACCTGGCATGCCCTGCACAC
CTCGATGCTGCTGGCCCGCGAGCGCGGCCAGCGCTTCGCTGGCTTCGAACAGTCACGCTACGCCAGCGGGGCGTACTTCG
ACAAATATCTGCAGGAGGAGTGGCAGCCGAAAACCGAACGGGTGCGCGCACTGTTCGCCCGCGCCGGTATCCCCCTGCCC
GACCGGGAAAGCTGGCGCCAGCTGCGCGACGATGTCATGCGCTATGGCATCTATAACCGTTATCTGCAGGCGGTGCCGCC
CACCGGGTCGATCTCGTACATCAACCATGCCACCTCCAGCATTCATCCGATCGTCTCGAAGATTGAGATCCGCAAAGAGG
GGAAGACCGGGCGGGTGTACTACCCCGCGCCGTTTATGAATAACGACAATCTGGCCCTTTATCAGGATGCGTACGAGATA
GGGCCCCAGAAGATCATTGACACCTACGCCGAGGCGACGCGCCACGTCGATCAGGGACTGTCGTTGACGCTGTTCTTCCC
GGATACCGCCACCACCCGCGATATCAACAAGGCGCAAATCTACGCCTGGAAGAAAGGCATTAAGACCCTCTACTACATCC
GTCTGCGCCAGCTGGCGCTGGAAGGCACTGAAATTGAAGGCTGCGTGTCCTGCGCACTGTAA

Protein sequence :
MATTTAERITAAADFHALNAMLNLYDSEGRIPFEKDRQAVEVFMTTQIQPNTLSFASQEDKLTWLVREGYYDPQVLAGYD
RAFVLALFAHARRAAFRFQTFLGAWKFYTSYALKTFDGKHYLEDFADRCVMVALTLAQGDDQQARQLMEEMLSGRFQPAT
PTFLNAGKQQRGELISCFLLRIEDNMESIGRAVNSALQLSKRGGGVAFLLSNLREAGAPIKRIENQSSGVVPVMKMLEDA
FSYANQLGARQGAGAVWLHAHHPDILRFLDTRRENADEKIRIKTLSLGVVIPDITFQLAKEDAQMALFSPYDVERLYGKP
FADCAIGDLYPQLVADERVRKRWIRARDLFQRLAEIQFESGYPYIMFEDTVNRANPVAGRITMSNLCSEILQVSTPSTYD
ENLSYAHIGEDISCNLGSLNIAHTMDSPDFARTIATAVRALTAVSDMSDIQSVPSVAAGNAASHAIGLGQMNLHGYLARE
GIAYGSPEGLDFTNIYFYTVTWHALHTSMLLARERGQRFAGFEQSRYASGAYFDKYLQEEWQPKTERVRALFARAGIPLP
DRESWRQLRDDVMRYGIYNRYLQAVPPTGSISYINHATSSIHPIVSKIEIRKEGKTGRVYYPAPFMNNDNLALYQDAYEI
GPQKIIDTYAEATRHVDQGLSLTLFFPDTATTRDINKAQIYAWKKGIKTLYYIRLRQLALEGTEIEGCVSCAL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1481 YP_001800875.1 ribonucleotide-diphosphate reductase subunit alpha Not tested Not named Protein 0.0 70