Gene Information

Name : guaA (BRE_1108)
Accession : YP_002223411.1
Strain :
Genome accession: NC_011246
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 118098 - 119639 bp
Length : 1542 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
GTGAGTAATAATGCAGTAGTTATCTTGGATTTTGGTTCTCAGTATAGTCAACTTATTGCAAGAAAAATTAGAGAGATGGG
TGTATATACAATAATAGTTACATATTCTCTTTCTGCTAAAGAAATTAAGGATATGAATCCTGTAGGGTTAATTTTAAGTG
GCGGTCCTGCTTCTGTATATTTGGATGAAGCACCTGGTGTTGATATTGAGATTTTTGATTTGGGTATTCCTATTTTGGGG
ATATGTTATGGTATGCAATTGATTATTAAGGTATTTGAAGGTGTGATTTCTAAGTGTGATAAGCAGGAATTTGGACATAC
TGAATTATTTATTGATGATAATAAAGCCGATTTATTTTTAGAGCTTCCAAGTAAATTTGAAGTGATGATGAGCCATGGAG
ATAATATAGAAAAAATACCAGAGGGTTTTAAGCAAATTGCTTATACTAAGATTTGTGTTGGAGCTGTATTTAATTTAGAG
AAAAGAATTTATGGTGTACAATTTCATCCGGAAGTAAGTTGTTGTGATATTGGTAATCAAATATTTATGAATTTTGTTTT
TAAAATTTGTAAAGCACAGACAAATTGGGATTTAAGTAATAGTATAGAAGATTTAGTAAAAGGTATAAGACATGAGGTAG
GTGATAGTAAGGTAATTTTGGGACTCTCTGGAGGAATAGATTCTTTGGTGTGTGCTTTGCTGATTAATAAGGCAATAAAA
GATAATTTGATATGTGTATTTGTTGATACTGGCTTTTTAAGGAAAAATGAAGCCAATGGGATATTGGAATTTAATAAGAA
GTATAATTTGAATATAAAACATATTGATTCTTCTTTGTTGTTTTTAACTAATTTAAGGGATGTAGATGATCCTGAAGAGA
AGAGAAAAATTATAGGGAAAACATTTGTAGAAATTTTTGAAAAGGTGGCATTAGAAGAGGATGATATAAAATATTTAGCT
CAAGGAACTATTTATTCAGATGTTATTGAATCTGATGTTAAGAATAATGTTTGCTCTTCAACAAATATTAAATCACATCA
TAATGTAGGAGGACTTCCCGATAAAATTAACCTAAATTTATTAGAACCGTTAAGGAATCTTTTTAAAGATGAGGTAATTC
AATTGGGAGTGCAATTGGGTCTTGAAGAGGAAGTTCTCTATAGACATCCATTTCCAGGGCCAGGATTGGCAATAAGAATA
ATAGGGGAAATAACAAAAGATAAGATTGATATTTTGCAAGGAGCTGATCATATTTTTATAGAAGAGCTTTTGATAAATGA
TTTATATTATAAAGTAAGACAAGCATTTGTGGTGTTATTGCCTGTAAGAACTGTAGGTGTTATGGGAGATAACAGAACAT
ATGAATATACAGCTGTCATTAGGTGTGTTAATACTTTAGATTTTATGACAGCTAGTTGGGTTGAGTTACCTTATAGTTTT
TTAAGAAAAGTTTCATCAAGAATAATTAATGAAATTAGGGGGATAAATAGAGTGTGTTATGATATTTCTTCTAAGCCTCC
AGCGACGATAGAATGGGAATAA

Protein sequence :
MSNNAVVILDFGSQYSQLIARKIREMGVYTIIVTYSLSAKEIKDMNPVGLILSGGPASVYLDEAPGVDIEIFDLGIPILG
ICYGMQLIIKVFEGVISKCDKQEFGHTELFIDDNKADLFLELPSKFEVMMSHGDNIEKIPEGFKQIAYTKICVGAVFNLE
KRIYGVQFHPEVSCCDIGNQIFMNFVFKICKAQTNWDLSNSIEDLVKGIRHEVGDSKVILGLSGGIDSLVCALLINKAIK
DNLICVFVDTGFLRKNEANGILEFNKKYNLNIKHIDSSLLFLTNLRDVDDPEEKRKIIGKTFVEIFEKVALEEDDIKYLA
QGTIYSDVIESDVKNNVCSSTNIKSHHNVGGLPDKINLNLLEPLRNLFKDEVIQLGVQLGLEEEVLYRHPFPGPGLAIRI
IGEITKDKIDILQGADHIFIEELLINDLYYKVRQAFVVLLPVRTVGVMGDNRTYEYTAVIRCVNTLDFMTASWVELPYSF
LRKVSSRIINEIRGINRVCYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 6e-113 48
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 8e-113 48
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 8e-113 48
guaA NP_938969.1 GMP synthase Not tested Not named Protein 4e-106 46