Gene Information

Name : Lferr_2757 (Lferr_2757)
Accession : YP_002221155.1
Strain : Acidithiobacillus ferrooxidans ATCC 53993
Genome accession: NC_011206
Putative virulence/resistance : Resistance
Product : D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding subunit
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1052
EC number : -
Position : 2742201 - 2743196 bp
Length : 996 bp
Strand : -
Note : PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: rca:Rcas_0709 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding

DNA sequence :
ATGCGTTGTCTGGTGACCAGTGCTCGCCCTTACGATGAACAATTCCTCAGCGCCGCCAACCATGGACGCCACGAATTGGT
ATTTGTTGAAACCGCACTGAGCGCGGATACGGCTTTTATTGCCCAGGGATACCCTGCCATTTGCCCCTTCGTGGATGACA
CGCTGGACGCAAAAACACTGGAAACCATAGCGCGCTTGGGGACTAAACTACTGGTCTTGCGCAGCACCGGGTTCAATCAT
GTGGACATGCCTGCGGCCGAGAAGTACGGCATCACCGTCATGCGGGTACGCGATTATTCCCCTTATGCGGTGGCTGAATA
TGCCGTCGGCCTGATGTTGACCCTGAACCGACACCTGCATAAAGCCTATAACCGGGTGCGTGACGGTAATTTTCTCCTCG
ACGGCTTGCTGGGTTTTGACATGCATGGCAAAACCGTAGGCATTATCGGCACTGGAAAAATTGGCCAGGCACTCGCCCGG
ATTCTGCATGGTATGGGCTGCCACTTGTTGGGCTACGACACAGTCGCCAATCCCGCGTGCCTGGAACTCGGCGTTGCATA
TGTACCGCTGGAAGAATTGCTCGTCAAAAGCCAAATCGTCAGCCTCCATGTGCCGCTGCTCCCGGAAACCCGGCATCTGA
TGAATGCGGAACGGTTCGCCTTGATGCCGGACGGTGCCATGCTGATCAATACCAGCCGTGGTCCGCTCATCGACACCACG
GCACTCATTGCGGCACTGAAAAGCCGCCATCTGGGTGCTGTGGGTCTGGATGTCTATGAAGAAGAGGCAGAATTATATTT
TAAGGATCATTGCGATGACATTATCTGCGATGACAGCTTCGAACGGCTGCTCACTTTTCCCAATGTCATCATCACGGGCC
ATCAGGCCTTTTTTACCAGTGAGGCACTGACCACCATTGCCAGGACCACGATCCAGAACCTGGATGACTACAGCGATGGA
AAGGATAATCCCAATTGCGTTCGCAGCAAGGGATGA

Protein sequence :
MRCLVTSARPYDEQFLSAANHGRHELVFVETALSADTAFIAQGYPAICPFVDDTLDAKTLETIARLGTKLLVLRSTGFNH
VDMPAAEKYGITVMRVRDYSPYAVAEYAVGLMLTLNRHLHKAYNRVRDGNFLLDGLLGFDMHGKTVGIIGTGKIGQALAR
ILHGMGCHLLGYDTVANPACLELGVAYVPLEELLVKSQIVSLHVPLLPETRHLMNAERFALMPDGAMLINTSRGPLIDTT
ALIAALKSRHLGAVGLDVYEEEAELYFKDHCDDIICDDSFERLLTFPNVIITGHQAFFTSEALTTIARTTIQNLDDYSDG
KDNPNCVRSKG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
EF2295 NP_815952.1 D-specific alpha-keto acid dehydrogenase Not tested Not named Protein 3e-33 42
vanHB YP_008394258.1 VanH protein, D-specific alpha-keto acid dehydrogenase Not tested Not named Protein 8e-34 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Lferr_2757 YP_002221155.1 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding subunit AF310956.2.orf4.gene Protein 4e-34 42
Lferr_2757 YP_002221155.1 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding subunit U35369.1.gene5.p01 Protein 2e-33 42
Lferr_2757 YP_002221155.1 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding subunit NC_014475.1.orf2.gen Protein 2e-30 42
Lferr_2757 YP_002221155.1 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding subunit NC_005054.2598279.p0 Protein 2e-30 42