Gene Information

Name : Lferr_0364 (Lferr_0364)
Accession : YP_002218825.1
Strain : Acidithiobacillus ferrooxidans ATCC 53993
Genome accession: NC_011206
Putative virulence/resistance : Virulence
Product : two component sigma-54 specific Fis family transcriptional regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG2204
EC number : -
Position : 342399 - 343754 bp
Length : 1356 bp
Strand : +
Note : PFAM: response regulator receiver; sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; SMART: AAA ATPase; KEGG: pmy:Pmen_0965 two component, sigma54 specific, transcriptional regulator, fis family

DNA sequence :
ATGGCTGACTATTCCGTATTGCCGCCCGCCCTGATCGTAGATGACGAGCCGGGCATCGTCGAACTGCTGGGCATTACGCT
GCAGGGTATGGGGATCGCTGTCACGGGCGCATATTCCCTTGCAGAAGCCCGCGCCCGCCTCGCCGAAGGCGCCCCTTCTT
TATGTCTGAGCGATCTGCGTTTGCCCGACGGTTCCGGTCTTGATCTGGTCCGCCGTTTGCGCGAGTTGTATCCACAAGTG
CCGGTCGCCGTGATTACGGCCTATTCTTCCGCCGATGGTGCCGTCGAAGCGATGCAGGCAGGGGCCTTCGATTACATGGC
CAAGCCCATCGAACTGGCGCGTCTGCGGCGATTGATATCCCAGGCCGTTGATCTCAGCCGCCTGTCCCCGGCGGGCCTGG
GCGGCACGCAACGACTGGTCGGCGATGCTCCGGTCATGCAGCGGTTGCGCGACGATATCCGCCGAGTAGCGCGGAGTAAC
GCGCCGGTACACATCACCGGTGAGTCCGGTACGGGCAAGGAACTGGCCGCACGCGCCATTCACGCCTCGGGACCCCGTCA
CGACAAGCCCTTCGTGGCCGTCAACTGCGGCGCCATTCCCGAGGGATTGGTGGAGAGTGAACTGTTCGGTGCCGAAAAGG
GGGCTTATTCCGGTGCCGTACAGCGTCGCGAAGGACTCTTTGCGGCGGCCAACGGGGGCACTATTTTTCTGGATGAGATC
GGCGATCTGCCGATGATGATGCAGGTCAAGCTGCTGCGGGCCATTCAGGAACGGGCCATTCGCCCCCTGGGCGCGGCGCG
GGAAATCTCCCTGGACCTGCGCTTCATTTCCGCCACCCACCGTGACCTGCAGGAAATGGTTGCGGCCGGAAAGTTTCGTC
AGGATCTCCGGTATCGTCTGGATGTGGTAAGACTCCATATGCCGGCCCTGCGGGAACATCCGGAAGACATCCCGCAACTG
GCAGAGGTGATTCTGCAACGTATCGGCGTGGCACCGCAGGATATTCCAGCGCTGCTGTCCCCAGGCACTTTGGAGCGGCT
GGGTAGTTACGCCTTCCCCGGCAACGTTCGCGAGTTGGAAAACTTTCTGGAGCGGAGCCTTGCCCTCAAGCAGGAAGGGA
TGCTGCTCGACGAAGGGATGTCCTCCCCCGCCGGCCCGGTGTCAAAAAGCAACGGGCCGGCGTTGGCACCGGTAATCGCC
GTACCGGCCGCTTTTGACGCGGCGGAGGCCGCATTGCTGCGGCAGGTGCTCGATCAGGCCGAAGGGGATCGGCGTCATGC
CGCCGTTCTGCTGGGGATCAGTCTGCAGTCGCTGGATCTGCGGCTGCACCGATTATTCCCGGAGGGTGACGCATGA

Protein sequence :
MADYSVLPPALIVDDEPGIVELLGITLQGMGIAVTGAYSLAEARARLAEGAPSLCLSDLRLPDGSGLDLVRRLRELYPQV
PVAVITAYSSADGAVEAMQAGAFDYMAKPIELARLRRLISQAVDLSRLSPAGLGGTQRLVGDAPVMQRLRDDIRRVARSN
APVHITGESGTGKELAARAIHASGPRHDKPFVAVNCGAIPEGLVESELFGAEKGAYSGAVQRREGLFAAANGGTIFLDEI
GDLPMMMQVKLLRAIQERAIRPLGAAREISLDLRFISATHRDLQEMVAAGKFRQDLRYRLDVVRLHMPALREHPEDIPQL
AEVILQRIGVAPQDIPALLSPGTLERLGSYAFPGNVRELENFLERSLALKQEGMLLDEGMSSPAGPVSKSNGPALAPVIA
VPAAFDAAEAALLRQVLDQAEGDRRHAAVLLGISLQSLDLRLHRLFPEGDA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00300 YP_008207765.1 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Not tested AbaR25 Protein 4e-75 45
BJAB0868_00304 YP_008211630.1 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Not tested AbaR26 Protein 4e-75 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Lferr_0364 YP_002218825.1 two component sigma-54 specific Fis family transcriptional regulator BAC0467 Protein 1e-72 47
Lferr_0364 YP_002218825.1 two component sigma-54 specific Fis family transcriptional regulator BAC0089 Protein 7e-67 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Lferr_0364 YP_002218825.1 two component sigma-54 specific Fis family transcriptional regulator VFG1214 Protein 3e-95 50
Lferr_0364 YP_002218825.1 two component sigma-54 specific Fis family transcriptional regulator VFG0116 Protein 7e-55 42