Gene Information

Name : Lferr_0283 (Lferr_0283)
Accession : YP_002218744.1
Strain : Acidithiobacillus ferrooxidans ATCC 53993
Genome accession: NC_011206
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : 5.99.1.2
Position : 266349 - 268403 bp
Length : 2055 bp
Strand : -
Note : KEGG: eba:p2B17 TraE protein (DNA topoisomerase); TIGRFAM: DNA topoisomerase III; PFAM: TOPRIM domain protein; DNA topoisomerase type IA central domain protein; SMART: DNA topoisomerase I ATP-binding; DNA topoisomerase I DNA-binding; Toprim sub domain pro

DNA sequence :
ATGAAACTGTACATCGCCGAGAAGCCCAGCCTGGGCAAAGGGATCGCCGAGTATTTGCCCGGATCGAAGAGCAAAGGGAA
CGGCTTCATCCAGTGCGGAGTGGATACCGCCGTGACCTGGTGTTTCGGCCATATATTCGAGCAGGAAGAGCCGGACTTCT
ACACGCCTGATGATGTTCCCACCACGCCAAAGGGCAAGAAGAAATGGCGCTTTGAGGAACTGCCCATTTTTCCTGAGCAA
TGGAAGAAGCGGGCAAAAGATGACGCCAAGGCCCAGATCAAGGTGATCCGGGACCTGCTCAAGAAAGCGTCGTCTGTCGT
CAACGCAGGAGACCCGGACCGAGAGGGCCAGCTGCTGGTGGATGAGGTACTGGAAGAGCTCCGCTGGAAAGGGCCTACGC
AACGCATTTGGCTGGCCGCCCTCGATGAGCAGTCCGTGCGCAAGGCGCTGGCCAGTCTGAAGGACAACCGGGACTATCAG
AATCTCAGCCATTCTGCCGAGGCCCGCGCCCGCGCGGACTGGCTCATGGGCATGAATCTCACCCGCGCATTCACGCTGCG
CAACAGCGGCGCCGGAGTCGTCTCCGTGGGTAGGGTGCAGACGCCAACGCTGGCTCTGGTCGTGGCCCGTGACGAGAAGA
TCGAGCACTTCAATCCGAAGGACTACTACGTTCCGCGCATCAACGCGGGCTTCTGGGCCGCCTGGGAGTTGCGGGAGGAT
TTCGAGGGTGTCGATGCCGAAGGCTACCTCACCGACCGGAAAGCTGCTGACCGGCTGGCATCCCGGGCCAAGGCGGAAGG
CAAGGCGACGGTGAAGGACTTCACCAGCGCCGAAAAGCAGCAGCAGGCCCCATTAGGCTTCTCCCTTGCGGAGTTGCAAA
AGGTCTGCTCAGCCAAGCTCGGCATGTCGGCACAAAATGTCCTTGATGCGGCCCAAGCGCTGTACGAGGAACACAAGGCG
GCGACCTATCCGCGGACCGATTGCCGCTATCTACCGGAAGAACAGCATGGGGATGCCGGACAGATACTGTCCGGCCTGGC
GAAAGCTGGATTTGCGGATCTGGTGAAAGCCGCCGATTCCAACCGGAAGTCGGCCATCTGGAATACGGGCAAAGTGACGG
CGCACCACGCCATCATTCCGACCGGCTCCATGCAGGGCTCCATGAGCCCGGCAGTGGCCAAGGTCTACGAGATCATCGTC
CGCTCCTATCTCGCGCAGTTCTATCCGCCCTATGTGTACCGGGCGATCAAGGCCCTACTGACTTGCACCGGCGAGGACTG
GAAGGCGACTGCCAACATCCCGGTATCCGCAGGCTGGAAAGCCGTGTATGGGATGACCGATGACGATAATGATGACACCC
CCGCCCAGTCGATCCCGCCGCTCAAAAAGGGACAGAGCCTGACGGTTCAGGATGCGGACGTGCAGGCAAGGCAGACCAAG
CCGCCGGCACGATTTACGGATGGATTGCTCATTGAAGCCATGAGCAACATCCACAAGGTGGTTGAGGACGAGGCCGCCAA
GGCCAAGCTCAAGGAAACCTCTGGCCTAGGCACGGAGGCCACCAGGGCCAGCATCATCGAAACACTGCTAACCCGGGGAT
TCCTGGAGCGCAAAGGCAAGCAGATTCTCTCCACGCAGGCCGGGCGGGCGCTGGTTCACGCGCTACCCAAAGACCTGACC
GATCCCGTCCTGACAGCCCGCTGGGAGGATGCTTTGTCATCCGTTTCCGAAGGCCGCGTGACGCTACAGCAGTTTGAGGA
AGCGCAGCGTAAATTTGTTGTCCGCATGATCGAGGCGGCCAAGGCGACGACAGTTGCTGTCGGCCAGGCACGGCCATCTT
CCGGCGCTGGTCGTGGCAAGTCGTCTACCGGAAAAACGCGGGGCGGCGGACAAAAGGCTGGCCCAGCCTGCCCGGACTGC
AAGAAGCTGACCATCACCCTGAAGACGAAGAAGGGAAGTGCCTTCTTCAAGTGCGAGGGCTGCCAGTCCTGCTGGTGGCC
GGACAAGCAGGAACCCAAGAAGCTCGGAACGAAGTGGGGTGAGAAAAAAACATGA

Protein sequence :
MKLYIAEKPSLGKGIAEYLPGSKSKGNGFIQCGVDTAVTWCFGHIFEQEEPDFYTPDDVPTTPKGKKKWRFEELPIFPEQ
WKKRAKDDAKAQIKVIRDLLKKASSVVNAGDPDREGQLLVDEVLEELRWKGPTQRIWLAALDEQSVRKALASLKDNRDYQ
NLSHSAEARARADWLMGMNLTRAFTLRNSGAGVVSVGRVQTPTLALVVARDEKIEHFNPKDYYVPRINAGFWAAWELRED
FEGVDAEGYLTDRKAADRLASRAKAEGKATVKDFTSAEKQQQAPLGFSLAELQKVCSAKLGMSAQNVLDAAQALYEEHKA
ATYPRTDCRYLPEEQHGDAGQILSGLAKAGFADLVKAADSNRKSAIWNTGKVTAHHAIIPTGSMQGSMSPAVAKVYEIIV
RSYLAQFYPPYVYRAIKALLTCTGEDWKATANIPVSAGWKAVYGMTDDDNDDTPAQSIPPLKKGQSLTVQDADVQARQTK
PPARFTDGLLIEAMSNIHKVVEDEAAKAKLKETSGLGTEATRASIIETLLTRGFLERKGKQILSTQAGRALVHALPKDLT
DPVLTARWEDALSSVSEGRVTLQQFEEAQRKFVVRMIEAAKATTVAVGQARPSSGAGRGKSSTGKTRGGGQKAGPACPDC
KKLTITLKTKKGSAFFKCEGCQSCWWPDKQEPKKLGTKWGEKKT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 6e-105 42
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 8e-105 42
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 8e-105 42
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 8e-104 41
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 2e-102 41