Gene Information

Name : metB (SG3320)
Accession : YP_002228125.1
Strain : Salmonella enterica 287/91
Genome accession: NC_011274
Putative virulence/resistance : Unknown
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : -
Position : 3475549 - 3476709 bp
Length : 1161 bp
Strand : -
Note : catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine

DNA sequence :
ATGACGCGTAAACAGGCCACTATCGCAGTGCGTAGCGGATTAAACGATGACGAACAATACGGCTGCGTTGTGCCGCCAAT
CCATCTCTCCAGTACCTATAACTTTACCGGTTTCAATGAGCCGCGCGCGCATGATTATTCCCGCCGCGGTAATCCCACGC
GTGATGTTGTTCAGCGCGCATTAGCGGAACTGGAAGGCGGCGCGGGCGCGGTATTGACGAATACCGGCATGTCGGCGATT
CATCTGGTCACCACCGTTTTCCTCAAGCCGGGCGATCTGCTGGTCGCGCCGCATGATTGCTATGGCGGCAGTTATCGTCT
GTTTGACAGTCTGGCGACACGCGGCTGTTATCGTGTGCGGTTTGTCGATCAGGGCGATGAACGCGCCTTACAGGCGGCGC
TGGAAGAAAAACCGAAGCTGGTACTGGTAGAAAGTCCAAGTAATCCATTGTTACGCGTGGTGGATATTGCGAAAATCTGT
CGGCTGGCGCGCGAGGCGGGCGCAGTGAACGTCGTTGATAACACGTTTTTAAGCCCGGCGCTGCAAAATCCGCTGGCGTT
GGGTGCCGATCTGGTGTTGCATTCATGCACGAAATATCTCAACGGTCATTCGGATGTCGTGGCCGGCGTGGTGATTGCGA
AAGATCCGGAAGTGGTCACTGAACTGGCGTGGTGGGCGAATAATATTGGCGTGACCGGCGGGGCGTTTGATAGCTATCTG
CTGCTGCGCGGTTTGCGAACTCTGGTGCCGCGTATGGAGCTGGCGCAGCGCAACGCGCAGGCGATTGTGAAATATCTGCA
AACCCAGCCGTTGGTGAAAAAACTGTATCACCCGTCGCTGCCGGAAAATCAGGGGCATGAAATTGCCGCGCGCCAGCAAA
AAGGCTTTGGCGCAATGTTGAGTTTTGAACTGGATGGGGATGAGGAGACGCTGCGTCGTTTTCTGGGCGGGCTGTCGCTG
TTTACGCTGGCGGAATCTTTAGGGGGAGTGGAAAGTTTGATCTCTCACGCCGCCACCATGACGCATGCCGGTATGTCGCC
GCAGGCGCGTGCCGCCGCCGGGATCTCCGAAACGCTACTGCGTATCTCCACCGGTATTGAAGATGGCGAAGATTTAATTG
CCGACCTGGAAAATGGCTTCCGGGCTGCAAACAAGGGGTAA

Protein sequence :
MTRKQATIAVRSGLNDDEQYGCVVPPIHLSSTYNFTGFNEPRAHDYSRRGNPTRDVVQRALAELEGGAGAVLTNTGMSAI
HLVTTVFLKPGDLLVAPHDCYGGSYRLFDSLATRGCYRVRFVDQGDERALQAALEEKPKLVLVESPSNPLLRVVDIAKIC
RLAREAGAVNVVDNTFLSPALQNPLALGADLVLHSCTKYLNGHSDVVAGVVIAKDPEVVTELAWWANNIGVTGGAFDSYL
LLRGLRTLVPRMELAQRNAQAIVKYLQTQPLVKKLYHPSLPENQGHEIAARQQKGFGAMLSFELDGDEETLRRFLGGLSL
FTLAESLGGVESLISHAATMTHAGMSPQARAAAGISETLLRISTGIEDGEDLIADLENGFRAANKG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 5e-61 43
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-62 43
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 5e-51 41