Gene Information

Name : afeA (KPK_1044)
Accession : YP_002236913.1
Strain : Klebsiella pneumoniae 342
Genome accession: NC_011283
Putative virulence/resistance : Virulence
Product : iron ABC transporter periplasmic iron-binding protein
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG0803
EC number : -
Position : 1061382 - 1062299 bp
Length : 918 bp
Strand : -
Note : identified by similarity to GB:ABC70487.1; match to protein family HMM PF01297

DNA sequence : 
ATGCTACACCTGACACCGCTGAAATCATTGCTGCTGGCCAGCGCGCTGGCTCTGCTGGCCGCGACGCCGGCCACCGCGCA
GGAGAAATTCAGGGTTATCACTACCTTCACGGTTATCGCCGATATGGCGCAGAACGTGGCCGGCGACGCCGCCGACGTCA
GCTCCATCACCAAACCGGGCGCGGAGATCCACGATTACCAGCCCACGCCAGGCGATATCAAACGCGCGCAGGGGGCGCAG
CTGATCCTCAGCAATGGGCTTAATCTCGAACGGTGGTTTGCCCGTTTTTATCAGCACTTACAGGGCGTTCCGGAGGTGGT
AGTCAGCGAGGGGATCCAGCCGATGGGCATCAGCGCGGGCCCCTATAGTGGGAAGCCCAATCCCCATGCCTGGATGTCTG
CAGATAACGCCCTGATCTATGTCGATAACATTCGCGATGCGCTGGTGAAGTACGATCCGCCTCACGCCGACACCTATCGC
CGTAACGCCGAGGCCTATAAGGAGAAGATCCGCCAGACGATGGCGCCGCTGCAGGCCAGACTGGCGCAGCTGCCGGCGGA
TAAGCGCTGGCTGGTCACCAGCGAGGGGGCCTTCTCCTATCTGGCCCGCGACTATGGTCTGCGCGAACTGTATCTGTGGC
CGATCAATGCCGACCAGCAGGGCACCCCGCAACAGGTGCGCAAGGTTATCGACACCATGAAGAAAGAACGCATCCCGACC
ATCTTCAGCGAAAGCACCATCTCCGATAAACCGGCGCGTCAGGTGGCGCGCGAAGCCGGGGCCCACTACGGCGGCGTGTT
GTATGTCGATTCGCTGAGCGCCGCCGACGGCCCGGTGCCGACCTGGCTCGACCTGCTGCGCGTCACCACCGAAACCATCG
TCAACGGTATCCAGGACGGGATGAGGAAGCAGCCATGA

Protein sequence : 
MLHLTPLKSLLLASALALLAATPATAQEKFRVITTFTVIADMAQNVAGDAADVSSITKPGAEIHDYQPTPGDIKRAQGAQ
LILSNGLNLERWFARFYQHLQGVPEVVVSEGIQPMGISAGPYSGKPNPHAWMSADNALIYVDNIRDALVKYDPPHADTYR
RNAEAYKEKIRQTMAPLQARLAQLPADKRWLVTSEGAFSYLARDYGLRELYLWPINADQQGTPQQVRKVIDTMKKERIPT
IFSESTISDKPARQVAREAGAHYGGVLYVDSLSAADGPVPTWLDLLRVTTETIVNGIQDGMRKQP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sitA NP_806464.1 iron transporter periplasmic-binding protein Virulence SPI-1 Protein 4e-108 84
sitA NP_461782.1 periplasmic binding protein Virulence SPI-1 Protein 4e-108 84
sitA AAD41065.1 SitA Virulence centisome 63 pathogenicity island Protein 3e-108 84
sitA YP_217781.1 iron transporter: fur regulated Virulence SPI-1 Protein 4e-108 84
sitA NP_457255.1 Iron transport protein, periplasmic-binding protein Virulence SPI-1 Protein 4e-108 84

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
afeA YP_002236913.1 iron ABC transporter periplasmic iron-binding protein BAC0349 Protein 2e-108 84
afeA YP_002236913.1 iron ABC transporter periplasmic iron-binding protein BAC0439 Protein 1e-85 66

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
afeA YP_002236913.1 iron ABC transporter periplasmic iron-binding protein VFG0525 Protein 2e-108 84