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Name : Lferr_0283 (Lferr_0283) Accession : YP_002218744.1 Strain : Acidithiobacillus ferrooxidans ATCC 53993 Genome accession: NC_011206 Putative virulence/resistance : Unknown Product : DNA topoisomerase III Function : - COG functional category : L : Replication, recombination and repair COG ID : COG0550 EC number : 5.99.1.2 Position : 266349 - 268403 bp Length : 2055 bp Strand : - Note : KEGG: eba:p2B17 TraE protein (DNA topoisomerase); TIGRFAM: DNA topoisomerase III; PFAM: TOPRIM domain protein; DNA topoisomerase type IA central domain protein; SMART: DNA topoisomerase I ATP-binding; DNA topoisomerase I DNA-binding; Toprim sub domain pro DNA sequence : ATGAAACTGTACATCGCCGAGAAGCCCAGCCTGGGCAAAGGGATCGCCGAGTATTTGCCCGGATCGAAGAGCAAAGGGAA CGGCTTCATCCAGTGCGGAGTGGATACCGCCGTGACCTGGTGTTTCGGCCATATATTCGAGCAGGAAGAGCCGGACTTCT ACACGCCTGATGATGTTCCCACCACGCCAAAGGGCAAGAAGAAATGGCGCTTTGAGGAACTGCCCATTTTTCCTGAGCAA TGGAAGAAGCGGGCAAAAGATGACGCCAAGGCCCAGATCAAGGTGATCCGGGACCTGCTCAAGAAAGCGTCGTCTGTCGT CAACGCAGGAGACCCGGACCGAGAGGGCCAGCTGCTGGTGGATGAGGTACTGGAAGAGCTCCGCTGGAAAGGGCCTACGC AACGCATTTGGCTGGCCGCCCTCGATGAGCAGTCCGTGCGCAAGGCGCTGGCCAGTCTGAAGGACAACCGGGACTATCAG AATCTCAGCCATTCTGCCGAGGCCCGCGCCCGCGCGGACTGGCTCATGGGCATGAATCTCACCCGCGCATTCACGCTGCG CAACAGCGGCGCCGGAGTCGTCTCCGTGGGTAGGGTGCAGACGCCAACGCTGGCTCTGGTCGTGGCCCGTGACGAGAAGA TCGAGCACTTCAATCCGAAGGACTACTACGTTCCGCGCATCAACGCGGGCTTCTGGGCCGCCTGGGAGTTGCGGGAGGAT TTCGAGGGTGTCGATGCCGAAGGCTACCTCACCGACCGGAAAGCTGCTGACCGGCTGGCATCCCGGGCCAAGGCGGAAGG CAAGGCGACGGTGAAGGACTTCACCAGCGCCGAAAAGCAGCAGCAGGCCCCATTAGGCTTCTCCCTTGCGGAGTTGCAAA AGGTCTGCTCAGCCAAGCTCGGCATGTCGGCACAAAATGTCCTTGATGCGGCCCAAGCGCTGTACGAGGAACACAAGGCG GCGACCTATCCGCGGACCGATTGCCGCTATCTACCGGAAGAACAGCATGGGGATGCCGGACAGATACTGTCCGGCCTGGC GAAAGCTGGATTTGCGGATCTGGTGAAAGCCGCCGATTCCAACCGGAAGTCGGCCATCTGGAATACGGGCAAAGTGACGG CGCACCACGCCATCATTCCGACCGGCTCCATGCAGGGCTCCATGAGCCCGGCAGTGGCCAAGGTCTACGAGATCATCGTC CGCTCCTATCTCGCGCAGTTCTATCCGCCCTATGTGTACCGGGCGATCAAGGCCCTACTGACTTGCACCGGCGAGGACTG GAAGGCGACTGCCAACATCCCGGTATCCGCAGGCTGGAAAGCCGTGTATGGGATGACCGATGACGATAATGATGACACCC CCGCCCAGTCGATCCCGCCGCTCAAAAAGGGACAGAGCCTGACGGTTCAGGATGCGGACGTGCAGGCAAGGCAGACCAAG CCGCCGGCACGATTTACGGATGGATTGCTCATTGAAGCCATGAGCAACATCCACAAGGTGGTTGAGGACGAGGCCGCCAA GGCCAAGCTCAAGGAAACCTCTGGCCTAGGCACGGAGGCCACCAGGGCCAGCATCATCGAAACACTGCTAACCCGGGGAT TCCTGGAGCGCAAAGGCAAGCAGATTCTCTCCACGCAGGCCGGGCGGGCGCTGGTTCACGCGCTACCCAAAGACCTGACC GATCCCGTCCTGACAGCCCGCTGGGAGGATGCTTTGTCATCCGTTTCCGAAGGCCGCGTGACGCTACAGCAGTTTGAGGA AGCGCAGCGTAAATTTGTTGTCCGCATGATCGAGGCGGCCAAGGCGACGACAGTTGCTGTCGGCCAGGCACGGCCATCTT CCGGCGCTGGTCGTGGCAAGTCGTCTACCGGAAAAACGCGGGGCGGCGGACAAAAGGCTGGCCCAGCCTGCCCGGACTGC AAGAAGCTGACCATCACCCTGAAGACGAAGAAGGGAAGTGCCTTCTTCAAGTGCGAGGGCTGCCAGTCCTGCTGGTGGCC GGACAAGCAGGAACCCAAGAAGCTCGGAACGAAGTGGGGTGAGAAAAAAACATGA Protein sequence : MKLYIAEKPSLGKGIAEYLPGSKSKGNGFIQCGVDTAVTWCFGHIFEQEEPDFYTPDDVPTTPKGKKKWRFEELPIFPEQ WKKRAKDDAKAQIKVIRDLLKKASSVVNAGDPDREGQLLVDEVLEELRWKGPTQRIWLAALDEQSVRKALASLKDNRDYQ NLSHSAEARARADWLMGMNLTRAFTLRNSGAGVVSVGRVQTPTLALVVARDEKIEHFNPKDYYVPRINAGFWAAWELRED FEGVDAEGYLTDRKAADRLASRAKAEGKATVKDFTSAEKQQQAPLGFSLAELQKVCSAKLGMSAQNVLDAAQALYEEHKA ATYPRTDCRYLPEEQHGDAGQILSGLAKAGFADLVKAADSNRKSAIWNTGKVTAHHAIIPTGSMQGSMSPAVAKVYEIIV RSYLAQFYPPYVYRAIKALLTCTGEDWKATANIPVSAGWKAVYGMTDDDNDDTPAQSIPPLKKGQSLTVQDADVQARQTK PPARFTDGLLIEAMSNIHKVVEDEAAKAKLKETSGLGTEATRASIIETLLTRGFLERKGKQILSTQAGRALVHALPKDLT DPVLTARWEDALSSVSEGRVTLQQFEEAQRKFVVRMIEAAKATTVAVGQARPSSGAGRGKSSTGKTRGGGQKAGPACPDC KKLTITLKTKKGSAFFKCEGCQSCWWPDKQEPKKLGTKWGEKKT |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| topB | NP_458624.1 | topoisomerase B | Not tested | SPI-7 | Protein | 8e-105 | 42 |
| topB | NP_807836.1 | DNA topoisomerase III | Not tested | SPI-7 | Protein | 8e-105 | 42 |
| topB | AAF14809.1 | topoisomerase B | Not tested | SPI-7 | Protein | 6e-105 | 42 |
| topB | AAN62317.1 | putative DNA topoisomerase III | Not tested | PAGI-3(SG) | Protein | 8e-104 | 41 |
| pph56 | CAI36097.1 | Topoisomerase IA | Not tested | PPHGI-1 | Protein | 2e-102 | 41 |
