Gene Information

Name : Lferr_2568 (Lferr_2568)
Accession : YP_002220969.1
Strain : Acidithiobacillus ferrooxidans ATCC 53993
Genome accession: NC_011206
Putative virulence/resistance : Virulence
Product : two component sigma-54 specific Fis family transcriptional regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG2204
EC number : -
Position : 2539149 - 2540522 bp
Length : 1374 bp
Strand : -
Note : PFAM: response regulator receiver; sigma-54 factor interaction domain-containing protein; SMART: AAA ATPase; KEGG: mfa:Mfla_1055 two component, sigma54 specific, transcriptional regulator, fis family

DNA sequence : 
ATGGAAAAAGGCAGAATCTTACTCGTGGATGATGACGCCGATCTCCTGCGTCTGTTGTCCCTGCGCATGAAGGCGGCCGG
CTATGTGGTCAGCACCGCGGCCAGCGGCAGCGAAGCGTTGTCGGTACTGGCGATGGAGCACCCGTCCCTGGTCATCACCG
ATCTCAAGATGGATGAGATGGACGGTATGGCGCTGCTGGACGCCATTCGCCGCGACTACCCGACGTTGCCCGTCATCATC
CTTACCGCCCACGGTTCCATCCCCGATGCCCTGCTGGCCGCTGACCAGGGTGTCTTTGCCTTCCTCACCAAGCCTTTTGA
TGGCAAGGATCTGATGGCGCAGGTGGAGCGTGCCTTCAACCTGACGGCGGCGGTTCCCCCTTCTTCGGGCAAGAAGGGCC
GGGACTCCAGTTGGGACCGGATCCTGACCCGCAGCCCCAAAATGCAGACGGTGCTGGATCAGGCGCGTCTGGTGGCGGCA
TCCGATGCCAGCGTCTTCATTCATGGCGCCAGTGGTACCGGTAAGGAACTGCTGGCCCAGGCCATCCATCAGGCGAGTCC
GCGCCATGGCCACGCCTTTATTGCCGTCAACTGCGCGGCCTTTCCCGAGCAACTGCTGGAGTCGGAACTCTTCGGGCACA
AAAAGGGCGCCTTCACCGGAGCGGCCAGCAGTCATCAGGGCCTGTTCCAGGCGGCGGAGGGCGGCACGCTTTTTCTGGAC
GAAATTGGCGATATGCCTCTCCCGTTACAGGTCAAACTGCTGCGCGCCCTGCAGGAACGGATGATTCGTCCGGTCGGCGC
CACCGAGAGCATCGCCGTCGACGTGCGGATCATCTCCGCCAGTCACCGGGATTTGGAGCAGGAGATGGCTGCCCGGCGTT
TCCGGGATGATCTCTACTATCGCCTTTGCGTGGTGACCCTGGAACTTCCCGCCCTGGCGGAGCGCCCGGAGGATATCCCG
CTGCTGGCCGAGTTTTTCCTGCGAGATGCGGCGGCCAAGAATCGCAAGGACGTTCGCGGGATCGCGCCGGAAGCCATGGA
ACTGCTCGTATCGGCGCCCTGGCCGGGCAATGTCCGGCAGCTCGCCAACGTCATCGAACAGGCGGTGGTGCTGTCCACTA
CCCCGCGAATCGGGGCGCCCCTCATCCGTCATGCCTTGCGTGACCGGGAAGGGGAGGTCATGCCTCTGGCCGATGCCAAG
GGCCGTTTCGAGATGAATTATCTGATCCAGATCATGCGCATGACCCGCGGCAACGTGAGTCAGGCCGCACAACTCGCACA
GCGCAACCGCACCGAGTTTTATCGCCTCCTGCACCGCTACCACCTCGATCCCGCCGCCTTCAAGGAAGCCGGTGGTGAAG
CGGAGGAGGAGTAG

Protein sequence : 
MEKGRILLVDDDADLLRLLSLRMKAAGYVVSTAASGSEALSVLAMEHPSLVITDLKMDEMDGMALLDAIRRDYPTLPVII
LTAHGSIPDALLAADQGVFAFLTKPFDGKDLMAQVERAFNLTAAVPPSSGKKGRDSSWDRILTRSPKMQTVLDQARLVAA
SDASVFIHGASGTGKELLAQAIHQASPRHGHAFIAVNCAAFPEQLLESELFGHKKGAFTGAASSHQGLFQAAEGGTLFLD
EIGDMPLPLQVKLLRALQERMIRPVGATESIAVDVRIISASHRDLEQEMAARRFRDDLYYRLCVVTLELPALAERPEDIP
LLAEFFLRDAAAKNRKDVRGIAPEAMELLVSAPWPGNVRQLANVIEQAVVLSTTPRIGAPLIRHALRDREGEVMPLADAK
GRFEMNYLIQIMRMTRGNVSQAAQLAQRNRTEFYRLLHRYHLDPAAFKEAGGEAEEE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00300 YP_008207765.1 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Not tested AbaR25 Protein 1e-58 41
BJAB0868_00304 YP_008211630.1 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Not tested AbaR26 Protein 1e-58 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Lferr_2568 YP_002220969.1 two component sigma-54 specific Fis family transcriptional regulator BAC0467 Protein 3e-78 50
Lferr_2568 YP_002220969.1 two component sigma-54 specific Fis family transcriptional regulator BAC0089 Protein 6e-82 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Lferr_2568 YP_002220969.1 two component sigma-54 specific Fis family transcriptional regulator VFG1249 Protein 1e-68 48
Lferr_2568 YP_002220969.1 two component sigma-54 specific Fis family transcriptional regulator VFG1214 Protein 7e-66 45
Lferr_2568 YP_002220969.1 two component sigma-54 specific Fis family transcriptional regulator VFG0116 Protein 9e-56 42