Gene Information

Name : guaA (BDU_1142)
Accession : YP_002223545.1
Strain :
Genome accession: NC_011247
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 158404 - 159945 bp
Length : 1542 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
GTGAGTAATAATGCATTAGTTATCTTGGATTTTGGTTCTCAGTATAGTCAACTTATTGCAAGAAAAATTAGAGAGATGGG
TGTATATACAATAATAGTTACATATTCTCTTTCTGCTAAAGAAATTAAGGATATGAATCCTGTAGGGTTAATTTTAAGTG
GCGGTCCTGCTTCTGTATATTTGGATGAAGCACCTGGTGTTGATATTGAGATTTTTGATTTGGGTATTCCTATTTTGGGG
ATATGTTATGGTATGCAATTGATTATTAAGGTATTTGGAGGTGTGATTTCTAAGTGTGATAAGCAGGAATTTGGACATAC
TGAATTATTTATTGATGATAATAAAGCCGATTTATTTTTAGAGCTTCCAAGTAAATTTGAAGTGATGATGAGTCATGGAG
ATAATATAGAAAAAATACCAGAGGGTTTTAAGCAAATTGCTTATACTAAGGTTTGTGTTGGAGCTGTATTTAATTTAGAG
AAAAGAATTTATGGTGTACAATTTCATCCGGAAGTAAGTTGTTGTGATATTGGTAATCAAATATTTATGAATTTTGTTTT
TAAAATTTGTAAAGCACAGACAAATTGGGATTTAAGTAATAGTATAGAAGATTTAGTAAAAGGTATAAGACATGAGGTAG
GTGATAGTAAGGTAATTTTGGGACTCTCTGGAGGAATAGATTCTTTGGTATGTGCTTTGCTGATTAATAAGGCAATAAAG
GATAATTTGATATGTGTATTTGTTGATACTGGCTTTTTAAGGAAGAATGAAGCCAATGAGATATTGGAATTTAATAAGAA
GTATAATTTGAATATAAAACATATTGATTCTTCTTTGTTGTTTTTAACTAATTTAAGGGATGTAGATGATCCTGAAGAGA
AAAGAAAAATTATAGGGAAAACATTTGTAGAAATTTTTGAAAAGGTGGCATTAGAAGAGGATGATATAAAATATTTAGCT
CAAGGAACTATTTATTCAGATGTTATTGAATCTGATGTTAAGAATAATGTTTGCTCTTCAAAAAATATTAAATCACATCA
TAATGTAGGAGGACTTCCCGATAAAATTAACCTAAATTTATTAGAACCGTTAAGGAATCTTTTTAAAGATGAGGTAATTC
AATTGGGAGTGCAATTGGGTCTTGAAGAGGAAGTTCTCTATAGACATCCATTTCCAGGGCCAGGATTGGCAATAAGAATA
ATAGGGGAAATAACAAAAGATAAGATTGATATTTTGCAAGGAGCTGATCATATTTTTATAGAAGAGCTTTTGATAAATAA
TTTATATTATAAAGTAAGACAAGCATTTGTGGTGTTATTGCCTGTAAGAACTGTAGGTGTTATGGGAGATAACAGAACAT
ATGAATATACAGCTGTCATTCGGTGTGTTAATACTCTAGATTTTATGACAGCTAGTTGGGTTGAGTTACCTTATAGTTTT
TTAAGAAAAGTTTCATCACGAATAATTAATGAAATTAGGGGGATAAATAGAGTTTGTTATGATATTTCTTCTAAGCCTCC
AGCGACGATAGAATGGGAATAA

Protein sequence :
MSNNALVILDFGSQYSQLIARKIREMGVYTIIVTYSLSAKEIKDMNPVGLILSGGPASVYLDEAPGVDIEIFDLGIPILG
ICYGMQLIIKVFGGVISKCDKQEFGHTELFIDDNKADLFLELPSKFEVMMSHGDNIEKIPEGFKQIAYTKVCVGAVFNLE
KRIYGVQFHPEVSCCDIGNQIFMNFVFKICKAQTNWDLSNSIEDLVKGIRHEVGDSKVILGLSGGIDSLVCALLINKAIK
DNLICVFVDTGFLRKNEANEILEFNKKYNLNIKHIDSSLLFLTNLRDVDDPEEKRKIIGKTFVEIFEKVALEEDDIKYLA
QGTIYSDVIESDVKNNVCSSKNIKSHHNVGGLPDKINLNLLEPLRNLFKDEVIQLGVQLGLEEEVLYRHPFPGPGLAIRI
IGEITKDKIDILQGADHIFIEELLINNLYYKVRQAFVVLLPVRTVGVMGDNRTYEYTAVIRCVNTLDFMTASWVELPYSF
LRKVSSRIINEIRGINRVCYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-113 48
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 9e-114 48
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-113 48
guaA NP_938969.1 GMP synthase Not tested Not named Protein 9e-107 46