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Name : leuS (BRE_252) Accession : YP_002222722.1 Strain : Borrelia recurrentis A1 Genome accession: NC_011244 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : 6.1.1.4 Position : 270831 - 273359 bp Length : 2529 bp Strand : + Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGTCTAAATATGACTTTAAAAAAATAGAAAAAAAATGGCAAAATTATTGGGATAAACACAAAACATATAAAGTAAACGA AGATCCAAATGTTCCAAAAGAAAAAAGAATCTATATTCTTGACATGTTTCCTTATCCTTCAGCTAATGGACTCCATGTCG GACACCCTGAAGGTTATACGGCCACTGACATATTAACAAGATATAAGCTTTTAAATGGATTTAATGTACTTCATCCAATG GGGTTTGATAGTTTTGGATTACCTGCAGAAAATTATGCAATACAAACAGGAAAACATCCTAAAAAAATAACAGAAAAAAA TATTGAAAAATTTAAAGAACAAATTAAAGCATTAGGATTTGCATATGATTGGGACAGAGAAATTAAAACTCATGATGTAA ATTATTATAAATGGACACAATGGATCTTCCTTCAATTATATAAAAAAGGCTTGGCTTACACAAAAGAAATACCTGTCTGG TATTGTCCTGATCTTGGAACAGTGCTTGCAAATGAAGAAGTAATTCAAACACCCGATGGACCTAGATCAGAACGGGGGTT TCATAAAGTAGAAAGAAAACCTTTAAGACAATGGCTACTCAAAATCACCAAATATGCAGAAAGACTTATTAGAGATCTTG AAGAAGTAGATTGGCCTGACTCTGTCAAAGAAATGCAAAAAAATTGGATTGGAAAATCAACAGGAGTTGAAATTGAATTC TTAATAAAGGAAAGTAAAGAAAAAATAAAGGTATTTACAACAAGACCAGATACAATTTTTGGAGTAACATATTTAGTACT TGCCCCAGAACATCCTATGGTAGATAAAATCACGAAAGATGAACTTAAACCTATAATATCAAAATATAAAGACAAAGAAA TCCTTAAAAGCGATCTTGAGAGGACTTCTCTTGAAAAAGATAAAACAGGAATATTTACAGGGGCATATGCTATTAATCCA ATAACTAAAGAGGAAATACCAATTTGGATAGGAAGTTATATACTTGGCACTTATGGAACTGGAGCTGTAATGAGTGTTCC TGCACACGATGAACGAGATTTTGAATTTGCAAAAAAATATAATTTGCCTATCAAACAAGTGGTCTCTCAAACTGGAACTA ATGAAGTATTAATAAAACCATTTACCGAAAATGGTATTTCAATTAACACACCTACAGAATTTAACAATCTCAAAACTATA GAAGTAAAAACAAAAGTAATAAAATGGCTTATAGAAAATAAAATGGGCCAAGAAAAAGTTAATTATAAACTTAGAGACTG GATTTTCTCAAGACAGAGATACTGGGGAGAACCTATTCCTATTTTATTTGATGACAACCTAAATGAAATACCATTAAACG ACGATGAACTACCCTTAACACTTCCAGATATAGAAAATTATAAACCATCTGGCACAGGAGAATCGCCTCTCTCAAAAATT AAAGACTGGGTAAATGTTAAACGTAACGGGAAAATATATAAAAGAGAAACAAACACAATGCCCCAATGGGCAGGCTCATG TTGGTACTATATACGCTACCTTGATCCTCATAACGAAAAAGAATTTGCAAATAAAGAAAAAATCAATTATTGGATGCCAG TTGATCTTTATATTGGAGGCGCTGAACATTCAGTGCTACACTTATTATACGCAAGATTTTGGCATAAAGTTCTTTATGAT TTAGGATATGTTAATATAAAAGAACCCTTTAGAAAACTTATAAATCAAGGAATGATAACATCATTTGCATATCAAGACGA AAATGGTATTTTAATTCCCAATGATGAAGTGGAAAAAAAAGACAACAAATTTTTTTCAAAAAAAAATAATAAAGAACTAA AACAAATAATAGCAAAAATGTCCAAATCACTTAAAAATATAATAAATCCGGATGACATCATTAAAGAATACGGTGCAGAT TCAATGAGAATATATGAAATGTTTATGGGACCTTTAACCGACTCAAAACCATGGAATACACAAGGACTCATTGGAATTTT TAGATTTTTAAACAAAATATGGCTCATCAAGAACAAAGAACTTACTAACGAAACACCTCCAAAAGAAATAATATCGGAAC TGCATAAAACAATAAAAAAAGTTACAGAAGATATAGAAACTTTAAATTTTAATACCGCAATTTCAACATTAATGATATTC ATAAACGAACTTCTAAAACATGAAAAAAATTACTTAAAAATATTTAGACCTATAAGCATTATCTTATCACCATTTGCACC ACATTTAGGAGAAGAATTATGGGAATTCATGGGCGAACAATCCAGTATATTTAAAAATGCAAAATGGCCAAAATATGATT TAAATTCAATTATTGATGATACAAGAGAAATTGTACTACAGGTTAATGGTAAAACAAAAGACAAAATTATGATAAAAAAA GACACTGATGAGAAAACTCTTAAAAAGATTGCTTTTAATAATCAAAAAATTATACAAAATATAAACAATAAACAAATAAT AAAAATTATTACAGTTAAAGACAAACTTGTAAATATAGTAGCAAAATAA Protein sequence : MSKYDFKKIEKKWQNYWDKHKTYKVNEDPNVPKEKRIYILDMFPYPSANGLHVGHPEGYTATDILTRYKLLNGFNVLHPM GFDSFGLPAENYAIQTGKHPKKITEKNIEKFKEQIKALGFAYDWDREIKTHDVNYYKWTQWIFLQLYKKGLAYTKEIPVW YCPDLGTVLANEEVIQTPDGPRSERGFHKVERKPLRQWLLKITKYAERLIRDLEEVDWPDSVKEMQKNWIGKSTGVEIEF LIKESKEKIKVFTTRPDTIFGVTYLVLAPEHPMVDKITKDELKPIISKYKDKEILKSDLERTSLEKDKTGIFTGAYAINP ITKEEIPIWIGSYILGTYGTGAVMSVPAHDERDFEFAKKYNLPIKQVVSQTGTNEVLIKPFTENGISINTPTEFNNLKTI EVKTKVIKWLIENKMGQEKVNYKLRDWIFSRQRYWGEPIPILFDDNLNEIPLNDDELPLTLPDIENYKPSGTGESPLSKI KDWVNVKRNGKIYKRETNTMPQWAGSCWYYIRYLDPHNEKEFANKEKINYWMPVDLYIGGAEHSVLHLLYARFWHKVLYD LGYVNIKEPFRKLINQGMITSFAYQDENGILIPNDEVEKKDNKFFSKKNNKELKQIIAKMSKSLKNIINPDDIIKEYGAD SMRIYEMFMGPLTDSKPWNTQGLIGIFRFLNKIWLIKNKELTNETPPKEIISELHKTIKKVTEDIETLNFNTAISTLMIF INELLKHEKNYLKIFRPISIILSPFAPHLGEELWEFMGEQSSIFKNAKWPKYDLNSIIDDTREIVLQVNGKTKDKIMIKK DTDEKTLKKIAFNNQKIIQNINNKQIIKIITVKDKLVNIVAK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 0.0 | 54 |
