Gene Information

Name : Lferr_2442 (Lferr_2442)
Accession : YP_002220844.1
Strain : Acidithiobacillus ferrooxidans ATCC 53993
Genome accession: NC_011206
Putative virulence/resistance : Unknown
Product : replicative DNA helicase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0305
EC number : -
Position : 2404953 - 2406326 bp
Length : 1374 bp
Strand : -
Note : KEGG: noc:Noc_0223 DnaB helicase; TIGRFAM: replicative DNA helicase; PFAM: DnaB domain protein helicase domain protein; SMART: AAA ATPase

DNA sequence :
GTGTCTGATTCGGCAGACTACGGCGGCGGGGTCAAGGCCCCGCCGCACTCTATTGAGGCGGAGCAATCCGTCATCGGCGC
CCTGCTGATCGACCCCGAGACGGCGGAGCAGGTCACTGAGGCGGTGACGGCCGAAGATTTTTATGAGCGTCGCCACCGCC
AGATTTTCCAGGCTATCAGCGCCATGCTGGGCGCCGGGCGGGCGGTGGACGCCATCACGGTCTCCGAGTGGTTGCAGGAT
CATGAGCAGCTCGCCGATGTGGGCGGGGTGCAGTATCTCCTCATGCTGGCCAACGAGACACCCTCGGCGGCCAATGTGCT
CGCCTATGCGCGGATCGTGCGGGAGCGGGCCACCCTGCGTGACCTCATTCGGGTCGGTCGGGAAATTGCCGAGCTTGCCT
ACCGCCCGGAAGGGCGGCAGGCTCAGGCCTTGTTGGACGAGGCCGAAAGCCGGGTCTTTCATCTCGCCGAAGGACAGCAG
CGAGCCGGTGAAGGCTTCCAGCAACTCAAGGATGCACTTCCGGCGGTTATCGACCGGATCGAGACCATCGCCCGCGAGAG
GAAGGGCGTCACGGGGCTGTCCACGGGCTTTGCCGATCTGGACGAGAAAACCTCCGGCCTCCACCCGGGCCAGCTCGTTA
TTGTCGCGGGCCGTCCGAGTATGGGAAAAACCTCTTTCGCCATGAATATAGCGGAGCATGTCGCCTGTATCGAAGGCAAG
CCTGTCGCGGTCTTCAGCATGGAAATGCCGACCGACGAGATCGTCCTGCGCGCGCTCTCGTCGCGGGGGCGGGTGGATCA
GCACCGCCTGCGCAATGGCAGCCTGGGTAATGACGATTGGCCGCGCATCGCCCACGCCATCGGTGAGCTCGGCAACGCGC
CCCTGTTCGCCGACGATTCTGCCGCGCTGACCCCGACGGATTTGCGCTCGCGGGCGCGTCGGTTGAAGCGGGAGCATGGC
CTGGCTTTGATCGTGGTGGACTATCTGCAACTCATGCAGGTGCCGGGACGGGGTGATAACCGGGTCGCCGAGATTTCCGA
GATCAGCCGCTCGCTCAAGGCGTTGGCCAAAGAGCTGTCGATCCCGGTCATTGCCCTCTCCCAGCTCAACCGAAGTCTGG
AAAATCGTACCGAGAAGCGTCCGCAGATGTCCGATCTGCGCGAATCCGGCGCCATTGAACAGGATGCCGACCTGATCCTC
TTCCTCTATCGCGATGAGGTGTATTACAAGGACAAGGAAGAGGTGAAGGGCATTGCCGAGGTGATCATCGGTAAACAGCG
CAACGGACCCATCGGGACGGTTCGGATGAGTTTCTTCGGTGAATATACCCGTTTTGAGAATTATGCGCCGTCCGGGGATG
GCTTCGGGCATTAG

Protein sequence :
MSDSADYGGGVKAPPHSIEAEQSVIGALLIDPETAEQVTEAVTAEDFYERRHRQIFQAISAMLGAGRAVDAITVSEWLQD
HEQLADVGGVQYLLMLANETPSAANVLAYARIVRERATLRDLIRVGREIAELAYRPEGRQAQALLDEAESRVFHLAEGQQ
RAGEGFQQLKDALPAVIDRIETIARERKGVTGLSTGFADLDEKTSGLHPGQLVIVAGRPSMGKTSFAMNIAEHVACIEGK
PVAVFSMEMPTDEIVLRALSSRGRVDQHRLRNGSLGNDDWPRIAHAIGELGNAPLFADDSAALTPTDLRSRARRLKREHG
LALIVVDYLQLMQVPGRGDNRVAEISEISRSLKALAKELSIPVIALSQLNRSLENRTEKRPQMSDLRESGAIEQDADLIL
FLYRDEVYYKDKEEVKGIAEVIIGKQRNGPIGTVRMSFFGEYTRFENYAPSGDGFGH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed ABR13456.1 replicative DNA helicase Not tested PAGI-5 Protein 1e-92 48
PMI2640 YP_002152342.1 DNA helicase Not tested Not named Protein 3e-84 47
dnaB CAI36044.1 replicative DNA helicase DnaB Not tested PPHGI-1 Protein 1e-76 46
dnaB2 YP_001402701.1 replicative DNA helicase Not tested YAPI Protein 1e-88 46
api2 CAF28476.1 putative DNA binding protein with DNA-dependent ATPase activity Not tested YAPI Protein 5e-88 45
dnaB2 YP_001007676.1 putative DNA helicase Not tested YAPI Protein 3e-84 45
STY4522 NP_458617.1 DNA helicase Not tested SPI-7 Protein 2e-83 45
t4227 NP_807829.1 DNA helicase Not tested SPI-7 Protein 2e-83 45
dnaB1 YP_005176258.1 replicative DNA helicase Not tested ICEPmu1 Protein 1e-72 42