Gene Information

Name : leuS (BDU_253)
Accession : YP_002221911.1
Strain : Borrelia duttonii Ly
Genome accession: NC_011229
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 269880 - 272408 bp
Length : 2529 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGTCTAAATATGACTTTAAAAAAATAGAAAAAAAATGGCAAAATTATTGGGATAAACACAAAACATATAAAGTAAACGA
AGATCCAAATGTTCCAAAAGAAAAAAGAATCTATATTCTTGACATGTTTCCTTATCCTTCAGCTAATGGACTCCATGTCG
GACACCCTGAAGGTTATACGGCCACTGACATATTAACAAGATATAAGCTTTTAAATGGATTTAATGTACTTCATCCAATG
GGGTTTGATAGTTTTGGATTACCTGCAGAAAATTATGCAATACAAACAGGAAAACATCCTAAAAAAATAACAGAAAAAAA
TATTGAAAAATTTAAAGAACAAATTAAAGCATTAGGATTTGCATATGATTGGGACAGAGAAATTAAAACTCATGATGTAA
ATTATTATAAATGGACACAATGGATCTTCCTTCAATTATATAAAAAAGGCTTGGCTTACACAAAAGAAATACCTGTCTGG
TATTGTCCTGATCTTGGAACAGTGCTTGCAAATGAAGAAGTAATTCAAACACCCGATGGACCTAGATCAGAACGGGGGTT
TCATAAAGTAGAAAGAAAACCTTTAAGACAATGGCTACTCAAAATCACCAAATATGCAGAAAGACTTATTAGAGATCTTG
AAGAAGTAGATTGGCCTGACTCTGTCAAAGAAATGCAAAAAAATTGGATTGGAAAATCAACAGGAGTTGAAATTGAATTC
TTAATAAAGGAAAGTAAAGAAAAAATAAAGGTATTTACAACAAGACCAGATACAATTTTTGGAGTAACATATTTAGTACT
TGCACCAGAACATCCTATGGTAGATAAAATCACGAAAGATGAACTTAAACCTATAATATCAAAATATAAAGACAAAGAAA
TCCTTAAAAGCGATCTTGAGAGGACTTCTCTTGAAAAAGATAAAACAGGAATATTTACAGGGGCATATGCTATTAATCCA
ATAACTAAAGAGGAAATACCAATTTGGATAGGAAGTTATATACTTGGCACTTATGGAACTGGAGCTGTAATGAGTGTTCC
TGCACACGATGAACGAGATTTTGAATTTGCAAAAAAATATAATTTGCCTATCAAACAAGTGGTCTCTCAAACTGGAACTA
ATGAAGTATTAATAAAACCATTTACCGAAAATGGTATTTCAATTAACACACCTACAGAATTTAACAATCTCAAAACTATA
GAAGTAAAAACAAAAGTAATAAAATGGCTTATAGAAAATAAAATGGGCCAAGAAAAAGTTAATTATAAACTTAGAGACTG
GATTTTCTCAAGACAGAGATACTGGGGAGAACCTATTCCTATTTTATTTGATGACAACCTAAATGAAATACCATTAAACG
ACGATGAACTACCCTTAACACTTCCAGACATAGAAAATTATAAACCATCTGGCACAGGAGAATCGCCTCTCTCAAAAATT
AAAGACTGGGTAAATGTTAAACGTAACGGGAAAATATATAAAAGAGAAACAAACACAATGCCCCAATGGGCAGGCTCATG
TTGGTACTATATACGCTACCTTGATCCTCATAACAAAAAAGAATTTGCAAATAAAGAAAAAATCAATTATTGGATGCCAG
TTGATCTTTATATTGGAGGCGCTGAACATTCAGTGCTACACTTATTATACGCAAGATTTTGGCATAAAGTTCTTTATGAT
TTAGGATATGTTAATACAAAAGAACCCTTTAGAAAACTTATAAATCAAGGAATGATAACATCATTTGCATATCAAGACGA
AAATGGTATTTTAATTCCCAATGATGAAGTGGAAAAAAAAGACAACAAATTTTTTTCAAAAAAAAATAATAAAGAACTAA
AACAAATAATAGCAAAAATGTCCAAATCACTTAAAAACATAATAAATCCGGATGACATCATTAAAGAATACGGTGCAGAT
TCAATGAGAATATATGAAATGTTTATGGGACCTTTAACCGACTCAAAACCATGGAATACACAAGGACTCATTGGAATTTT
TAGATTTTTAAACAAAATATGGCTCATCAAGAACAAAGAACTTACTAACGAAACACCTCCAAAAGAAATAATATCGGAAC
TGCATAAAACAATAAAAAAAGTTACAGAAGATATAGAAACTTTAAATTTTAATACCGCAATTTCAACATTAATGATATTC
ATAAACGAACTTCTAAAACATGAAAAAAATTACTTAAAAATATTTAGACCTATAAGCATTATCTTATCACCATTTGCACC
ACATTTAGGAGAAGAATTATGGGAATTCATGGGCGAACAATCCAGTATATTTAAAAATGCAAAATGGCCAAAATATGATT
TAAATTCAATTATTGATGATACAAGAGAAATTGTACTACAGGTTAATGGTAAAACAAAAGACAAAATTATGATAAAAAAA
GACACTGATGAGGAAACTCTTAAAAAGATTGCTTTTAATAATCAAAAAATTATACAAAATATAAACAATAAACAAATAAT
AAAAATTATTACAGTTAAAGACAAACTTGTAAATATAGTAGCAAAATAA

Protein sequence :
MSKYDFKKIEKKWQNYWDKHKTYKVNEDPNVPKEKRIYILDMFPYPSANGLHVGHPEGYTATDILTRYKLLNGFNVLHPM
GFDSFGLPAENYAIQTGKHPKKITEKNIEKFKEQIKALGFAYDWDREIKTHDVNYYKWTQWIFLQLYKKGLAYTKEIPVW
YCPDLGTVLANEEVIQTPDGPRSERGFHKVERKPLRQWLLKITKYAERLIRDLEEVDWPDSVKEMQKNWIGKSTGVEIEF
LIKESKEKIKVFTTRPDTIFGVTYLVLAPEHPMVDKITKDELKPIISKYKDKEILKSDLERTSLEKDKTGIFTGAYAINP
ITKEEIPIWIGSYILGTYGTGAVMSVPAHDERDFEFAKKYNLPIKQVVSQTGTNEVLIKPFTENGISINTPTEFNNLKTI
EVKTKVIKWLIENKMGQEKVNYKLRDWIFSRQRYWGEPIPILFDDNLNEIPLNDDELPLTLPDIENYKPSGTGESPLSKI
KDWVNVKRNGKIYKRETNTMPQWAGSCWYYIRYLDPHNKKEFANKEKINYWMPVDLYIGGAEHSVLHLLYARFWHKVLYD
LGYVNTKEPFRKLINQGMITSFAYQDENGILIPNDEVEKKDNKFFSKKNNKELKQIIAKMSKSLKNIINPDDIIKEYGAD
SMRIYEMFMGPLTDSKPWNTQGLIGIFRFLNKIWLIKNKELTNETPPKEIISELHKTIKKVTEDIETLNFNTAISTLMIF
INELLKHEKNYLKIFRPISIILSPFAPHLGEELWEFMGEQSSIFKNAKWPKYDLNSIIDDTREIVLQVNGKTKDKIMIKK
DTDEETLKKIAFNNQKIIQNINNKQIIKIITVKDKLVNIVAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 54