Gene Information

Name : afeD (KPK_1041)
Accession : YP_002236910.1
Strain : Klebsiella pneumoniae 342
Genome accession: NC_011283
Putative virulence/resistance : Virulence
Product : iron ABC transporter permease AfeD
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1108
EC number : -
Position : 1058871 - 1059725 bp
Length : 855 bp
Strand : -
Note : identified by similarity to SP:Q56955; match to protein family HMM PF00950

DNA sequence :
ATGCTGAACCTGTTCCTGGCCCCGTTCCAGTTTCCTTTTATGGTCAATGCGATAGCGGTATCGATCATCGTGGCCGTGCC
CTGCGCGCTACTGTCGGTGTTTCTGGTGCTCAAAGGCTGGGCGCTGATGGGCGACGCCATGAGCCACGCGGTCTTTCCGG
GCGTGGTGCTGGCCTACATTATCGGCATCCCCTTCGCCATCGGCGCGTTTATCGCCGGGCTGCTGTGCGCCGTGACGACC
GGTTTTCTCGACGATAACAGCCGACTCAAGCGCGATACCATCATGGGGATTGTCTTCTCCGGCATGTTTGGCGCCGGGCT
GGTGCTGTATGTAGCTATCCAGTCCGATGTTCATCTCGACCATATCCTGTTCGGCGACATGCTGGGGATATCCCTTCGCG
ATATTGGACAAACGGCGGCTATCGCGCTGGTGATTGCGCTGATTATCGGTCTCAAATGGCGCGATTTTTTGCTGCACGCC
TTTGACCCGACGCAGGCCAAAGCCAGCGGCCTGCGCGGCGGACTATTGCACTACGGTCTGCTGTGCATGATCGCCCTGAC
CATCGTCGCGACGCTGCAGTCGGTGGGGATTATCCTGTCGATTTCGCTGCTGATTGCCCCCGGGGCGATCGCGCTCCTGC
TGGTGCGGCGCTTTATCCACGCCCTGCTGCTGGCGGTAGCGGTGGCCATCGGCTGCTCGGCGGGAGGGGTGTGGCTGGCG
TTTTATCTCGACAGCGCGCCGGCGCCGACTATCGTGGTGCTGTTTTCCGCGCTGTTTGTGGTCGCCTTTGTGGCAAGCAC
AATTCGGGATAGTCAGAAACAGAGGGCTTCAGCAACCATCCCCGGTGGCGGCTAA

Protein sequence :
MLNLFLAPFQFPFMVNAIAVSIIVAVPCALLSVFLVLKGWALMGDAMSHAVFPGVVLAYIIGIPFAIGAFIAGLLCAVTT
GFLDDNSRLKRDTIMGIVFSGMFGAGLVLYVAIQSDVHLDHILFGDMLGISLRDIGQTAAIALVIALIIGLKWRDFLLHA
FDPTQAKASGLRGGLLHYGLLCMIALTIVATLQSVGIILSISLLIAPGAIALLLVRRFIHALLLAVAVAIGCSAGGVWLA
FYLDSAPAPTIVVLFSALFVVAFVASTIRDSQKQRASATIPGGG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sitD NP_457258.1 Iron transport protein, inner membrane component Virulence SPI-1 Protein 1e-59 81
sitD NP_806467.1 iron transporter inner membrane protein Virulence SPI-1 Protein 1e-59 81
sitD NP_461785.1 permease Virulence SPI-1 Protein 9e-60 81
sitD YP_217784.1 iron transporter: fur regulated Virulence SPI-1 Protein 9e-60 81
sitD AAD41068.1 SitD Virulence centisome 63 pathogenicity island Protein 7e-60 81
sitC NP_461784.1 permease Virulence SPI-1 Protein 5e-19 42
sitC AAD41067.1 SitC Virulence centisome 63 pathogenicity island Protein 4e-19 42
sitC NP_457257.1 Iron transport protein, inner membrane component Virulence SPI-1 Protein 6e-19 42
sitC NP_806466.1 iron transporter inner membrane protein Virulence SPI-1 Protein 6e-19 42
sitC YP_217783.1 iron transporter: fur regulated Virulence SPI-1 Protein 5e-19 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
afeD YP_002236910.1 iron ABC transporter permease AfeD BAC0352 Protein 4e-60 81
afeD YP_002236910.1 iron ABC transporter permease AfeD BAC0442 Protein 7e-38 55
afeD YP_002236910.1 iron ABC transporter permease AfeD BAC0441 Protein 2e-22 44
afeD YP_002236910.1 iron ABC transporter permease AfeD BAC0351 Protein 2e-19 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
afeD YP_002236910.1 iron ABC transporter permease AfeD VFG0528 Protein 4e-60 81
afeD YP_002236910.1 iron ABC transporter permease AfeD VFG0527 Protein 2e-19 42