Gene Information

Name : nrdF (KPK_1120)
Accession : YP_002236984.1
Strain : Klebsiella pneumoniae 342
Genome accession: NC_011283
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit beta
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0208
EC number : -
Position : 1136430 - 1137392 bp
Length : 963 bp
Strand : -
Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE

DNA sequence :
ATGACCCATTTAACGCGCATCAGCGCTATCAACTGGAACCGCATTGATGACGACAAAGATCTTGAGGTCTGGAATCGTCT
CACCAGCAACTTCTGGCTACCGGAGAAAGTGCCGCTGTCAAACGACATTCCCGCCTGGCAAACCCTCAGTGCGGCGGAGC
AGCAGTTGACCATTCGCGTCTTCACCGGGCTGACGCTGCTCGACACCATTCAGAACACGGTCGGCGCCCCGGCGCTGATG
GCGGACTCCCTGACCCCGCATGAGGAGGCGGTACTGTCGAACATCAGCTTTATGGAAGCGGTTCATGCCCGCTCTTACAG
CTCCATTTTTTCCACGCTGTGCCACAGCAAAGAGGTGGATGCCGCCTTCGCCTGGAGTGAAAGCTGCGAACCCCTGCAGC
GCAAGGCGCAACTGATGCTGGGCTACTATCAGGCCGACGAGCCGCTGAAGAAAAAAATCGCCAGCGTGTTCCTCGAATCC
TTTCTCTTCTACTCCGGCTTCTGGCTGCCAATGCACTTCTCCAGCCGGGGAAAACTGACCAATACCGCGGATCTGATCCG
TCTGATCATTCGCGATGAAGCGGTACATGGCTATTACATTGGCTACAAGTATCAGAAAGGACTGGAGATCGTCAGCCCCG
GAAAGCGCGAAGAACTGAAAAATTTCGCCCTCGATCTGCTGATGGATCTTTATGACAACGAGCTGGCTTACAGTCGGGAA
CTGTACGGCGAGAGCGGCTGGTTTGACGACGTCAGCGCTTTCCTGTGCTACAACGCCAACAAAGCGCTGATGAACCTCGG
TTATGAAGCGCTGTTTCCGGCGGAGATGGCAGCGGTTAACCCGGCGATCCTCGCCGCGCTGTCGCCTAACGCCGATGAAA
ACCACGACTTTTTCTCCGGCTCCGGCTCCTCGTACGTGATAGGCAAAACGGAAGAAACCGACGACGACGATTGGGACTTT
TAA

Protein sequence :
MTHLTRISAINWNRIDDDKDLEVWNRLTSNFWLPEKVPLSNDIPAWQTLSAAEQQLTIRVFTGLTLLDTIQNTVGAPALM
ADSLTPHEEAVLSNISFMEAVHARSYSSIFSTLCHSKEVDAAFAWSESCEPLQRKAQLMLGYYQADEPLKKKIASVFLES
FLFYSGFWLPMHFSSRGKLTNTADLIRLIIRDEAVHGYYIGYKYQKGLEIVSPGKREELKNFALDLLMDLYDNELAYSRE
LYGESGWFDDVSAFLCYNANKALMNLGYEALFPAEMAAVNPAILAALSPNADENHDFFSGSGSSYVIGKTEETDDDDWDF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1479 YP_001800873.1 ribonucleoside-diphosphate reductase subunit beta Not tested Not named Protein 7e-106 67