Gene Information

Name : afeC (KPK_1042)
Accession : YP_002236911.1
Strain : Klebsiella pneumoniae 342
Genome accession: NC_011283
Putative virulence/resistance : Virulence
Product : iron ABC transporter permease AfeC
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1108
EC number : -
Position : 1059719 - 1060567 bp
Length : 849 bp
Strand : -
Note : identified by similarity to GB:AAU94304.1; match to protein family HMM PF00950; match to protein family HMM PF01032

DNA sequence : 
ATGAGCTGGCTGCTGGAGCCGTTTGGCTATCACTATATGCTCAATGCGATGTGGGTGTCGGCGCTGGTGGGCGGCGTCTG
CGCGTTTCTCTCCTGCTACCTGATGCTGAAGGGCTGGTCGCTGATTGGCGACGCCCTCTCCCACTCGATTGTGCCCGGCG
TCGCCGGGGCCTATATGCTCGGCCTGCCTTTCGCGCTCGGCGCGTTTCTCTCCGGCGGCCTGGCGGCGGGCAGCATGCTG
TTTTTGCAGCAGCGCTCGCGGCTGAAAGAGGATGCCATTATTGGCCTGATCTTCTCCTCCTTCTTCGGGATCGGGCTGTT
TATGGTGTCGCTAAATCCGACGTCGGTGAATATCCAGACCATTATCCTCGGCAATATTCTGGCCATCGCCCCGGAGGATA
TTATCCAGCTGGCGGCGATCGGCTTTATCTCGATGGCGATCCTGCTGCTGAAGTGGAAAGATCTGATGGTGACCTTCTTT
GATGAAAACCATGCCCGCTCGATTGGCCTGAACACCCGCGGCCTGAAGCTGCTGTTCTTTACCCTGCTGGCCGCCTGCAC
CGTGGCGGCGCTGCAGACCGTCGGCGCCTTTCTGGTCATCTGCCTGGTGGTGACTCCCGGGGCCACCGCGTGGCTGTTAA
CCGACCGCTTTCCGCGCCTGCTGGCCATCGCCGTGGCTATCGGCAGTCTGACCAGTTTCTTCGGCGCCTGGCTCAGCTAC
TATCTCGACGGCGCCACCGGCGGCATTATCGTGGTCGCGCAAACGCTGTTGTTCCTCATCACCTTTATCTTCGCGCCGAA
GCACGGCCTGCTGGCCAGCCGCCGCCGCGCCAGGGAGGCCGCATGCTGA

Protein sequence : 
MSWLLEPFGYHYMLNAMWVSALVGGVCAFLSCYLMLKGWSLIGDALSHSIVPGVAGAYMLGLPFALGAFLSGGLAAGSML
FLQQRSRLKEDAIIGLIFSSFFGIGLFMVSLNPTSVNIQTIILGNILAIAPEDIIQLAAIGFISMAILLLKWKDLMVTFF
DENHARSIGLNTRGLKLLFFTLLAACTVAALQTVGAFLVICLVVTPGATAWLLTDRFPRLLAIAVAIGSLTSFFGAWLSY
YLDGATGGIIVVAQTLLFLITFIFAPKHGLLASRRRAREAAC

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sitC NP_461784.1 permease Virulence SPI-1 Protein 2e-83 88
sitC NP_457257.1 Iron transport protein, inner membrane component Virulence SPI-1 Protein 2e-83 88
sitC NP_806466.1 iron transporter inner membrane protein Virulence SPI-1 Protein 2e-83 88
sitC AAD41067.1 SitC Virulence centisome 63 pathogenicity island Protein 1e-83 88
sitC YP_217783.1 iron transporter: fur regulated Virulence SPI-1 Protein 2e-83 88
sitD AAD41068.1 SitD Virulence centisome 63 pathogenicity island Protein 5e-35 43
sitD NP_457258.1 Iron transport protein, inner membrane component Virulence SPI-1 Protein 9e-35 43
sitD NP_806467.1 iron transporter inner membrane protein Virulence SPI-1 Protein 9e-35 43
sitD YP_217784.1 iron transporter: fur regulated Virulence SPI-1 Protein 9e-35 43
sitD NP_461785.1 permease Virulence SPI-1 Protein 7e-35 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
afeC YP_002236911.1 iron ABC transporter permease AfeC BAC0351 Protein 8e-84 88
afeC YP_002236911.1 iron ABC transporter permease AfeC BAC0441 Protein 3e-66 70
afeC YP_002236911.1 iron ABC transporter permease AfeC BAC0352 Protein 3e-35 43
afeC YP_002236911.1 iron ABC transporter permease AfeC BAC0442 Protein 2e-30 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
afeC YP_002236911.1 iron ABC transporter permease AfeC VFG0527 Protein 8e-84 88
afeC YP_002236911.1 iron ABC transporter permease AfeC VFG0528 Protein 3e-35 43